Results 61 to 70 of about 34,333 (275)

Optimizing phenobarbital dosing in critically ill patients with refractory and superrefractory status epilepticus using a population pharmacokinetic model

open access: yesEpilepsia, EarlyView.
Abstract Objective Current weight‐based dosing fails to account for pharmacokinetic variability in refractory and superrefractory status epilepticus (RSE, SRSE). However, understanding pharmacokinetics in critically ill patients with varying degrees of organ dysfunction can improve both safety and efficacy.
Maximilian Stoschus   +9 more
wiley   +1 more source

Persistent vegetative state secondary to a motor vehicle accident [PDF]

open access: yes, 2012
The case presents a young girl who was involved in a road traffic accident. Despite being alive at present, her body cannot perform any basic functions since she is in a persistent vegetative state.
Abela, Franklin, Dimech, Anthony
core  

Sleep quality and its correlates in people with epilepsy: A multicenter cross‐sectional study in Germany

open access: yesEpilepsia, EarlyView.
Abstract Objective Sleep disturbances and epilepsy are closely interrelated. This study aimed to examine associations between sleep quality, affective symptoms, and quality of life (QoL) in people with epilepsy (PWE), and to identify clinical and sociodemographic factors linked to impaired sleep. Methods We conducted a multicenter cross‐sectional study
Johann Philipp Zöllner   +11 more
wiley   +1 more source

Prolonged aura or status epilepticus? Unmasking a first‐time migraine attack

open access: yes
Epileptic Disorders, EarlyView.
Tiago Lerda Casaccia   +6 more
wiley   +1 more source

Peripheral blood mononuclear cell secretome from patients with autoimmune encephalitis promotes seizures in vitro

open access: yesEpilepsia, EarlyView.
Abstract Objective Autoimmune encephalitis (AE) is characterized by inflammatory processes in the central nervous system and frequently presents with seizures. Even though an ictogenic potential has been shown for some antibodies against neuronal surface antigens (NSAbs), AE pathophysiology is complex, and NSAbs‐independent mechanisms are likely to ...
Sara Prevosti   +14 more
wiley   +1 more source

Clonidine-Activation of Epileptic Foci

open access: yesPediatric Neurology Briefs, 1998
The effects of clonidine, an adrenergic a2 agonist hypotensive agent, and methoxital, a short-acting barbiturate anesthetic, on epileptiform discharges detected by presurgical magnetoencephalography (MEG) were investigated in 14 patients with medically ...
J Gordon Millichap
doaj   +1 more source

An extreme type of new onset refractory status epilepticus with stimulus‐induced seizures in pharmacological isoelectric states

open access: yesEpilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is a common neurological emergency associated with high morbidity and mortality. SE is classified as refractory when it persists despite benzodiazepine and second‐line antiseizure medication. Managing refractory SE in the intensive care setting often requires high doses of sedative drugs, which can induce ...
Julie Lévi‐Strauss   +6 more
wiley   +1 more source

Drugs analysis using latex agglutination tests

open access: yesТонкие химические технологии, 2011
The method of latex agglutination was used to develop express diagnostics of the most extended groups of drugs (opiates, cannabinoides and barbiturates).
N. М. Solodukhina   +3 more
doaj  

An Interesting Case of Barbiturate Automatism and Review of Literature

open access: yesCase Reports in Neurological Medicine, 2013
A 48 year old man with a diagnosis of HIV infection since 1993, on highly active anti-retro viral therapy (HAART) with stable CD4 count and undetectable viral load for years and seizure disorder presented with recurrent drowsiness. His seizures were well
Sankalp Gokhale, Ciro Ramos-Estebanez
doaj   +1 more source

State-Dependent Modulation of Slow Wave Motifs towards Awakening

open access: yesFrontiers in Cellular Neuroscience, 2017
Slow cortical waves that propagate across the cerebral cortex forming large-scale spatiotemporal propagation patterns are a hallmark of non-REM sleep and anesthesia, but also occur during resting wakefulness.
Thomas Knöpfel   +6 more
doaj   +1 more source

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