Results 101 to 110 of about 113,312 (290)

Indirubin and Retinoic Acid Show Binding Affinity to Monocyte Biomarker CSF3R in Parkinson's Disease

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Through single‐cell RNA‐sequencing and high‐dimensional weighted gene co‐expression network analysis, two monocyte‐related biomarkers (CSF3R, IFITM3) were identified in the peripheral blood of Parkinson's disease. Molecular docking revealed two targeted drugs (Indirubin and Retinoic acid).
Zhiwei Bao, Shao Zhi, Mao Jie
wiley   +1 more source

Effect of the Strawberry Genotype, Cultivation and Processing on the Fra a 1 Allergen Content [PDF]

open access: yes, 2018
Birch pollen allergic patients show cross-reactivity to vegetables and fruits, including strawberries (Fragaria × ananassa). The objective of this study was to quantify the level of the Fra a 1 protein, a Bet v 1-homologous protein in strawberry fruits
Kock, V.   +4 more
core   +2 more sources

Age‐related local versus systemic early phase wound healing dynamics following free gingival graft harvest

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Free palatal gingival grafts (FGG) are commonly harvested during mucogingival procedures. The present study investigates age‐related local and systemic early secondary wound healing outcomes, following FGG harvest in a rat model. Methods A 4.2 mm diameter defect was created in the palate of 24 younger (2 m) and 24 older (6 m) Wistar
Maayan Atzmon‐Shavit   +3 more
wiley   +1 more source

Revealing genetic causality between blood-based biomarkers and major depression in east Asian ancestry

open access: yesFrontiers in Psychiatry
IntroductionMajor Depression (MD) is a common mental disorder. In East Asian ancestry, the association, causality, and shared genetic basis between blood-based biomarkers and MD remain unclear.MethodsWe investigated the relationships between blood-based ...
Xiaoxiao Mo   +8 more
doaj   +1 more source

Innate type 2 immunity in helminth infection is induced redundantly and acts autonomously following CD11c+ cell depletion [PDF]

open access: yes, 2012
Infection with gastrointestinal helminths generates a dominant type 2 response among both adaptive (Th2) and innate (macrophage, eosinophil, and innate lymphoid) immune cell types.
Garbi, Natalio   +5 more
core   +1 more source

Lower Plasma Antioxidant Defense and Heat Shock Proteins Mark Intra‐Amniotic Sludge Ultrasound Finding

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Objectives Intra‐amniotic sludge is an independent risk factor for preterm birth. It consists of a biophysical sonographic finding in the amniotic fluid, formed by dense echogenic particles near the cervical internal orifice, due to sterile or infectious inflammatory processes.
Clarissa Chavez Ortiz Roberto   +8 more
wiley   +1 more source

Histamine Released From Skin-Infiltrating Basophils but Not Mast Cells Is Crucial for Acquired Tick Resistance in Mice

open access: yesFrontiers in Immunology, 2018
Ticks are blood-feeding arthropods that can transmit pathogens to humans and animals, leading to serious infectious diseases such as Lyme disease. After single or multiple tick infestation, some animal species develop resistance to tick feeding, leading ...
Yuya Tabakawa   +14 more
doaj   +1 more source

気管支喘息および慢性気管支炎患者における抗ヒトIgEによる好塩基球からのヒスタミン遊離 [PDF]

open access: yes, 1988
Histamine release from basophils induced by anti-IgE was studied in 8 patients with chronic bronchitis and 50 patients with bronchial asthma by analyzing doseresponse curves.
Araki, Hiroyuki   +6 more
core   +1 more source

A Refractory Leg Skin Ulcer Associated With Multiple Myeloma Successfully Treated With Plasma Exchange, Lenalidomide, and Dexamethasone

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori   +5 more
wiley   +1 more source

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