Results 231 to 240 of about 2,847,295 (322)

BEscreen: a versatile toolkit to design base editing libraries. [PDF]

Nucleic Acids Res
Schneider PG, Liu S, Bullinger L, Ostendorf BN.   +3 more
europepmc   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Identification and characterization of shifted G•U wobble pairs resulting from alternative protonation of RNA. [PDF]

Nucleic Acids Res
Saon MS, Douds CA, Veenis AJ, Pearson AN, Yennawar NH, Bevilacqua PC.   +5 more
europepmc   +1 more source

An evolutionary tree relating eight alphaviruses, based on amino-terminal sequences of their glycoproteins.

, 1984
JOHN R. BELL, Richard M. Kinney, Dennis W. Trent, Ellen G. Strauss, James H. Strauss   +4 more
openalex   +1 more source

Species-specific uptake of DNA by gonococci is mediated by a 10-base-pair sequence [PDF]

, 1991
Christopher A. Elkins, Christopher Thomas, H. Steven Seifert, P. Frederick Sparling   +3 more
openalex   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Hyperchaotic color image encryption using eight-base DNA complementary rules and extended Zigzag transform. [PDF]

PLoS One
Yang B.
europepmc   +1 more source

SixSchizosaccharomyces pombetRNA genes including a gene for a tRNA^Lyswith an intervening sequence which cannot base-pair with the anticodon

, 1983
Vera Gamulin, Jen-i Mao, Bernd Appel, Martin Sumner-Smith, Fumiaki Yamao, Dieter Söll   +5 more
openalex   +2 more sources

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Precise mapping of single-stranded DNA breaks by sequence-templated erroneous DNA polymerase end-labelling. [PDF]

Nat Commun
Wenson L, Heldin J, Martin M, Erbilgin Y, Salman B, Sundqvist A, Schaal W, Sandbaumhüter FA, Jansson ET, Chen X, Davidsson A, Stenerlöw B, Espinoza JA, Lindström M, Lennartsson J, Spjuth O, Söderberg O.   +16 more
europepmc   +1 more source