Basophil Activation in Immediate Drug Hypersensitivity Reactions and Basophil Activation Test (BAT)
In the basophil activation test (BAT), the expression of the degranulation marker lysosomal-associated membrane glycoprotein-3, also termed as CD63, or upregulation of CD203c is determined.
Öner Özdemir
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BASOPHIL ACTIVATION TEST (BAT) IN »IN VITRO« DIAGNOSIS OFHYMENOPTERA VENOM HYPERSENSITIVITY
BACKGROUND The basophil activation test relies on flow cytometric quantitation of the expression of themarkers on the surface of basophils, after stimulation with the amount of allergen thatcross-link IgE antibodies bound on their surface.
Andreja Peternelj +5 more
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Basophil Activation Test (BAT) for Diagnosing LTP Food Allergy: Where Do We Stand Now? A Systematic Review. [PDF]
LTP allergy and its accurate diagnosis remain a challenge in modern allergology. Patients sensitized to lipid transfer proteins (LTPs) present a wide range of symptoms, from mild manifestations—such as oral allergy syndrome, urticaria, and angioedema—to severe systemic reactions, including anaphylaxis.
Kosztulska B +4 more
europepmc +3 more sources
Correction: Groffmann et al. Identification of a New and Effective Marker Combination for a Standardized and Automated Bin-Based Basophil Activation Test (BAT) Analysis. <i>Diagnostics</i> 2024, <i>14</i>, 1959. [PDF]
There was an error in the original publication [...]
Groffmann J +8 more
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Respiratory allergy takes a significant place among allergic diseases. Similar clinical manifestations occur in sensitized patients in response to various airborne allergens.
N. V. Bychkova +3 more
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The diagnostic usefulness of the basophil activation test (BAT) with annexin V in an allergy to Alternaria alternata [PDF]
The basophil activation test (BAT) is an effective diagnostic tool in mold allergy, which is still not sufficiently known.The aim of our study was to assess the degree of annexin V binding to the surface of the basophil cell membrane after stimulation with anti-immunoglobulin E (anti-IgE) and Alternaria alternata allergenic extract.Alternaria alternata
Emilia, Królewicz +5 more
openaire +3 more sources
IgE receptor responsiveness of basophils in chronic inducible urticaria
IntroductionChronic inducible urticaria (CIndU) is a subgroup of chronic urticaria induced by a specific stimulus. We evaluated basophil characteristics in patients with CIndU and compared with those in patients with chronic spontaneous urticaria (CSU ...
Mayuko Mizuno +5 more
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Background: Cross-reactivity between pollen and plant foods results in low specificity of food-IgE and skin prick testing, which may cause over-diagnosis.
Shan Deng, Jia Yin
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Clinical utility of the basophil activation test in the diagnosis of sweat allergy
Background: Many patients with atopic dermatitis and cholinergic urticaria display an immediate-type allergy to autologous sweat. Although the histamine release test (HRT) using semi-purified sweat antigen (QR) was available for the detection of ...
Yoshiko Oda +8 more
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Basophil Activation Test With Aspergillus Molecules: The Case for ABPA
BackgroundAllergic bronchopulmonary aspergillosis (ABPA) is an underestimated allergic disease due to Aspergillus fumigatus (AF). The main diagnostic criteria for ABPA rely on the evaluation of immunoglobulin (Ig) E and IgG responses to AF extracts ...
Moïse Michel +15 more
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