The F-BAR Domain of Rga7 Relies on a Cooperative Mechanism of Membrane Binding with a Partner Protein during Fission Yeast Cytokinesis [PDF]
Cell Reports, 2019 Summary: F-BAR proteins bind the plasma membrane (PM) to scaffold and organize the actin cytoskeleton. To understand how F-BAR proteins achieve their PM association, we studied the localization of a Schizosaccharomyces pombe F-BAR protein Rga7, which ...
Yajun Liu +4 more
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The Predicted Structure of S. cerevisiae Ssp1 Reveals Parallel Evolution in the Pil1 BAR Domain Family Proteins of Ascomycetes [PDF]
Journal of FungiBAR domains are a superfamily of widely conserved membrane binding motifs. In fungi, Pil1 family proteins are BAR domain containing proteins involved in organizing the plasma membrane. S.
Yasuyuki Suda, Aaron M. Neiman
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The BAR Domain Superfamily Proteins from Subcellular Structures to Human Diseases
Membranes, 2012 Eukaryotic cells have complicated membrane systems. The outermost plasma membrane contains various substructures, such as invaginations and protrusions, which are involved in endocytosis and cell migration.
Fatemeh Safari, Shiro Suetsugu
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The Role of BAR Domain Proteins in the Regulation of Membrane Dynamics. [PDF]
Acta Naturae, 2016 Many cellular processes are associated with membrane remodeling. The BAR domain protein family plays a key role in the formation and detection of local membrane curvatures and in attracting other proteins, including the regulators of actin dynamics. Based on their structural and phylogenetic properties, BAR domains are divided into several groups which
Stanishneva-Konovalova TB +3 more
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Salt Bridge Formation between the I-BAR Domain and Lipids Increases Lipid Density and Membrane Curvature [PDF]
Scientific Reports, 2017 The BAR domain superfamily proteins sense or induce curvature in membranes. The inverse-BAR domain (I-BAR) is a BAR domain that forms a straight “zeppelin-shaped” dimer.
Kazuhiro Takemura +3 more
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LdFlabarin, a new BAR domain membrane protein of Leishmania flagellum. [PDF]
PLoS ONE, 2013 During the Leishmania life cycle, the flagellum undergoes successive assembly and disassembly of hundreds of proteins. Understanding these processes necessitates the study of individual components.
Michèle Lefebvre +10 more
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Protein Folding Mechanism of the Dimeric AmphiphysinII/Bin1 N-BAR Domain. [PDF]
PLoS ONE, 2015 The human AmphyphisinII/Bin1 N-BAR domain belongs to the BAR domain superfamily, whose members sense and generate membrane curvatures. The N-BAR domain is a 57 kDa homodimeric protein comprising a six helix bundle.
Tobias Gruber, Jochen Balbach
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The BAR domain of the Arf GTPase-activating protein ASAP1 directly binds actin filaments [PDF]
Journal of Biological Chemistry, 2020 Pei-Wen Chen +2 more
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BAR domain proteins—a linkage between cellular membranes, signaling pathways, and the actin cytoskeleton [PDF]
Biophysical Reviews, 2018 Peter J Carman +2 more
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Frontiers in Molecular Biosciences, 2021 PICK1 is a multi-domain scaffolding protein that is uniquely comprised of both a PDZ domain and a BAR domain. While previous experiments have shown that the PDZ domain and the linker positively regulate the BAR domain and the C-terminus negatively ...
Amy O. Stevens, Yi He
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