Results 61 to 70 of about 34,815 (271)

Optimizing phenobarbital dosing in critically ill patients with refractory and superrefractory status epilepticus using a population pharmacokinetic model

Epilepsia, EarlyView.
Abstract Objective Current weight‐based dosing fails to account for pharmacokinetic variability in refractory and superrefractory status epilepticus (RSE, SRSE). However, understanding pharmacokinetics in critically ill patients with varying degrees of organ dysfunction can improve both safety and efficacy.
Maximilian Stoschus, Moritz L. Schmidbauer, Johannes Starp, Stefan Kunst, Georgios Gakis, Michael Paal, Michael Vogeser, Christina Scharf‐Janssen, Uwe Liebchen, Konstantinos Dimitriadis   +9 more
wiley   +1 more source

Drugs analysis using latex agglutination tests

Тонкие химические технологии, 2011
The method of latex agglutination was used to develop express diagnostics of the most extended groups of drugs (opiates, cannabinoides and barbiturates).
N. М. Solodukhina, Т. V. Abramenko, М. А. Myagkova, I. А. Gritskova   +3 more
doaj  

Step-down infusion of barbiturate improves neurofunction in a new rat model of rebleeding subarachnoid hemorrhage

Brain Hemorrhages
Objective: Rebleeding from a ruptured aneurysm is a risk factor for fatal prognosis in subarachnoid hemorrhage (SAH). A novel barbiturate treatment, step-down infusion of barbiturate (sd-B), was previously developed; it showed beneficial effects on ...
Sosho Kajiwara, Yu Hasegawa, Kana Fujimori, Motohiro Morioka   +3 more
doaj   +1 more source

Sleep quality and its correlates in people with epilepsy: A multicenter cross‐sectional study in Germany

Epilepsia, EarlyView.
Abstract Objective Sleep disturbances and epilepsy are closely interrelated. This study aimed to examine associations between sleep quality, affective symptoms, and quality of life (QoL) in people with epilepsy (PWE), and to identify clinical and sociodemographic factors linked to impaired sleep. Methods We conducted a multicenter cross‐sectional study
Johann Philipp Zöllner, Catrin Mann, Laurent Willems, Felix von Podewils, Lisa Langenbruch, Laura Bierhansl, Susanne Knake, Katja Menzler, Juliane Schulz, Bernadette Gaida, Felix Rosenow, Adam Strzelczyk   +11 more
wiley   +1 more source

5-[1-(1,3-Dimethyl-2,4,6-trioxohexahydropyrimidin-5-yl)-2-oxopropyl]-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione

Acta Crystallographica Section E, 2013
The title compound, C15H18N4O7, is a product of the substitution reaction of 5,5-dibromo-1,3-dimethylbarbituric acid with sodium sulfide in aqueous acetone.
Manfred Steimann, Kamal Sweidan
doaj   +1 more source

Persistent vegetative state secondary to a motor vehicle accident [PDF]

, 2012
The case presents a young girl who was involved in a road traffic accident. Despite being alive at present, her body cannot perform any basic functions since she is in a persistent vegetative state.
Abela, Franklin, Dimech, Anthony
core  

Effect of different agonistic experiences on behavioural seizures in fully amygdala kindled rats [PDF]

, 1992
Fully amygdala kindled rats were exposed to two different inter-male agonistic experiences in order to study the interaction between epilepsy and acute social stress.
Beldhuis, Hans J.A.,, Bohus, Béla,, Koolhaas, Jaap M.,   +2 more
core   +2 more sources

Peripheral blood mononuclear cell secretome from patients with autoimmune encephalitis promotes seizures in vitro

Epilepsia, EarlyView.
Abstract Objective Autoimmune encephalitis (AE) is characterized by inflammatory processes in the central nervous system and frequently presents with seizures. Even though an ictogenic potential has been shown for some antibodies against neuronal surface antigens (NSAbs), AE pathophysiology is complex, and NSAbs‐independent mechanisms are likely to ...
Sara Prevosti, Alessio Passalacqua, Maria Cristina Regondi, Giada D'Ambrosio, Alessandra Morano, Michele Romoli, Giulia Maira, Flavio Villani, Pietro Mattioli, Diego Franciotta, Andrea Stabile, Marco de Curtis, Matteo Gastaldi, Francesco Deleo, Laura Librizzi   +14 more
wiley   +1 more source

An extreme type of new onset refractory status epilepticus with stimulus‐induced seizures in pharmacological isoelectric states

Epilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is a common neurological emergency associated with high morbidity and mortality. SE is classified as refractory when it persists despite benzodiazepine and second‐line antiseizure medication. Managing refractory SE in the intensive care setting often requires high doses of sedative drugs, which can induce ...
Julie Lévi‐Strauss, Vi‐Huong Nguyen‐Michel, Espártaco Moraes Ribeiro, Virginie Lambrecq, Aurélie Hanin, Sophie Demeret, Vincent Navarro   +6 more
wiley   +1 more source

New‐Onset Psychosis in a Person with Parkinson's Disease after “Horny Goat Weed” Use

Movement Disorders Clinical Practice, EarlyView.
Juan R. Deliz, Kasra Manoocheri, Danielle N. Larson, Danny Bega   +3 more
wiley   +1 more source