Results 11 to 20 of about 20,407 (174)

Medicines for Anxiety: A Hundred Years of Tranquillity and More to Come? [PDF]

open access: yesHum Psychopharmacol
Human Psychopharmacology: Clinical and Experimental, Volume 41, Issue 2, March 2026.
Nutt D.
europepmc   +2 more sources

Evaluation of Potentially Inappropriate Medications Prescribed to Older Adults Upon Emergency Department Discharge. [PDF]

open access: yesAcad Emerg Med
ABSTRACT Background Older adults are susceptible to adverse drug effects due to age‐related changes, a higher prevalence of comorbidities, and complexities in medication management. Nearly half of geriatric patients are prescribed at least one new medication at ED discharge.
Schowe J   +4 more
europepmc   +2 more sources

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

A Letter About Phenobarbital Poisoning [PDF]

open access: yesInternational Journal of Medical Toxicology and Forensic Medicine, 2020
The ever-increasing sensitivity of humans and living in a world full of stress and anxiety have led to the increased consumption of painkillers and sleeping pills. Barbiturates, which are among the most important sedatives, are regularly used by ordinary
Zahra Ataee , Maryam Sayyari Doughabadi
doaj   +1 more source

Barbiturate-refractory epilepsy: safe schedule for therapeutic substitution

open access: yesArquivos de Neuro-Psiquiatria, 1986
Barbiturates are considered first line antiepileptic drugs in third world countries due to traditional and economic reasons. This prospective uncontrolled study of 52 patients aged 15 to 64 years (mean 24) demonstrates that patients who become refractory
Ana Maria Gorz   +2 more
doaj   +1 more source

The use of barbiturate-induced coma during cerebrovascular neurosurgery procedures: A review of the literature

open access: yesBrain Circulation, 2015
Barbiturates are indicated for use during vascular neurosurgery procedures such as carotid surgery, arteriovenous malformation (AVM) surgery, cerebral aneurysm surgery, extracranial-intracranial bypass, and following significant bleeding due to AVMs or ...
Nathaniel R Ellens   +2 more
doaj   +1 more source

Recognition of anesthetic barbiturates by a protein binding site: a high resolution structural analysis. [PDF]

open access: yesPLoS ONE, 2012
Barbiturates potentiate GABA actions at the GABA(A) receptor and act as central nervous system depressants that can induce effects ranging from sedation to general anesthesia.
Simon Oakley   +7 more
doaj   +1 more source

Antibacterial Barbituric Acid Analogues Inspired from Natural 3-Acyltetramic Acids; Synthesis, Tautomerism and Structure and Physicochemical Property-Antibacterial Activity Relationships

open access: yesMolecules, 2015
The synthesis, tautomerism and antibacterial activity of novel barbiturates is reported. In particular, 3-acyl and 3-carboxamidobarbiturates exhibited antibacterial activity, against susceptible and some resistant Gram-positive strains of particular ...
Yong-Chul Jeong, Mark G. Moloney
doaj   +1 more source

Implementation and Evaluation of a Pediatric Pain Education Program for Healthcare Providers in Ghana: A Multidisciplinary Approach. [PDF]

open access: yesPaediatr Neonatal Pain
ABSTRACT Pediatric pain remains one of the inadequately managed conditions in clinical practice, especially in low‐resource settings, due in part to limited training across health professions. Addressing this gap requires a coordinated, multidisciplinary approach to improve pain assessment and management in children.
Amponsah AK   +11 more
europepmc   +2 more sources

Hyperalgesic effect induced by barbiturates, midazolam and ethanol: pharmacological evidence for GABA-A receptor involvement

open access: yesBrazilian Journal of Medical and Biological Research, 1997
The involvement of GABA-A receptors in the control of nociception was studied using the tail-flick test in rats. Non-hypnotic doses of the barbiturates phenobarbital (5-50 mg/kg), pentobarbital (17-33 mg/kg), and thiopental (7.5-30 mg/kg), of the ...
M.A.K.F. Tatsuo   +5 more
doaj   +1 more source

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