APPL proteins FRET at the BAR: direct observation of APPL1 and APPL2 BAR domain-mediated interactions on cell membranes using FRET microscopy. [PDF]
PLoS ONE, 2010 Human APPL1 and APPL2 are homologous RAB5 effectors whose binding partners include a diverse set of transmembrane receptors, signaling proteins, and phosphoinositides.
Heidi J Chial, Peter Lenart, Yong Q Chen
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BAR domain competition during directional cellular migration [PDF]
Cell Cycle, 2010 While directed cellular migration facilitates the coordinated movement of cells during development and tissue repair, the precise mechanisms regulating the interplay between the extracellular environment, the actin cytoskeleton, and the overlying plasma membrane remain inadequately understood.
Gabriel A, Quiñones, Anthony E, Oro
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Calmodulin Promotes N-BAR Domain-Mediated Membrane Constriction and Endocytosis. [PDF]
Dev Cell, 2016 Membrane remodeling by BAR (Bin, Amphiphysin, RVS) domain-containing proteins, such as endophilins and amphiphysins, is integral to the process of endocytosis. However, little is known about the regulation of endocytic BAR domain activity.
Myers MD +3 more
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Phagocytosis is mediated by two-dimensional assemblies of the F-BAR protein GAS7
Nature Communications, 2019 The Bin/Amphiphysin/Rvs167 (BAR) domain superfamily, which includes FCH-BAR (F-BAR) domain proteins are membrane-sculpting proteins. Here the authors combine a range of techniques and show that the F-BAR domain of growth-arrest specific protein 7 (GAS7 ...
Kyoko Hanawa-Suetsugu +19 more
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A mutational analysis of the endophilin-A N-BAR domain performed in living flies. [PDF]
PLoS ONE, 2010 BACKGROUND: Endophilin is a cytoplasmic protein with an important function in clathrin-dependent endocytosis at synapses and elsewhere. Endophilin has a BAR (Bin/Amphiphysin/Rvs-homology) domain, which is implicated in the sensing and induction of ...
Anita G Jung +5 more
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Dielectric analysis of degraded stator bars of a hydro generator
Energy Reports, 2022 This paper presents the investigation of dielectric analysis of degraded stator bars by Polarization and Depolarization Current (PDC) measurement. The stator bars obtained from the 30-year in-service synchronous machine were divided into two groups.
Norasage Pattanadech +4 more
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Structural Basis of Membrane Invagination by F-BAR Domains [PDF]
Cell, 2008 BAR superfamily domains shape membranes through poorly understood mechanisms. We solved structures of F-BAR modules bound to flat and curved bilayers using electron (cryo)microscopy. We show that membrane tubules form when F-BARs polymerize into helical coats that are held together by lateral and tip-to-tip interactions. On gel-state membranes or after
Frost, Adam +7 more
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An Amphiphysin-Like Domain in Fus2p Is Required for Rvs161p Interaction and Cortical Localization
G3: Genes, Genomes, Genetics, 2016 Cell–cell fusion fulfils essential roles in fertilization, development and tissue repair. In the budding yeast, Saccharomyces cerevisiae, fusion between two haploid cells of opposite mating type generates the diploid zygote.
Richard A. Stein +2 more
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Cooperation of Phosphoinositides and BAR Domain Proteins in Endosomal Tubulation [PDF]
Traffic, 2006 Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate many intracellular events, including vesicular trafficking and actin remodeling, by recruiting proteins to their sites of function. PtdIns(4,5)‐bisphosphate [PI(4,5)P2] and related phosphoinositides are mainly synthesized by type I PtdIns‐4‐phosphate 5‐kinases (PIP5Ks).
Naeko, Shinozaki-Narikawa +2 more
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Tailoring magnetization reversal of a single-domain bar nanomagnet via its end geometry
AIP Advances, 2021 Nanoscale single-domain bar magnets are building blocks for a variety of fundamental and applied mesoscopic magnetic systems, such as artificial spin ices, magnetic shape-morphing microbots, and magnetic majority logic gates.
Jianhua Li +14 more
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