Results 81 to 90 of about 13,919 (205)
Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase
, 2021 BAP1 is an ubiquitin hydrolase whose deubiquitinase activity is mediated by polycomb group-like protein ASXL2. Cancer-related
mutations/deletions lead to loss-of-function by targeting the catalytic ubiquitin C-terminal hydrolase (UCH) or UCH37-like ...Sementino, Eleonora, Collop, Paul R, Mandell, Jacob P, Harbour, J William, Cassel, Joel, Cheung, Mitchell, Bowcock, Anne M, Kennedy, Eileen J, McCracken, Daniel S, Peng, Hongzhuang, Prokop, Jeremy W, Polo, Alexander, Malkowicz, S Bruce, Testa, Joseph R, Salvino, Joseph, Ayyanathan, Kasirajan, Joshi, Surbhi, Rauscher, 3rd, Frank J, Hinds, David, Joel Cassel, Surbhi Joshi, Kasirajan Ayyanathan, Hongzhuang Peng, S. Bruce Malkowicz, Jeremy W. Prokop, Joseph R. Testa, Jacob P. Mandell, David Hinds, Daniel S. McCracken, Joseph Salvino, Paul R. Collop, Alexander Polo, Mitchell Cheung, J. William Harbour, Eileen J. Kennedy, Anne M. Bowcock, Eleonora Sementino, Frank J. Rauscher +37 morecore +1 more sourceA Case Report of BAP1-inactivated Melanocytoma with Discussion of Possible Dual Roles of BAP1 Loss in Tumorigenesis [PDF]
BRCA1-associated protein (BAP1) is a tumor suppressor involved in a myriad of cellular processes. BAP1-inactivated melanocytomas (BIMs) are rare melanocytic tumors characterized by the loss of nuclear expression of BAP1.Goldenberg, MD*, Alicia V., Guo, MD, PhD, Lili, Andea, MD, MBA, Aleodor (Doru) A., Chen, MD, PhD, MBA, Frank +3 morecore Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide
, 2018 Background:The BRCA1-associated protein-1 (BAP1) tumor predisposition syndrome (BAP1-TPDS) is a hereditary tumor syndrome caused by germline pathogenic variants in BAP1 encoding a tumor suppressor associated with uveal melanoma, mesothelioma, cutaneous ...Repo, P., Cebulla, C.M., Davidorf, F.H., Stoppa-Lyonnet, D., Luyten, G.P.M., Turunen, J.A., van Doorn, R., Jager, M.J., Garfield, E., Stautberg, M., Cheung, M., Njauw, C.N., de la Fouchardière, A., Pritchard, A.L., Walpole, S., Pilarski, R., Cabaret, O., Marinkovic, M., et al., Golmard, L., Pastorino, L., Davidorf, FH, Mastracci, Luca, Nickerson, Michael L, Betti, M., Höiom, Veronica, Helgadottir, H., Santagata, Sandro, Jager, Martine J, Puig, Susana, Jarvinen, RS, Cabaret, Odile, Symmons, Judith, Kiilgaard, J.F., Kim, I., Al-Jamal, R.T., Adlard, Julian, Klein, A. de, Nickerson, ML, de la Fouchardiere, A, Racher, Hilary, Bruno, William, Dianzani, I, Murali, Rajmohan, Symmons, J, Cheung, M, Andreotti, V., Kim, Ivana, Chau, C., Newton-Bishop, J, Bressac-de Paillerets, B, Taibjee, Saleem, Kivelä, Tero T, Bressac-de Paillerets, B., Stern, M.H., Helgadottir, H, Nickerson, M.L., Howlie, Madeleine, Newton-Bishop, J., Kivela, T T, O’Shea, Sally J, Pritchard, Antonia L, Queirolo, Paola, Dalmasso, Bruna, Luyten, GPM, Taibjee, S, Paillerets, Brigitte Bressac-de, Njauw, Ching-Ni, Hamilton, H., Tsao, Hensin, Ossio, R., Wadt, K., Chau, C, Klebe, Sonja, Bergmann, C, Potrony, Miriam, Abdel-Rahman, Mohamed H, Cabaret, O, Turunen, Joni A, Tsao, H, Symmons, J., Kilic, E., Adlard, J., Hamilton, H, Wadt, Karin, Garfield, Erin, Cebulla, CM, Stern, Marc-Henri, Lane, A.M., Mastracci, L., O'Shea, S.J., Ciccarese, G, Dianzani, Irma, Glasson, W., Garfield, E, Mastracci, L, Al-Jamal, Rana’a T, Al-Jamal, R T, Hayward, NK, Dahiya, S., Harbour, J William, Johansson, P, Dalmasso, B., Santagata, S, de, la Fouchardiere A, Warrier, Sunil, Racher, H., Ossio, R, Marinkovic, M, Fouchardiere, A. de la, Marinkovic, Marina, Poplawski, N., Glasson, W, Ciccarese, G., Bergmann, C., Hayward, N.K., Nielsen, M, Pilarski, Robert, van Poppelen, Natasha, Tsao, H., Robles-Espinoza, C.D., Ghiorzo, Paola, Golmard, L, Palmer, Jane M, Poplawski, N, Ghiorzo, P., Golmard, Lisa, Stern, MH, Turunen, JA, Palmer, J.M., Newton-Bishop, Julia, Repo, P, Stoppa-Lyonnet, D, Johansson, P., Adams, David J, Burke, Jo, Davidorf, Frederick H, Stautberg, Meredith, Chau, Cindy, Andreotti, V, Howlie, M, Palmer, JM, Kiilgaard, Jens Folke, Potrony, M., Pritchard, AL, Pilarski, R, Pastorino, Lorenza, Hayward, Nicholas K, Testa, JR, Hoiom, V, Hoiom, V., Murali, R., Gerami, Pedram, Harbour, JW, Helgadottir, Hildur, Ossio, Raul, Warrier, S, Santagata, S., Burke, J, Njauw, CN, Jager, MJ, Testa, Joseph R, Burke, J., Hamilton, Hayley, Potrony, M, Bruno, W, Testa, J.R., Jarvinen, R.S., Adams, DJ, Taibjee, S., Gerami, P., Wadt, K, Stautberg, M, Speicher, Michael R, Al-Jamal, Rana'a T, Speicher, M.R., Lane, Anne-Marie, van Doorn, R, Dianzani, I., Poplawski, Nicola, Walpole, S, Johansson, Peter, Harbour, J.W., Murali, R, Racher, H, Nielsen, Maartje, Betti, Marta, Luyten, Gregorius P M, Betti, M, Robles-Espinoza, CD, Adlard, J, Walpole, Sebastian, Cebulla, Colleen M, Abdel-Rahman, M.H., Queirolo, P, Puig, S., Dalmasso, B, O'Shea, SJ, Ghiorzo, P, Poppelen, N. van, Andreotti, Virginia, Dahiya, S, Kim, I, O'Shea, Sally J, van Doorn, Remco, Bruno, W., Bergmann, Carsten, Glasson, William, Howlie, M., Cheung, Mitchell, Gerami, P, Dahiya, Sonika, Klebe, S, Pastorino, L, Lane, AM, Kiliç, Emine; id_orcid, de la Fouchardière, Arnaud, Kiilgaard, J F, Klebe, S., de Klein, Annelies, Abdel-Rahman, MH, Speicher, MR, Adams, D.J., Queirolo, P., Ciccarese, Giulia, Kivela, T.T., Doorn, R. van, Puig, S, Repo, Pauliina, Warrier, S., Nielsen, M., Stoppa-Lyonnet, Dominique, Kilic, Emine, Robles-Espinoza, Carla Daniela, Järvinen, Reetta-Stiina +234 morecore +2 more sourcesDifferent Prognostic Roles Of Tumor Suppressor Gene BAP1 In Cancer: A Systematic Review With Meta-Analysis
, 2016 Biallelic inactivation of the tumor suppressor gene BRCA1-associated protein 1 (BAP1) has been demonstrated in several cancers, but its prognostic role has not been completely explained. We aimed to investigate the risk associated with loss of BAP1 (BAP1-Alessia Nottegar, Laura D Wood, Stubbs, Brendon, Marco Solmi, Shinichi Yachida, Nicola Veronese, Solmi, M., SCARPA, ALDO, Antonio Pea, Yachida, Shinichi, Capelli, P., Pea, Antonio, VERONESE, NICOLA, Nottegar, A., Pea, A., Claudio Luchini, Matteo Fassan, Cheng, L., Fassan, M., Wood, L. D., Wood, Laura D, SOLMI, MARCO, Liang Cheng, Aldo Scarpa, Veronese, N., Nottegar, Alessia, Barbareschi, Mattia, Yachida, S., Luchini, C., Capelli, Paola, Paola Capelli, Brendon Stubbs, Mattia Barbareschi, Stubbs, Brendon; id_orcid, FASSAN, MATTEO, Luchini, Claudio, Scarpa, A., Stubbs, B., Cheng, Liang, Barbareschi, M. +39 morecore +1 more source
