Results 1 to 10 of about 148,677 (158)

Overexpression of HLH4 Inhibits Cell Elongation and Anthocyanin Biosynthesis in Arabidopsis thaliana

Cells, 2022
In plants, many basic helix-loop-helix (bHLH) transcription factors are involved in controlling cell elongation. Three bHLH proteins, PACLOBTRAZOL RESISTANCE1 (PRE1), Cryptochrome Interacting Basic Helix-loop-helix 5 (CIB5), and Arabidopsis ILI1 binding ...
Quancan Hou, Wei Zhao, Lu Lu, Linlin Wang, Tianye Zhang, Binbin Hu, Tingwei Yan, Yuchen Qi, Fan Zhang, Nan Chao, Dorothea Bartels, Xiangyuan Wan   +11 more
doaj   +1 more source

Genome-Wide Identification of Apple Atypical bHLH Subfamily PRE Members and Functional Characterization of MdPRE4.3 in Response to Abiotic Stress

Frontiers in Genetics, 2022
Paclobutrazol Resistance (PRE) genes encode atypical basic helix–loop–helix (bHLH) transcription factor family. Typical bHLH proteins contain a bifunctional structure with a basic region involved in DNA binding and an adjacent helix–loop–helix domain ...
Tong Li, Yan Shi, Baihui Zhu, Tianen Zhang, Ziquan Feng, Xiaofei Wang, Xiuming Li, Chunxiang You   +7 more
doaj   +1 more source

Initial assessment of Id protein antagonist (aHLH) shows anti-proliferative activity on HEK293T, LS174T and HCT116 cells

Scientific African, 2022
Id proteins (1–4) which are dominant-negative antagonists of the basic helix-loop-helix (bHLH) family of transcription factors function in a variety of cellular processes.
Foster Kyei
doaj   +1 more source

The divergence between T cell and innate lymphoid cell fates controlled by E and Id proteins

Frontiers in Immunology, 2022
T cells develop in the thymus from lymphoid primed multipotent progenitors or common lymphoid progenitors into αβ and γδ subsets. The basic helix-loop-helix transcription factors, E proteins, play pivotal roles at multiple stages from T cell commitment ...
Aneta Pankow, Aneta Pankow, Xiao-Hong Sun, Xiao-Hong Sun, Xiao-Hong Sun   +4 more
doaj   +1 more source

Influence of S100A2 in Human Diseases

Diagnostics, 2022
S100 proteins are a family of low-molecular-weight proteins characterized by two calcium-binding sites with a helix-loop-helix (“EF-hand-type”) domain.
Hitomi Sugino, Yu Sawada
doaj   +1 more source

Inhibitor of DNA binding proteins revealed as orchestrators of steady state, stress and malignant hematopoiesis

Frontiers in Immunology, 2022
Adult mammalian hematopoiesis is a dynamic cellular process that provides a continuous supply of myeloid, lymphoid, erythroid/megakaryocyte cells for host survival.
Shweta Singh, Tanmoy Sarkar, Brad Jakubison, Brad Jakubison, Stephen Gadomski, Andrew Spradlin, Kristbjorn O. Gudmundsson, Kristbjorn O. Gudmundsson, Jonathan R. Keller, Jonathan R. Keller   +9 more
doaj   +1 more source

Atoh8 in Development and Disease

Biology, 2022
Atoh8 belongs to a large superfamily of transcriptional regulators called basic helix-loop-helix (bHLH) proteins. bHLH proteins have been identified in a wide range of organisms from yeast to humans.
Satya Srirama Karthik Divvela, Darius Saberi, Beate Brand-Saberi   +2 more
doaj   +1 more source

Genome Wide Identification and Characterization of Apple bHLH Transcription Factors and Expression Analysis in Response to Drought and Salt Stress [PDF]

, 2017
The bHLH (basic helix-loop-helix) transcription factor family is the second largest in plants. It occurs in all three eukaryotic kingdoms, and plays important roles in regulating growth and development.
Changhai Liu, Chao Li, Fengwang Ma, Ke Mao, Qinglong Dong   +4 more
core   +1 more source

MD investigation on the binding of microphthalmia-associated transcription factor with DNA

Journal of Saudi Chemical Society, 2022
As a main regulator of melanocyte development and an key melanoma oncogene, microphthalmia-associated transcription factor (MITF) is one of the proteins in the basic helix-loop-helix zipper (bHLHZip) transcription factor family. The study on the detailed
Xiang-Feng Wang, Jian Sun, Xin-Lu Wang, Jia-Kun Tian, Zhen-Wei Tian, Ji-Long Zhang, Ran Jia   +6 more
doaj   +1 more source

Identification and Expression Analysis of the bHLH Gene Family Members in Diospyros kaki

Horticulturae, 2023
Basic helix–loop–helix (bHLH) proteins belong to one of the largest families involved in plant growth, development, signal transduction, and secondary metabolism.
Weijuan Han, Qi Zhang, Yujing Suo, Huawei Li, Songfeng Diao, Peng Sun, Lin Huang, Jianmin Fu   +7 more
doaj   +1 more source