Aristolochic acid exposure in Romania and implications for renal cell carcinoma [PDF]
, 2016 Background: Aristolochic acid (AA) is a nephrotoxicant associated with AA nephropathy (AAN) and upper urothelial tract cancer (UUTC). Whole-genome sequences of 14 Romanian cases of renal cell carcinoma (RCC) recently exhibited mutational signatures ...
AP Grollman +29 more
core +1 more source
Molecular Mechanism of Ochratoxin A Transport in the Kidney
Toxins, 2010 The mycotoxin, ochratoxin A (OTA), is thought to be responsible for Balkan endemic nephropathy. OTA accumulates in several tissues, especially in the kidneys and liver.
Naohiko Anzai +2 more
doaj +1 more source
Aristolochic Acid Induced Suicidal Erythrocyte Death
Kidney & Blood Pressure Research, 2014 Background/Aims: Aristolochic Acid, a component of Aristolochia plants, has been shown to cause acute kidney injury, renal aristolochic acid nephropathy, Balkan endemic nephropathy, and urothelial carcinoma.
Abaid Malik +5 more
doaj +1 more source
Incidence and predictive factors of Balkan Endemic Nephropathy: A longitudinal study
Saudi Journal of Kidney Diseases and Transplantation, 2014 Balkan endemic nephropathy (BEN) is a chronic kidney disease that progresses slowly. There are no known clinical markers to identify an early disease development.
Kesinee Hanjangsit +6 more
doaj +1 more source
Risk factors associated with chronic kidney disease of unknown origin (Ckdu) in North Central Province (NCP) of Sri Lanka: An analysis of evidence to date [PDF]
, 2020 © 2020 The Authors. Published by [Name of Publisher]. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://acquaintpublications.org ...
Aslam, Fahim
core
Mechanisms of Enzyme-Catalyzed Reduction of Two Carcinogenic Nitro-Aromatics, 3-Nitrobenzanthrone and Aristolochic Acid I: Experimental and Theoretical Approaches [PDF]
, 2014 : This review summarizes the results found in studies investigating the enzymatic activation of two genotoxic nitro-aromatics, an environmental pollutant and carcinogen 3-nitrobenzanthrone (3-NBA) and a natural plant nephrotoxin and carcinogen ...
Eva Frei +4 more
core +3 more sources
Increased Glomerular Filtration Rate in Early Stage of Balkan Endemic Nephropathy
Medicina, 2019 Background: A previous study indicated that Balkan endemic nephropathy (BEN) patients in the early stage of the disease had significantly higher creatinine clearance (Ccr) than healthy persons.
Ljubica Djukanović +4 more
doaj +1 more source
Histomorphological and clinical study of primary and secondary glomerulopathies in Southeast Serbia (20-year period of analysis) [PDF]
, 2013 Background/Aim. Epidemiological studies of renal biopsies have been performed to follow up the incidence of glomerular diseases on a specified territory and to compare the obtained results with results from other regions.
Savić Vojin +2 more
core +1 more source
Open questions on Balkan nephropathy [PDF]
Nephrology Dialysis Transplantation, 2001 The prevalence of the disease was stable over manyyears, but now appears to decline in most affectedsettlements w1x. Some authors also suggest that theincidence of BEN decreases w1,2x and that it appearsto be tapering off; others, however, describe a stableincidence of BEN w3x.
L, Djukanović +7 more
openaire +2 more sources
Journal of Kidney Cancer and VHL, 2015 Aristolochic acid (AA) has, in the last decade, become widely promoted as the cause of the Balkan endemic nephropathy and associated renal or urothelial tumours, although without substantial focal evidence of the quantitative dietary exposure via bread ...
Alexandra Gruia +5 more
doaj +1 more source