Results 31 to 40 of about 19,466 (148)

Hyperalgesic effect induced by barbiturates, midazolam and ethanol: pharmacological evidence for GABA-A receptor involvement

Brazilian Journal of Medical and Biological Research, 1997
The involvement of GABA-A receptors in the control of nociception was studied using the tail-flick test in rats. Non-hypnotic doses of the barbiturates phenobarbital (5-50 mg/kg), pentobarbital (17-33 mg/kg), and thiopental (7.5-30 mg/kg), of the ...
M.A.K.F. Tatsuo, C.M. Yokoro, J.V. Salgado, S.M.S. Pesquero, M.A.P. Santana, J.N. Francischi   +5 more
doaj   +1 more source

Rectal Thiopental versus Intramuscular Ketamine in Pediatric Procedural Sedation and Analgesia; a Randomized Clinical Trial

Archives of Academic Emergency Medicine, 2018
Introduction: Physicians frequently deal with procedures which require sedation of pediatric patients. Laceration repair is one of them. No study has been performed regarding the comparison between induction of sedation with sodium thiopental and ...
Reza Azizkhani, Mehrdad Esmailian, Azadeh shojaei, Keihan Golshani   +3 more
doaj   +1 more source

Associations of Adverse Clinical Course and Ingested Substances among Patients with Deliberate Drug Poisoning: A Cohort Study from an Intensive Care Unit in Japan. [PDF]

PLoS ONE, 2016
Some patients with deliberate drug poisoning subsequently have an adverse clinical course. The present study aimed to examine whether the type of drugs ingested and psychiatric diagnoses were related to an adverse clinical course.We conducted a cohort ...
Kanako Ichikura, Yasuyuki Okumura, Takashi Takeuchi   +2 more
doaj   +1 more source

The use of barbiturate-induced coma during cerebrovascular neurosurgery procedures: A review of the literature

Brain Circulation, 2015
Barbiturates are indicated for use during vascular neurosurgery procedures such as carotid surgery, arteriovenous malformation (AVM) surgery, cerebral aneurysm surgery, extracranial-intracranial bypass, and following significant bleeding due to AVMs or ...
Nathaniel R Ellens, Bryan E Figueroa, Justin C Clark   +2 more
doaj   +1 more source

Case report: Fatal poisoning caused by additive effects of two barbiturates

Frontiers in Pharmacology, 2023
A case of fatal poisoning involving multiple psychotropic drugs is presented. Quantitative toxicological analysis showed femoral blood concentrations of pentobarbital, phenobarbital, duloxetine, acetaminophen and tramadol were 10.39, 22.57, 0.22, 0.61 ...
Sella Takei, Hiroshi Kinoshita, Mostofa Jamal, Mitsuru Kumihashi, Tadayoshi Yamashita, Etsuko Tanaka, Sachiko Kawahara, Hiroko Abe, Kunihiko Tsutsui, Shoji Kimura   +9 more
doaj   +1 more source

Larvicidal and Nematicidal Activities of 3-Acylbarbituric Acid Analogues against Asian Tiger Mosquito, Aedes albopictus, and Pine Wood Nematode, Bursaphelenchus xylophilus

Molecules, 2017
Widespread concern for the occurrence of resistant strains, along with the avoidance of the use of highly toxic insecticides and their wide environmental dispersal, highlights the need for the development of new and safer pest control agents.
Seon-Mi Seo, Hyo-Rim Lee, Ji-Eun Lee, Yong-Chul Jeong, Hyung-Wook Kwon, Joon-Kwan Moon, Mark G. Moloney, Il-Kwon Park   +7 more
doaj   +1 more source

Noncovalent Synthesis of Topological Heterostructures Using a Site‐Selective Electrostatic Co‐Assembly Strategy

Angewandte Chemie International Edition, EarlyView.
A site‐selective electrostatic co‐assembly (SSECA) strategy was developed to fabricate a variety of topological heterostructures (THSs) with unprecedented architectures from two‐component systems of organometallic complexes and block copolymers. The THSs are composed of rigid parts of closely stacked organometallic complexes and flexible segments ...
Zhen Geng, Ki Ip, Priscilla Lok‐Yi Chiu, Eric Ka‐Ho Wong, Vivian Wing‐Wah Yam   +4 more
wiley   +1 more source

Acute cardiovascular effects associated with the use of prescription medications: A Danish nationwide screening study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim This study aims to conduct a hypothesis‐generating screening for acute cardiovascular effects of prescription medications. Methods This Danish nationwide screening study was conducted among incident cases of cardiovascular diseases, including myocardial infarction (MI), ischemic stroke (IS), heart failure (HF), venous thromboembolism (VTE),
Saad Hanif Abbasi, Lars Christian Lund, Jesper Hallas, Martin Thomsen Ernst, Anton Pottegård   +4 more
wiley   +1 more source

Crystal structure of 5-hydroxy-5-propylbarbituric acid

Acta Crystallographica Section E: Crystallographic Communications, 2015
Molecules of the title compound, C7H10N2O4, systematic name 5-hydroxy-5-propylpyrimidine-2,4,6(1H,3H,5H)-trione, form a hydrogen-bonded framework which is based on three independent hydrogen bonds, N—H...O(carbonyl), N—H...O(hydroxy) and O—H...O(carbonyl)
Thomas Gelbrich, Ulrich J. Griesser
doaj   +1 more source

α‐Azaaryl carbonyl derivatives in stereodivergent catalytic reactions

Bulletin of the Korean Chemical Society, EarlyView.
This review highlights recent progress in the catalytic synthesis of chiral azaarenes, focusing on α‐azaaryl carbonyl derivatives as versatile precursors. By leveraging chiral Lewis acid catalysis, stereodivergent reactions with diverse electrophiles enable precise construction of multi‐stereogenic azaarenes, offering new opportunities for advanced ...
Ilwoo Song, Byungjun Kim, Hooseung Lee, Sarah Yunmi Lee   +3 more
wiley   +1 more source