Results 111 to 120 of about 1,246,132 (248)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Proposed fault diagnostics of a broken rotor bar induction motor fed from PWM inverter

open access: yesJournal of Electrical Systems and Information Technology, 2016
This paper presents a fault diagnostics technique for a three-phase squirrel cage induction motor. The method is developed using a simplified model affected by bar resistance variation.
Faeka M.H. Khater   +3 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Static $\bar{Q}$-$Q$ Potential from $N_f=2$ Dynamical Domain-Wall QCD

open access: yes, 2004
We calculate the static quark and anti-quark potential both in quenched and two-flavor dynamical quark lattice QCD using DBW2 gauge and domain-wall quark actions. Lattice spacings from Sommer scale are determined.
Hashimoto, Koichi, Izubuchi, Taku
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

The Researches on Damage Detection Method for Truss Structures

open access: yesE3S Web of Conferences, 2018
This paper presents an effective method to detect damage in truss structures. Numerical simulation and experimental analysis were carried out on a damaged truss structure under instantaneous excitation.
Wang Meng Hong, Cao Xiao Nan
doaj   +1 more source

Crack Detection of FRP-Reinforced Concrete Beam Using Embedded Piezoceramic Smart Aggregates

open access: yesSensors, 2019
In this paper, the authors present a stress wave-based active sensing method to detect the crack in FRP-reinforced concrete beams. The embedded smart aggregates (SAs), which utilize Lead Zirconate Titanate (PZT) as transducers, are employed in this ...
Tianyong Jiang   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy