Results 81 to 90 of about 64,838 (318)

Phenobarbital as an adjunctive agent for sedation in pediatric intensive care unit patients: A single-center, retrospective study from Colorado

open access: yesJournal of Pediatric Critical Care
Background: Pediatric patients require pharmacological management of pain and agitation associated with mechanical ventilation. Pain and agitation may be refractory to opioids and alpha-2 agonists, prompting the use of adjunctive analgesics and sedatives
Kelli Jo Welter   +3 more
doaj   +1 more source

Synthesis, X-Ray Crystal Structures, Biological Evaluation, and Molecular Docking Studies of a Series of Barbiturate Derivatives

open access: yesJournal of Chemistry, 2016
A series of barbiturates derivatives synthesized and screened for different set of bioassays are described. The molecular structures of compounds 5a, 5d, and 5f were solved by single-crystal X-ray diffraction techniques. The results of bioassay show that
Assem Barakat   +9 more
doaj   +1 more source

Epidemiology of overdose episodes from the period prior to hospitalization for drug poisoning until discharge in Japan: An exploratory descriptive study using a nationwide claims database

open access: yesJournal of Epidemiology, 2017
Background: Little is known about the nationwide epidemiology of the annual rate, causative substance, and clinical course of overdose-related admission.
Yasuyuki Okumura
doaj   +1 more source

Cost‐Effective Nanosensor Solutions for Ultra‐Sensitive Detection of Metronidazole

open access: yesAnalytical Science Advances, Volume 6, Issue 1, June 2025.
ABSTRACT Metronidazole (MNZ) is a widely used imidazole antibiotic effective against bacterial and protozoal infections, including giardiasis, trichomoniasis, bacterial vaginosis, and antibiotic‐associated colitis. However, prolonged and excessive use of MNZ can lead to serious side effects, such as peripheral neuropathies, toxicity, and optic ...
Ahmad Mobed   +6 more
wiley   +1 more source

Presumptive Tests for Xylazine—A Computer Vision Approach

open access: yesAnalytical Science Advances, Volume 6, Issue 1, June 2025.
ABSTRACT Abuse of xylazine is an immediate global public health concern. We report the distinct and measurable colour changes when xylazine is exposed to the Mandelin, Marquis and Mecke presumptive test reagents. The colour changes observed with xylazine are distinct from those of drugs that give colour changes from the same presumptive tests.
Hui Yun Chang   +6 more
wiley   +1 more source

Antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID)

open access: yesVeterinary Dermatology, Volume 36, Issue 3, Page 234-282, June 2025.
Background – Canine pyoderma is one of the most common presentations in small animal practice, frequently leading to antimicrobial prescribing. Objectives – To provide clinicians with antimicrobial treatment guidelines for staphylococcal pyoderma, including those involving meticillin‐resistant staphylococci.
Anette Loeffler   +9 more
wiley   +1 more source

Potentiometric measurement of barbituric acid by integration of supramolecular receptors into ChemFETs

open access: yesSensing and Bio-Sensing Research, 2021
Potentiometric sensing devices were prepared based on ion-selective membranes (ISM) containing Hamilton-type receptors incorporated into polymer membranes.
Grace M. Kuhl   +4 more
doaj  

Biofeedback in the prophylactic treatment of medication overuse headache: a pilot randomized controlled trial [PDF]

open access: yes, 2016
Background: Medication overuse headache (MOH) is a major clinical concern and a common health risk. Recent literature stressed the need to manage chronic headache by using integrated biobehavioral approaches.
Cevoli, Sabina   +6 more
core   +1 more source

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