Results 81 to 90 of about 2,107,603 (337)
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
Advanced Biology, EarlyView.This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim +3 more
wiley +1 more source
Expert guidelines for the management of Alport syndrome and thin basement membrane nephropathy.
Journal of the American Society of Nephrology, 2013 Few prospective, randomized controlled clinical trials address the diagnosis and management of patients with Alport syndrome or thin basement membrane nephropathy.
J. Savige +5 more
semanticscholar +1 more source
Renal basement membrane components [PDF]
Kidney International, 1999 Renal basement membrane components. Basement membranes are specialized extracellular matrices found throughout the body. They surround all epithelia, endothelia, peripheral nerves, muscle cells, and fat cells. They play particularly important roles in the kidney, as demonstrated by the fact that defects in renal basement membranes are associated with ...
openaire +3 more sources
The Mayo Clinic consensus report on membranous nephropathy; a promising step toward better treating the disease [PDF]
Journal of NephropharmacologyMembranous nephropathy is an immune complex disease caused by subepithelial deposits. The pathological manifestations of membranous nephropathy are considered by the creation of immune complexes in the epithelial cells of the glomerular basement membrane.
Samaneh Zandifar +3 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong +7 more
wiley +1 more source
The corneal epithelial basement membrane: structure, function, and disease.
Investigative Ophthalmology and Visual Science, 2013 The corneal epithelial basement membrane (BM) is positioned between basal epithelial cells and the stroma. This highly specialized extracellular matrix functions not only to anchor epithelial cells to the stroma and provide scaffolding during embryonic ...
A. Torricelli +3 more
semanticscholar +1 more source
LAMININ-5. A POTENTIAL TOOL IN DIAGNOSIS OF HEAD AND NECK SQUAMOUS CELL CARCINOMA
Zdravniški Vestnik, 2002 The heterotrimeric extracellular matrix protein laminin-5 (ln-5) is a regular constituent of the basement membrane in oral and pharyngeal mucosa consisting of the α 3, β 3 and γ 2 chain.
Hartwig Kosmehl +3 more
doaj
Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects
Advanced Functional Materials, EarlyView.Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu +6 more
wiley +1 more source
Secrets of the Cutaneous Basement Membrane [PDF]
Journal of Investigative Dermatology, 2014 The paper in this issue by Has and co-workers reports 15 non-Herlitz epidermolysis bullosa patients with the same single amino-acid substitution in collagen XVII, all of whom presented with clinical and pathological features resembling Kindler syndrome.
openaire +3 more sources
Organ Length Control by an ADAMTS Extracellular Protease in Caenorhabditis elegans
G3: Genes, Genomes, Genetics, 2016 MIG-17, a secreted protease of the ADAMTS family, acts in the directed migration of gonadal distal tip cells (DTCs) through regulation of the gonadal basement membrane in Caenorhabditis elegans.
Yukimasa Shibata +7 more
doaj +1 more source