Results 11 to 20 of about 19,466 (148)

Association Between Spinal Manipulation, Butalbital Prescription, and Medication Overuse Headache in Adults With Tension‐Type Headache: Retrospective Cohort Study [PDF]

Health Science Reports
Background and Aims Butalbital is an acute headache medication commonly prescribed for tension‐type headache (TTH), although discouraged by guidelines due to a risk of medication overuse headache (MOH).
Robert J. Trager, Timothy J. Williamson, Pratheek S. Makineni, Lindsay H. Morris   +3 more
doaj   +2 more sources

Water Intoxication Caused by an Overdose of Powdered Herbal Medicine: A Case Report [PDF]

Clin Case Rep
ABSTRACT Large doses of powdered herbal medicines can cause water intoxication due to excessive water intake. Clinicians should consider this risk alongside the medicine's side effects for timely diagnosis and management.
Maki Y, Tsuchiya A, Morita S, Nakagawa Y.   +3 more
europepmc   +2 more sources

Topiramate and other kainate receptor antagonists for depression: A systematic review of randomized controlled trials

Neuropsychopharmacology Reports, 2022
Background Depression is a common disorder that affects patients' quality of life and incurs health system costs. Due to the resistance to treat depression, better understanding of neurophysiology was considered; one of the implications is the ...
Ahmad Shamabadi
doaj   +1 more source

Early use of barbiturates is associated with increased mortality in traumatic brain injury patients from a propensity score-based analysis of a prospective cohort.

PLoS ONE, 2022
Barbiturates are proposed as a second/third line treatment for intracranial hypertension in traumatic brain injury (TBI) patients, but the literature remains uncertain regarding their benefit/risk balance.
Maxime Léger, Denis Frasca, Antoine Roquilly, Philippe Seguin, Raphaël Cinotti, Claire Dahyot-Fizelier, Karim Asehnoune, Florent Le Borgne, Thomas Gaillard, Yohann Foucher, Sigismond Lasocki, for AtlanRéa group   +11 more
doaj   +1 more source

Comparative analysis of suicidal poisoning autopsied at the Institute of forensic medicine in Belgrade [PDF]

Praxis Medica, 2014
Number of poisons which surround the modern man is constantly on the rise and hence therefore the frequency of intoxication. The aim of the study was to determine the type of poison which causes the suicidal poisoning, sex, age, occupation, place of ...
Jakšić Vladimir, Matejić S., Atanasijević T., Milošević M.   +3 more
doaj   +1 more source

Preclinical common data elements for general pharmacological studies (pharmacokinetic sample collection, tolerability, and drug administration). A report of the TASK3‐WG1A General Pharmacology Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2023
Abstract Growing concerns over rigor and reproducibility of preclinical studies, including consistency across laboratories and translation to clinical populations, have triggered efforts to harmonize methodologies. This includes the first set of preclinical common data elements (CDEs) for epilepsy research studies, as well as Case Report Forms (CRFs ...
Lisa Coles, Patrick A. Forcelli, Karine Leclercq, Anna‐Maria Katsarou, Brian D. Klein, Heidrun Potschka, Rudiger Koehling, Lauren Harte‐Hargrove, Aristea S. Galanopoulou, Cameron S. Metcalf   +9 more
wiley   +1 more source

Sedation-Induced Burst Suppression Predicts Positive Outcome Following Traumatic Brain Injury

Frontiers in Neurology, 2021
While electroencephalogram (EEG) burst-suppression is often induced therapeutically using sedatives in the intensive care unit (ICU), there is hitherto no evidence with respect to its association to outcome in moderate-to-severe neurological patients. We
Joel Frohlich, Micah A. Johnson, David L. McArthur, Evan S. Lutkenhoff, John Dell'Italia, Courtney Real, Vikesh Shrestha, Norman M. Spivak, Jesús E. Ruiz Tejeda, Paul M. Vespa, Martin M. Monti, Martin M. Monti   +11 more
doaj   +1 more source

Barbiturates and pyrazolopyridines for the treatment of postpartum depression—repurposing of two drug classes

Frontiers in Pharmacology, 2023
Zulresso (brexanolone) is an aqueous formulation of the neurosteroid, allopregnanolone, and the only FDA-approved medication for the treatment of postpartum depression (PPD).
Alexander B. Horwitz, Robert T. Rubin, Robert T. Rubin   +2 more
doaj   +1 more source

New Methodology for the Synthesis of Thiobarbiturates Mediated by Manganese(III) Acetate

Molecules, 2012
A three step synthesis of various thiobarbiturate derivatives 17–24 was established. The first step is mediated by Mn(OAc)3, in order to generate a carbon-carbon bond between a terminal alkene and malonate.
Patrice Vanelle, Christophe Curti, Ahlem Bouhlel   +2 more
doaj   +1 more source

Buthalital and methitural – 5,5-substituted derivatives of 2-thiobarbituric acid forming the same type of hydrogen-bonded chain

Acta Crystallographica Section E: Crystallographic Communications, 2017
The molecule of buthalital, (I) [systematic name: 5-(2-methylpropyl)-5-(prop-2-en-1-yl)-2-sulfanylidene-1,3-diazinane-4,6-dione], C11H16N2O2S, exhibits a planar pyrimidine ring, whereas the pyrimidine ring of methitural, (II) [systematic name: 5-(1 ...
Thomas Gelbrich, Ulrich J. Griesser
doaj   +1 more source