Results 21 to 30 of about 20,407 (174)
Archives of Academic Emergency Medicine, 2018 Introduction:Â Physicians frequently deal with procedures which require sedation of pediatric patients. Laceration repair is one of them. No study has been performed regarding the comparison between induction of sedation with sodium thiopental and ...
Reza Azizkhani +3 more
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Crystals, 2016 The crystal structure of the methanol hemisolvate of 5,5-dibromobarbituric acid (1MH) displays an H-bonded layer structure which is based on N–H∙∙∙O=C, N–H∙∙∙O(MeOH) and (MeOH)O–H∙∙∙O interactions.
Thomas Gelbrich +4 more
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Molecules, 2019 The wide abuse of barbiturates has aroused extensive public concern. Therefore, the determination of such drugs is becoming essential in therapeutic drug monitoring and forensic science.
Ruiqin Zhu +3 more
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Associations of Adverse Clinical Course and Ingested Substances among Patients with Deliberate Drug Poisoning: A Cohort Study from an Intensive Care Unit in Japan. [PDF]
PLoS ONE, 2016 Some patients with deliberate drug poisoning subsequently have an adverse clinical course. The present study aimed to examine whether the type of drugs ingested and psychiatric diagnoses were related to an adverse clinical course.We conducted a cohort ...
Kanako Ichikura +2 more
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Molecules, 2017 Widespread concern for the occurrence of resistant strains, along with the avoidance of the use of highly toxic insecticides and their wide environmental dispersal, highlights the need for the development of new and safer pest control agents.
Seon-Mi Seo +7 more
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Advanced Materials, EarlyView.A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade +19 more
wiley +1 more source
Guidelines for euthanasia of laboratory animals used in biomedical research [PDF]
Medicamentul Veterinar, 2012 Laboratory animals are used in several fields of science research, especially in biology, medicine and veterinary medicine. The majority of laboratory animals used in research are experimental models that replace the human body in study regarding ...
Adina Baias, +2 more
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Case report: Fatal poisoning caused by additive effects of two barbiturates
Frontiers in Pharmacology, 2023 A case of fatal poisoning involving multiple psychotropic drugs is presented. Quantitative toxicological analysis showed femoral blood concentrations of pentobarbital, phenobarbital, duloxetine, acetaminophen and tramadol were 10.39, 22.57, 0.22, 0.61 ...
Sella Takei +9 more
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Zuranolone: A case study in (regulatory) rush to judgement?
British Journal of Clinical Pharmacology, EarlyView.Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove +4 more
wiley +1 more source
Crystal structure of 5-hydroxy-5-propylbarbituric acid
Acta Crystallographica Section E: Crystallographic Communications, 2015 Molecules of the title compound, C7H10N2O4, systematic name 5-hydroxy-5-propylpyrimidine-2,4,6(1H,3H,5H)-trione, form a hydrogen-bonded framework which is based on three independent hydrogen bonds, N—H...O(carbonyl), N—H...O(hydroxy) and O—H...O(carbonyl)
Thomas Gelbrich, Ulrich J. Griesser
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