Results 61 to 70 of about 48,209 (275)

Rectal Thiopental versus Intramuscular Ketamine in Pediatric Procedural Sedation and Analgesia; a Randomized Clinical Trial

Emergency, 2015
Introduction: Physicians frequently deal with procedures which require sedation of pediatric patients. Laceration repair is one of them. No study has been performed regarding the comparison between induction of sedation with sodium thiopental and ...
Reza Azizkhani, Mehrdad Esmailian, Azadeh shojaei, Keihan Golshani   +3 more
doaj  

Epilepsy and Psychiatric Comorbidities: Drug Selection. [PDF]

, 2017
Purpose of review The pharmacological treatment of patients with epilepsy and psychiatric comorbidities may sometimes represent a therapeutic challenge.
A Thapar, AB Ettinger, AK Ngugi, AM Kanner, B Pohlmann-Eden, BK MacDonald, C Adelow, C Reilly, CJ Wotton, D Rai, DC Hesdorffer, DC Hesdorffer, DC Hesdorffer, DW Dunn, FG Gilliam, H Feldman, H Hamid, HM Boer de, J Gonzalez-Heydrich, J Hovorka, J-G Seo, JD Leander, JF Tellez-Zenteno, JR White, JS Duncan, JS Markowitz, JW Sander, K Alper, K Davison, K Santos, L Forsgren, LG Kiloh, LJ Stephen, LK Fung, LM Specchio, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, M Mula, Marco Mula, MJ Brodie, MM Robertson, MP Kerr, MS Thomé-Souza, O Devinsky, OC Cockerell, P Perucca, R Kuhn, R Nabbout, R Tuchman, R Tuchman, RS Fisher, S Varma, SJ Gill, SR Pliszka, SV Pacia, T Nickl-Jockschat, Y-T Chang   +68 more
core   +1 more source

Abietic Acid Enhances the Sedative Activity of Diazepam: In vivo Approach along with Receptor Binding Affinity and Molecular Interaction with the GABAergic System

ChemistryOpen, EarlyView.
Abietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Meher Afroz, Rubel Hasan, Mst Muslima Khatun, Mokammel Hossain Tito, Md Shadin, Ranjit Chakma, Mohammed Asiri, Faisal H. Altemani, Abdullah H. Altemani, Md Shimul Bhuia, Muhammad Torequl Islam   +10 more
wiley   +1 more source

Phenobarbital as an adjunctive agent for sedation in pediatric intensive care unit patients: A single-center, retrospective study from Colorado

Journal of Pediatric Critical Care
Background: Pediatric patients require pharmacological management of pain and agitation associated with mechanical ventilation. Pain and agitation may be refractory to opioids and alpha-2 agonists, prompting the use of adjunctive analgesics and sedatives
Kelli Jo Welter, Mackenzie N. DeVine, Sharon E. Gordon, Gina Demasellis   +3 more
doaj   +1 more source

Recent Advances in Homogeneous Catalysis with Platinum Group Pincer Complexes: Hydrogen‐Mediated Transformations and Cross‐Coupling Reactions

The Chemical Record, EarlyView.
Platinum group pincer complexes are highly efficient catalysts. Additionally, their high activity enables challenging transformations with low catalyst loading. Herein, we summarize the most relevant advances of catalysis involving platinum group pincer complexes. The use of pincer complexes based on platinum group metals is undoubtedly one of the most
Juan S. Serrano‐García, Andrés Amaya‐Flórez, Jordi R.‐Galindo, Adrián Ruíz‐Martínez, David Morales‐Morales   +4 more
wiley   +1 more source

Drug Use After Emergency Department‐Initiated Injectable Buprenorphine: A Secondary Analysis of the ED‐INNOVATION Ancillary Safety and Feasibility Trial

Academic Emergency Medicine, EarlyView.
ABSTRACT Study Objective To characterize opioid and nonopioid drug use in the week following emergency department (ED)‐initiated extended‐release buprenorphine (XR‐BUP) treatment using both self‐reported data and urine drug screens (UDS). Methods This study uses data collected during a nonrandomized clinical trial of patients with untreated opioid use ...
Ethan Cowan, Gail D'Onofrio, Jeanmarie Perrone, Erik Anderson, James Dziura, Kathryn Hawk, Andrew Herring, Ryan McCormack, Manali Phadke, Elizabeth A. Samuels, David A. Fiellin   +10 more
wiley   +1 more source

The Value of Ultrasonography in determining Pupillary Light Reflex in Patients with Traumatic Ocular Injuries; a Letter to Editor

Archives of Academic Emergency Medicine, 2019
Pupillary light reflex (PLR) measurement is one of the frequent physical examinations used by emergency physicians for assessment of brain stem function and monitoring of intracranial pressure (1, 2).
Hamid Mirjalili, Ali Raee Ezzabadi, Yeganeh Yazdiyousefi, Mohammad Ali Jafari Nadoshan   +3 more
doaj   +1 more source

Etiology and Management of Sexual Dysfunction [PDF]

, 2009
Sexual dysfunction is the impairment or disruption of any of the three phases of normal sexual functioning, including loss of libido, impairment of physiological arousal and loss, delay or alteration of orgasm.
Bevinahalli Nanjegowda, Raveesh, Muthugaduru Shivarudrappa, Narendra Kumar, Mysore Nagaraj, Anil Kumar, Pai, Nagesh Brahmavar, Rajagopal, Rajendra, Siddika, Nayeema   +5 more
core   +2 more sources

Sedative-like effect of intraperitoneal GABA administration in the open field test [PDF]

, 2016
Gamma-Amino Butyric Acid (GABA) is the main inhibitor neurotransmitter of the Central Nervous System (CNS). Its peripheral administration has been matter of discussion. On the one hand, it has been reported that it does not cross the Blood-Brain Barrier (
Gargiulo, Augusto Pascual Ítalo, Gargiulo, Pascual Angel, Guevara, Manuel Alejandro, Lafuente, José Vicente, Landa, Adriana Inés, Marquez Herrero, Santiago, Mesones, Humberto Luis, Romanowicz, Esteban Alejandro   +7 more
core   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source