Results 51 to 60 of about 64,997 (303)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada +6 more
wiley +1 more source
, 2009 Nucleotide excision repair (NER) is responsible for repairing bulky helix-distorting DNA lesions and is essential for the maintenance of genomic integrity.
Mathers, John +6 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Bisphenol a promotes cell survival following oxidative DNA damage in mouse fibroblasts.
PLoS ONE, 2015 Bisphenol A (BPA) is a biologically active industrial chemical used in production of consumer products. BPA has become a target of intense public scrutiny following concerns about its association with human diseases such as obesity, diabetes ...
Natalie R Gassman +6 more
doaj +1 more source
Base excision DNA repair and cancer
Oncotarget, 2014 Transformed cells can develop drug resistance via repair mechanisms that counteract the DNA damage from chemotherapy or radiation therapy. Disruption of DNA repair pathways can cause mis-repair that is cytotoxic [1]. Specific DNA repair inhibitors might thus be combined with DNA-damaging agents for improved therapy.
Tell, G, Demple B
openaire +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Base excision repair in Alzheimer’s disease
Postępy Higieny i Medycyny Doświadczalnej, 2014 Alzheimer's disease (AD) is the most common neurodegenerative disease in people over 65 years of age. Estimates indicate that about 200 thousand Pole suffer from AD while in the world about 30 million people. Forecasts show that in developed countries the number of people with neurodegenerative diseases by 2025 will increase by several hundred percent ...
Dominik, Kwiatkowski, Tomasz, Sliwiński
openaire +2 more sources
The relationship between DNA damage and repair and the occurrence and development of disease
Frontiers in GeneticsDNA damage can lead to the development of diseases such as tumors. To counteract this, organisms have evolved various repair mechanisms targeting different types of damage.
Chongbing Sun +4 more
doaj +1 more source
Overexpression of associated with altered genome and poor survival in selected types of human cancer
Tumor Biology, 2020 Base excision repair, which is initiated by the DNA N -glycosylase proteins, is the frontline for repairing potentially mutagenic DNA base damage. Several base excision repair genes are deregulated in cancer and affect cellular outcomes to chemotherapy ...
Oanh TN Tran +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source