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Basic &Clinical Pharmacology &Toxicology, Volume 132, Issue 1, Page 111-119, January 2023., 2023 Abstract Information regarding deaths caused by poisoning or adverse effects of medication in Danish persons not using illicit narcotic drugs (PNUIDs) is sparse. To characterize aetiology, demographics, and death scene, we reviewed all legal autopsies performed at Aarhus University from 2017 to 2019 and isolated 96 deaths caused by medications in ...
Charlotte U. Andersen +4 more
wiley +1 more source
New Methodology for the Synthesis of Thiobarbiturates Mediated by Manganese(III) Acetate
Molecules, 2012 A three step synthesis of various thiobarbiturate derivatives 17–24 was established. The first step is mediated by Mn(OAc)3, in order to generate a carbon-carbon bond between a terminal alkene and malonate.
Patrice Vanelle +2 more
doaj +1 more source
Frontiers in Pharmacology, 2023 Zulresso (brexanolone) is an aqueous formulation of the neurosteroid, allopregnanolone, and the only FDA-approved medication for the treatment of postpartum depression (PPD).
Alexander B. Horwitz +2 more
doaj +1 more source
Narcotics Addiction and Its Treatment [PDF]
, 1957 The ongoing mythologizing of the poet in both criticism and, as recently in a play produced by Wasa teater (Vasa), is reductive, and needs to be confronted.
Winick, Charles
core +4 more sources
Acta Crystallographica Section E: Crystallographic Communications, 2017 The molecule of buthalital, (I) [systematic name: 5-(2-methylpropyl)-5-(prop-2-en-1-yl)-2-sulfanylidene-1,3-diazinane-4,6-dione], C11H16N2O2S, exhibits a planar pyrimidine ring, whereas the pyrimidine ring of methitural, (II) [systematic name: 5-(1 ...
Thomas Gelbrich, Ulrich J. Griesser
doaj +1 more source
Barbiturates Bind in the GLIC Ion Channel Pore and Cause Inhibition by Stabilizing a Closed State*♦
Journal of Biological Chemistry, 2016 Barbiturates induce anesthesia by modulating the activity of anionic and cationic pentameric ligand-gated ion channels (pLGICs). Despite more than a century of use in clinical practice, the prototypic binding site for this class of drugs within pLGICs is
Z. Fourati +8 more
semanticscholar +1 more source
Acta Crystallographica Section E, 2014 The asymmetric unit of the title molecular salt, C3H10N+·C12H9N4O7− [alternative name: trimethylammonium 5-(2,4-dinitrophenyl)-1,3-dimethyl barbiturate], contains one anion and two half-occupancy cations.
Sridevi Gunaseelan +1 more
doaj +1 more source
Alcohol consumption in heroin users, methadone-substituted and codeine-substituted patients - Frequency and correlates of use [PDF]
, 2003 This retrospective study aims to determine whether there is a difference in the additional consumption of alcohol between addicts treated with methadone or dihydrocodeine (DHC) and untreated addicts injecting heroin.
Backmund, Markus +4 more
core +1 more source
Capacities of Follow-up of the Severity of Acute Barbiturate Intoxications and their Prediction
Общая реаниматология, 2005 Seventy-eight patients with moderate, severe, and fatal (n = 12) acute intoxication with barbiturates, as evidenced by the measurements of their blood concentrations were examined.
I. I. Vorobyeva +2 more
doaj +1 more source
Antibacterial, Antiurease, and Antioxidant Activities of Some Arylidene Barbiturates
Applied Biochemistry and Biotechnology, 2013 Some series of arylidene barbiturates and thiobarbiturates were evaluated for their antibacterial, antioxidant, and urease inhibition activities. The arylidene barbiturates and thiobarbiturates were tested for antimicrobial activity using the agar well ...
B. B. Sokmen +4 more
semanticscholar +1 more source