Results 1 to 10 of about 48,209 (275)

Early use of barbiturates is associated with increased mortality in traumatic brain injury patients from a propensity score-based analysis of a prospective cohort.

PLoS ONE, 2022
Barbiturates are proposed as a second/third line treatment for intracranial hypertension in traumatic brain injury (TBI) patients, but the literature remains uncertain regarding their benefit/risk balance.
Maxime Léger, Denis Frasca, Antoine Roquilly, Philippe Seguin, Raphaël Cinotti, Claire Dahyot-Fizelier, Karim Asehnoune, Florent Le Borgne, Thomas Gaillard, Yohann Foucher, Sigismond Lasocki, for AtlanRéa group   +11 more
doaj   +2 more sources

Integration of thin layer chromatography and smartphone-based colorimetric analysis for the detection of barbiturates

Green Analytical Chemistry
Barbiturates, a key class of psychoactive drugs, present challenges in accurate detection due to their misuse and involvement in forensic investigations.
Keneuoe Letumanyane, Elisa Kalugendo
doaj   +2 more sources

Barbiturates and fractures. [PDF]

BMJ, 1977
Thelma B. Dunn
openalex   +4 more sources

Topiramate and other kainate receptor antagonists for depression: A systematic review of randomized controlled trials

Neuropsychopharmacology Reports, 2022
Background Depression is a common disorder that affects patients' quality of life and incurs health system costs. Due to the resistance to treat depression, better understanding of neurophysiology was considered; one of the implications is the ...
Ahmad Shamabadi
doaj   +1 more source

Comparative analysis of suicidal poisoning autopsied at the Institute of forensic medicine in Belgrade [PDF]

Praxis Medica, 2014
Number of poisons which surround the modern man is constantly on the rise and hence therefore the frequency of intoxication. The aim of the study was to determine the type of poison which causes the suicidal poisoning, sex, age, occupation, place of ...
Jakšić Vladimir, Matejić S., Atanasijević T., Milošević M.   +3 more
doaj   +1 more source

Narcotics Addiction and Its Treatment [PDF]

, 1957
The ongoing mythologizing of the poet in both criticism and, as recently in a play produced by Wasa teater (Vasa), is reductive, and needs to be confronted.
Winick, Charles
core   +4 more sources

Barbiturates and pyrazolopyridines for the treatment of postpartum depression—repurposing of two drug classes

Frontiers in Pharmacology, 2023
Zulresso (brexanolone) is an aqueous formulation of the neurosteroid, allopregnanolone, and the only FDA-approved medication for the treatment of postpartum depression (PPD).
Alexander B. Horwitz, Robert T. Rubin, Robert T. Rubin   +2 more
doaj   +1 more source

Doctor or drug dealer? International legal provisions for the legitimate handling of drugs of abuse [PDF]

, 2020
© The Author(s) 2020. The final, definitive version of this paper has been published in: Gallagher, C. T., Atik, S. K., Isse, L., & Mann, S. K. (2020). Doctor or drug dealer?
Atik, Sanaa, Gallagher, Cathal, Isse, Libin, Mann, Sanpreet   +3 more
core   +2 more sources

Sedation-Induced Burst Suppression Predicts Positive Outcome Following Traumatic Brain Injury

Frontiers in Neurology, 2021
While electroencephalogram (EEG) burst-suppression is often induced therapeutically using sedatives in the intensive care unit (ICU), there is hitherto no evidence with respect to its association to outcome in moderate-to-severe neurological patients. We
Joel Frohlich, Micah A. Johnson, David L. McArthur, Evan S. Lutkenhoff, John Dell'Italia, Courtney Real, Vikesh Shrestha, Norman M. Spivak, Jesús E. Ruiz Tejeda, Paul M. Vespa, Martin M. Monti, Martin M. Monti   +11 more
doaj   +1 more source

New Methodology for the Synthesis of Thiobarbiturates Mediated by Manganese(III) Acetate

Molecules, 2012
A three step synthesis of various thiobarbiturate derivatives 17–24 was established. The first step is mediated by Mn(OAc)3, in order to generate a carbon-carbon bond between a terminal alkene and malonate.
Patrice Vanelle, Christophe Curti, Ahlem Bouhlel   +2 more
doaj   +1 more source