Results 1 to 10 of about 66,176 (317)
BMC Neurology, 2019 Background Several studies have compared the efficacy and safety of propofol and barbiturates in the treatment of refractory status epilepticus (RSE). This study aims to quantitatively assess the advantages and disadvantages of propofol and barbiturates ...
Qing Zhang, Yun Yu, Yu Lu, Hongli Yue
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Recognition of anesthetic barbiturates by a protein binding site: a high resolution structural analysis. [PDF]
PLoS ONE, 2012 Barbiturates potentiate GABA actions at the GABA(A) receptor and act as central nervous system depressants that can induce effects ranging from sedation to general anesthesia.
Simon Oakley +7 more
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Journal of Medicinal Chemistry, 2021 We report a series of synthetic cationic amphipathic barbiturates inspired by the pharmacophore model of small antimicrobial peptides (AMPs) and the marine antimicrobials eusynstyelamides.
M. Paulsen +12 more
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Neuropsychopharmacology Reports, 2022 Background Depression is a common disorder that affects patients' quality of life and incurs health system costs. Due to the resistance to treat depression, better understanding of neurophysiology was considered; one of the implications is the ...
Ahmad Shamabadi
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PLoS ONE, 2022 Barbiturates are proposed as a second/third line treatment for intracranial hypertension in traumatic brain injury (TBI) patients, but the literature remains uncertain regarding their benefit/risk balance.
Maxime Léger +11 more
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Comparative analysis of suicidal poisoning autopsied at the Institute of forensic medicine in Belgrade [PDF]
Praxis Medica, 2014 Number of poisons which surround the modern man is constantly on the rise and hence therefore the frequency of intoxication. The aim of the study was to determine the type of poison which causes the suicidal poisoning, sex, age, occupation, place of ...
Jakšić Vladimir +3 more
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Narcotics Addiction and Its Treatment [PDF]
, 1957 The ongoing mythologizing of the poet in both criticism and, as recently in a play produced by Wasa teater (Vasa), is reductive, and needs to be confronted.
Winick, Charles
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Doctor or drug dealer? International legal provisions for the legitimate handling of drugs of abuse [PDF]
, 2020 © The Author(s) 2020. The final, definitive version of this paper has been published in: Gallagher, C. T., Atik, S. K., Isse, L., & Mann, S. K. (2020). Doctor or drug dealer?
Atik, Sanaa +3 more
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New Methodology for the Synthesis of Thiobarbiturates Mediated by Manganese(III) Acetate
Molecules, 2012 A three step synthesis of various thiobarbiturate derivatives 17–24 was established. The first step is mediated by Mn(OAc)3, in order to generate a carbon-carbon bond between a terminal alkene and malonate.
Patrice Vanelle +2 more
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Frontiers in Pharmacology, 2023 Zulresso (brexanolone) is an aqueous formulation of the neurosteroid, allopregnanolone, and the only FDA-approved medication for the treatment of postpartum depression (PPD).
Alexander B. Horwitz +2 more
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