Results 91 to 100 of about 113,312 (290)

Autologous Extracellular Matrix‐Based Cell‐Free Therapy for Tissue Regeneration Through Trem2+ Macrophages Mediated Angiogenesis

Exploration, EarlyView.
ADF is prepared as a cell‐free bio‐membrane from autologous adipose ECM using simple physical techniques inspired by “papermaking”. It boasts superior properties and facilitates tissue regeneration through Trem2+ macrophages‐mediated angiogenesis. ADF can be stored long‐term for personalized medicine, offering insights into autologous ECM preservation ...
Mengmeng Hou, Nini Shi, Yajie Guo, Jiezhang Tang, Han Peng, Baoyan Liang, Yixuan Yu, Chenggang Yi, Huichen Li   +8 more
wiley   +1 more source

Unveiling CLC as a Central Regulator of Allergic Rhinitis via the CLC‐CCL26/POSTN Axis: An Integrated Bioinformatics and Experimental Study

Flavour and Fragrance Journal, EarlyView.
We unveil that CLC orchestrates the dual role of eosinophil recruitment via CCL26 and tissue remodelling via POSTN in allergic rhinitis, identifying it as a potential therapeutic target. ABSTRACT Allergic rhinitis (AR) is a chronic airway inflammation driven by a type 2 immune response, yet the molecular mechanisms underlying its persistence and tissue
Fanyu Yuan, Yuhan Dong, Zishuo Guo, Xiaodong Zhao, Jian Liu, Fangyuan Zhu, Shengjie Ge, Chengcheng Liu, Shuai Xu, Ming Xia   +9 more
wiley   +1 more source

THE HEMIC BASOPHIL [PDF]

Journal of Experimental Medicine, 1920
1. The basophilic granule of blood and marrow cells does not show the brown color reaction with benzidine solutions that is characteristic of the neutrophilic and eosinophilic granules. It differs from these types also in other important microchemical and physical particulars. 2.
openaire   +2 more sources

Novel birch pollen specific immunotherapy formulation based on contiguous overlapping peptides. [PDF]

, 2013
BACKGROUND: Synthetic contiguous overlapping peptides (COPs) may represent an alternative to allergen extracts or recombinant allergens for allergen specific immunotherapy.
Audran, R., Barbier, N., Boudousquié, C., Corradin, G., Pellaton, C., Perrin, Y., Reymond, C., Spertini, F., Thierry, A.C., Wassenberg, J.   +9 more
core   +1 more source

A Machine Learning Model Based on Blood Indices for the Differential Diagnosis of Colorectal Cancer and Colorectal Polyps

iLABMED, EarlyView.
This diagram systematically sorts out the complete data processing pipeline, clearly presenting the key links and logical connections from raw data collection, preprocessing (including cleaning, deduplication, format standardization, etc.), and core computational analysis to the result output.
Wenhui Yan, Lin Zhu, Hongming Wei, Jie Feng, Yanhong Gao   +4 more
wiley   +1 more source

Thymic stromal lymphopoietin-activated basophil promotes lung inflammation in mouse atopic march model

Frontiers in Immunology
BackgroundAtopic dermatitis (AD), a prevalent inflammatory skin disease affecting 10%-20% of the population, is linked to the development of asthma through atopic march (AM).
Xu Li, Zizhuo Li, Mindan Tang, Kaoyuan Zhang, Kaoyuan Zhang, Kaoyuan Zhang, Ting Yang, Weilong Zhong, Bo Yu, Bo Yu, Bo Yu, Fang Wang, Xia Dou, Xia Dou, Xia Dou   +14 more
doaj   +1 more source

Basophils and Eosinophils in Nematode Infections

Frontiers in Immunology, 2020
Helminths remain one of the most prolific pathogens in the world. Following infection helminths interact with various epithelial cell surfaces, including skin, lung, and gut.
Kazushige Obata-Ninomiya, Phillip P. Domeier, Steven F. Ziegler, Steven F. Ziegler   +3 more
doaj   +1 more source

The Immunological Correlation With Adenoid Hypertrophy and Allergic Rhinitis in Children

iNew Medicine, EarlyView.
The imbalance of Th1/Th2 and Th17/Treg cells in allergen and inflammatory responses might be associated with the development of adenoid hypertrophy, suggesting that allergic rhinitis maybe the risk factor of AH and providing a potential alternative explanation for adenoid hypertrophy pathogenesis.
Yang Song, Chao Zhang, Jun Song, Jian‐Ming Yang, Wei Wei   +4 more
wiley   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Use of hyaluronidase in the comparison between manual and automated hematology analysis with the ADVIA 120 to improve analysis of feline body cavity effusions [PDF]

, 2017
Classification of body cavity effusions is an important step in the investigation and diagnosis of disease in cats. Feline inflammatory effusions are often highly proteinaceous and viscous, which can cause clumping of white cells and subsequently ...
Haining, Hayley, Hulme-Moir, Lisa, Lee, Sei Ming, Weir, William, Williamson, Kenneth   +4 more
core   +1 more source