Results 61 to 70 of about 34,094 (267)
ChemistryOpen, EarlyView.This study evaluates the pharmacological properties of the aqueous extract of Atractylis aristata, focusing on its antioxidant, anti‐inflammatory, antibacterial, and sedative activities. Phytochemical analysis identifies bioactive compounds, while in vitro and in vivo tests demonstrate its therapeutic potential in addressing oxidative stress ...
Asma Abid +14 more
wiley +1 more source
Embedding Pharmacogenetics Into Clinical Practice to Improve Patient Outcomes
Annals of Human Genetics, EarlyView.ABSTRACT Pharmacogenomics, the use of germline genomic data to guide prescription to improve effective and safer medication, holds promise as a clinical intervention. To date in most health systems, there has been limited uptake of pharmacogenomic testing confined to a few single drug–gene associations.
John Henry McDermott +3 more
wiley +1 more source
An Interesting Case of Barbiturate Automatism and Review of Literature
Case Reports in Neurological Medicine, 2013 A 48 year old man with a diagnosis of HIV infection since 1993, on highly active anti-retro viral therapy (HAART) with stable CD4 count and undetectable viral load for years and seizure disorder presented with recurrent drowsiness. His seizures were well
Sankalp Gokhale, Ciro Ramos-Estebanez
doaj +1 more source
Clinical problems with the performance of euthanasia and physician-assisted suicide in The Netherlands [PDF]
, 2000 BACKGROUND AND METHODS: The characteristics and frequency of clinical problems with the performance of euthanasia and physician-assisted suicide are uncertain. We analyzed data from two studies of euthanasia and physician-
Groenewoud, J.H. (Hanny) +5 more
core +2 more sources
Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
British Journal of Pharmacology, EarlyView.Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander +5 more
wiley +1 more source
Acta Crystallographica Section E, 2013 The title compound, C15H18N4O7, is a product of the substitution reaction of 5,5-dibromo-1,3-dimethylbarbituric acid with sodium sulfide in aqueous acetone.
Manfred Steimann, Kamal Sweidan
doaj +1 more source
Epilepsia, Volume 66, Issue 3, Page 674-685, March 2025.Abstract Objective Large language models (LLMs) have recently gained attention for clinical decision‐making and diagnosis. This study evaluates the performance of the recently updated LLM Chat Generative Pre‐Trained Transformer‐4omni (ChatGPT‐4o) in predicting clinical outcomes in patients with status epilepticus and compares its prognostic performance
Simon A. Amacher +10 more
wiley +1 more source
Clonidine-Activation of Epileptic Foci
Pediatric Neurology Briefs, 1998 The effects of clonidine, an adrenergic a2 agonist hypotensive agent, and methoxital, a short-acting barbiturate anesthetic, on epileptiform discharges detected by presurgical magnetoencephalography (MEG) were investigated in 14 patients with medically ...
J Gordon Millichap
doaj +1 more source
Specialized neurocritical care, severity grade, and outcome of patients with aneurysman subarachnoid hemorrhage [PDF]
, 2018 Introduction: To evaluate the impact of specialized neurocritical care on the population admitted to a neurovascular center and on the outcome of patients with severe aneurysmal subarachnoid hemorrhage (aSAH). Methods: After exclusion of patients treated
Bjeljac, Miroslava +4 more
core
Practical and comprehensive guidelines for bedside cerebral hemometabolic multitherapeutic optimization [PDF]
, 2002 In recent years, noncomprehensive guidelines were proposed for the management of severe acute brain injuries, focusing strictly on two approaches: 1) to maintain cerebral perfusion pressure anywhere above 70 mm Hg; and 2) to maintain arterial carbon ...
Cruz, Julio
core +3 more sources