Results 61 to 70 of about 20,407 (174)

Wake‐promoting neuromodulators in Alzheimer's disease: Implications for sleep and brain clearance

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Neuromodulatory subcortical systems (NSS) regulate arousal, cognition, and sleep–wake transitions through widespread influence on cortical and subcortical networks. Increasing evidence links dysfunction of these systems to the pathogenesis of Alzheimer's disease (AD). Degeneration and dysregulation of NSS occurs during the preclinical phase of
Taylor J. Pedersen, Sabrina G. Clemens, Joseph R. Winer, Ashish Sharma, Neus Falgàs, Brendan P. Lucey, Brian A. Gordon, Erik S. Musiek   +7 more
wiley   +1 more source

Association Between Spinal Manipulation, Butalbital Prescription, and Medication Overuse Headache in Adults With Tension‐Type Headache: Retrospective Cohort Study

Health Science Reports
Background and Aims Butalbital is an acute headache medication commonly prescribed for tension‐type headache (TTH), although discouraged by guidelines due to a risk of medication overuse headache (MOH).
Robert J. Trager, Timothy J. Williamson, Pratheek S. Makineni, Lindsay H. Morris   +3 more
doaj   +1 more source

Evolution of Pharmacologic Induction of Burst Suppression in Adult TBI: Barbiturate Coma Versus Modern Sedatives

Clinical and Translational Neuroscience
Background: Severe traumatic brain injury (TBI) often leads to elevated intracranial pressure (ICP) that requires aggressive management. Inducing burst suppression with deep sedation is an established therapy for refractory intracranial hypertension ...
Đula Đilvesi, Teodora Tubić, Sanja Maričić Prijić, Jagoš Golubović   +3 more
doaj   +1 more source

Integration of thin layer chromatography and smartphone-based colorimetric analysis for the detection of barbiturates

Green Analytical Chemistry
Barbiturates, a key class of psychoactive drugs, present challenges in accurate detection due to their misuse and involvement in forensic investigations.
Keneuoe Letumanyane, Elisa Kalugendo
doaj   +1 more source

Safety of MRI Examinations Under Sedation: A Nationwide Survey in Japan

Journal of Magnetic Resonance Imaging, Volume 63, Issue 3, Page 798-810, March 2026.
ABSTRACT Background MRI is performed under sedation for patients requiring immobility or for those already sedated for clinical management. Although specialist guidelines advocate for anesthesiologist‐led care, non‐anesthesiologist‐led adult sedation is a common practice worldwide. Furthermore, the increase in risk attributable to sedation has not been
Shiori Amemiya, Masako Kataoka, Tsukasa Doi, Toshinori Hirai, Takayuki Obata, Kagayaki Kuroda   +5 more
wiley   +1 more source

A Rapid and Sensitive Method for the Determination of Chitosan Concentration by NMR Relaxometry

Magnetic Resonance in Chemistry, Volume 64, Issue 3, Page 257-264, March 2026.
ABSTRACT A rapid, reagent‐free method for the quantification of chitosan in aqueous solutions was developed using 1H nuclear magnetic resonance (NMR) relaxometry. Transverse relaxation times (T2) of chitosan solutions (5–1000 mg/L) were measured with a Carr–Purcell–Meiboom–Gill (CPMG) sequence on a benchtop NMR relaxometer.
Marta Férová, Jiří Kalina
wiley   +1 more source

Real‐World Pharmacological Management of Alcohol Dependence in a Nepalese Rehabilitation Center: Prospective Cohort Study

Public Health Challenges, Volume 5, Issue 1, March 2026.
This prospective cohort study demonstrates that structured, evidence‐informed pharmacological management significantly reduced alcohol withdrawal severity and improved liver enzyme profiles among alcohol dependence patients in a Nepalese rehabilitation center, supporting the implementation of standardized treatment protocols in resource‐limited ...
Sanjay Singh, Nirmal Raj Marasine, Sabina Sankhi, Kabita Bhandari, Gajendra Bahadur Bhuju   +4 more
wiley   +1 more source

Anesthetic Strategies for Closed Reduction of Dislocated Total Hip Arthroplasty: A Scoping Review

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 3, March 2026.
ABSTRACT Background Total hip arthroplasty (THA) is a frequently performed orthopedic procedure, with dislocation being a common complication, often requiring closed reduction. Anesthetic strategies for this vary, and evidence on the efficacy, safety, and cost‐effectiveness of current strategies is limited.
Rasmus Linnebjerg Knudsen, Rikke Helene Frølund Bjulf, Aurelien‐Xuan Rosendal Bahuet, Mathias Therkel Steensbæk, Anne‐Sofie Linde Jellestad, Kai Henrik Wiborg Lange, Lars Hyldborg Lundstrøm, Anders Kehlet Nørskov   +7 more
wiley   +1 more source

Drug Use After Emergency Department‐Initiated Injectable Buprenorphine: A Secondary Analysis of the ED‐INNOVATION Ancillary Safety and Feasibility Trial

Academic Emergency Medicine, Volume 33, Issue 3, March 2026.
ABSTRACT Study Objective To characterize opioid and nonopioid drug use in the week following emergency department (ED)‐initiated extended‐release buprenorphine (XR‐BUP) treatment using both self‐reported data and urine drug screens (UDS). Methods This study uses data collected during a nonrandomized clinical trial of patients with untreated opioid use ...
Ethan Cowan, Gail D'Onofrio, Jeanmarie Perrone, Erik Anderson, James Dziura, Kathryn Hawk, Andrew Herring, Ryan McCormack, Manali Phadke, Elizabeth A. Samuels, David A. Fiellin   +10 more
wiley   +1 more source

Evaluation of the Enhanced Recovery After Surgery (ERAS) Guidance for Patients With Spinal Metastasis

Orthopaedic Surgery, Volume 18, Issue 3, Page 385-401, March 2026.
The flow diagram of study. ABSTRACT Surgery continues to remain the most effective treatment for spinal metastasis (SM). As the number of surgeries continues to grow, the need for consensus guidelines for optimal perioperative care is imperative. Enhanced recovery after surgery (ERAS) protocols were created for this purpose. The objective of this study
Fanjie Li, Wenlong Yu, Changchang Shen, Jinxin Luo, Zhibin Li, Qiang Gao, Chengchun Jin, Tao Li, Quan Huang, Shuqiang Wang, Peilin Chu, Mengchen Yin   +11 more
wiley   +1 more source