Results 61 to 70 of about 66,176 (317)

Drug‐facilitated crime: A review of findings between 2019 and 2023

Journal of Forensic Sciences, EarlyView.
Abstract Drug‐facilitated crime (DFC) is a criminal act (e.g., assault, robbery, or sexual assault) in which the perpetrator uses drugs to impair the victim's ability to resist, remember, or recognize the crime being committed. Ethanol is commonly implicated in DFC casework, but limited data are published on other substances currently implicated in ...
Meaghan R. Hessler, Sherri L. Kacinko, Barry K. Logan   +2 more
wiley   +1 more source

Fatal drug overdoses in healthcare workers: A thematic framework analysis of coroner reports

Addiction, EarlyView.
Abstract Background and aims Healthcare workers face specific vulnerabilities for drug overdose due to their unique access to medications, clinical knowledge and work‐related stress. This study aimed to understand the characteristics of fatal overdoses in healthcare workers with a view to providing guidance for preventative strategies.
Thikra Algahtani, Siobhan Gee, Aminah Shah, Bryn D. Williams, Hayley C. Gorton, Sarah Welch, Caroline S. Copeland   +6 more
wiley   +1 more source

Epilepsy and Psychiatric Comorbidities: Drug Selection. [PDF]

, 2017
Purpose of review The pharmacological treatment of patients with epilepsy and psychiatric comorbidities may sometimes represent a therapeutic challenge.
A Thapar, AB Ettinger, AK Ngugi, AM Kanner, B Pohlmann-Eden, BK MacDonald, C Adelow, C Reilly, CJ Wotton, D Rai, DC Hesdorffer, DC Hesdorffer, DC Hesdorffer, DW Dunn, FG Gilliam, H Feldman, H Hamid, HM Boer de, J Gonzalez-Heydrich, J Hovorka, J-G Seo, JD Leander, JF Tellez-Zenteno, JR White, JS Duncan, JS Markowitz, JW Sander, K Alper, K Davison, K Santos, L Forsgren, LG Kiloh, LJ Stephen, LK Fung, LM Specchio, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, Marco Mula, MJ Brodie, MM Robertson, MP Kerr, MS Thomé-Souza, O Devinsky, OC Cockerell, P Perucca, R Kuhn, R Nabbout, R Tuchman, R Tuchman, RS Fisher, S Varma, SJ Gill, SR Pliszka, SV Pacia, T Nickl-Jockschat, Y-T Chang   +68 more
core   +1 more source

Rectal Thiopental versus Intramuscular Ketamine in Pediatric Procedural Sedation and Analgesia; a Randomized Clinical Trial

Emergency, 2015
Introduction: Physicians frequently deal with procedures which require sedation of pediatric patients. Laceration repair is one of them. No study has been performed regarding the comparison between induction of sedation with sodium thiopental and ...
Reza Azizkhani, Mehrdad Esmailian, Azadeh shojaei, Keihan Golshani   +3 more
doaj  

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

Can the large language model ChatGPT‐4omni predict outcomes in adult patients with status epilepticus?

Epilepsia, Volume 66, Issue 3, Page 674-685, March 2025.
Abstract Objective Large language models (LLMs) have recently gained attention for clinical decision‐making and diagnosis. This study evaluates the performance of the recently updated LLM Chat Generative Pre‐Trained Transformer‐4omni (ChatGPT‐4o) in predicting clinical outcomes in patients with status epilepticus and compares its prognostic performance
Simon A. Amacher, Sira M. Baumann, Sebastian Berger, Armon Arpagaus, Simon B. Egli, Pascale Grzonka, Paulina S. C. Kliem, Sabina Hunziker, Urs Fisch, Caroline E. Gebhard, Raoul Sutter   +10 more
wiley   +1 more source

Neurotransmitter-gated ion channels at fast chemical synapses: from structure to pathology [PDF]

, 2005
Fil: Bouzat, Cecilia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur.
Bouzat, Cecilia Beatriz
core  

Status epilepticus in older adults: A critical review

Epilepsia, EarlyView.
Abstract Older adults (≥60 years of age) have the highest incidence of status epilepticus (SE) among adults and experience the highest morbidity and mortality. SE incidence increases with age in adulthood. A recent study from Austria estimated an incidence of 89.6/100 000 and 67.6/100 000 person‐years adjusted for age and sex in women and men aged >60 ...
Matthew R. Woodward, Michael J. Armahizer, Tina I. Wang, Neeraj Badjatia, Emily L. Johnson, Emily J. Gilmore   +5 more
wiley   +1 more source

Enlarged cerebrospinal fluid spaces in opiate-dependent male patients: A stereological CT study [PDF]

, 1998
Computed tomography was performed in 9 male patients with a diagnosis of opiate dependence and in 9 age-matched psychiatric controls (neurotic depression).
Broich, Karl, Brömel, Thomas, Danos, Peter, Kasper, Siegfried, Krappel, Christian, Möller, Hans-Jürgen, Solymosi, Lazslo, Van Roos, Dirk   +7 more
core   +1 more source

Phenobarbital as an adjunctive agent for sedation in pediatric intensive care unit patients: A single-center, retrospective study from Colorado

Journal of Pediatric Critical Care
Background: Pediatric patients require pharmacological management of pain and agitation associated with mechanical ventilation. Pain and agitation may be refractory to opioids and alpha-2 agonists, prompting the use of adjunctive analgesics and sedatives
Kelli Jo Welter, Mackenzie N. DeVine, Sharon E. Gordon, Gina Demasellis   +3 more
doaj   +1 more source