Results 61 to 70 of about 1,964 (169)

CH50 as a Clinically Useful Biomarker of Disease Activity and Antihistamine Resistance in Chronic Spontaneous Urticaria: An Observational Ambispective Single‐Center Study

International Journal of Dermatology, Volume 65, Issue 10, Page 2066-2073, October 2026.
Personalized CSU care guided by CH50. ABSTRACT Background Chronic spontaneous urticaria (CSU) is frequently refractory to guideline‐based therapy, highlighting the need for predictive biomarkers. Dysregulation of the complement system has been implicated in CSU severity, but global complement activity has not been systematically evaluated.
Nidia Planella‐Fontanillas, Emilio Berna‐Rico, David Pesqué, Evelyn Andrades, Silvia Sánchez, Paloma Torres‐Bosó, Ramon Gimeno, Fernando Gallardo, Ramon M. Pujol, Ana M. Giménez‐Arnau   +9 more
wiley   +1 more source

Basophil activation test to BNT162b2 lacks specificity for predicting allergic reactions to the mRNA vaccine

Journal of Allergy and Clinical Immunology: Global
Background: Allergic reactions to the coronavirus 2019 disease (COVID-19) mRNA vaccine (BNT162b2) were originally reported at higher rates than expected, contributing to vaccine hesitancy and, in some cases, unnecessary vaccine avoidance.
Sydney Ann Kee, PhD, Ana Olivera, PhD, Lindsay Chatman, MSc, Muhammad B. Khalid, MD, Min Jenny Li, PhD, Eric Chu, MA, Ellen Zektser, BSN, MPH, Karen Laky, PhD, Pamela A. Frischmeyer-Guerrerio, MD, PhD   +8 more
doaj   +1 more source

Basophil Activation Test Provides Additional Diagnostic Value Beyond Ara h 2–Specific IgE Testing in Peanut Allergic Adults

Clinical &Experimental Allergy, EarlyView.
J. S. H. Schaapherder, K. C. M. Verhoeckx, E. F. Knol, D. Hamann, B. A. Wevers, A. C. Knulst, J. J. W. Kuiper, T. T. M. Le   +7 more
wiley   +1 more source

New Approaches for Basophil Activation Tests Employing Dendrimeric Antigen–Silica Nanoparticle Composites

Pharmaceutics
In vitro cell activation through specific IgE bound to high-affinity receptors on the basophil surface is a widely used strategy for the evaluation of IgE-mediated immediate hypersensitivity reactions to betalactams.
Silvia Calvo-Serrano, Esther Matamoros, Jose Antonio Céspedes, Rubén Fernández-Santamaría, Violeta Gil-Ocaña, Ezequiel Perez-Inestrosa, Cecilia Frecha, Maria I. Montañez, Yolanda Vida, Cristobalina Mayorga, Maria J. Torres   +10 more
doaj   +1 more source

The utility of the basophil activation test in the diagnosis of immediate amoxicillin or amoxicillin-clavulanate hypersensitivity in children and adults

Italian Journal of Pediatrics, 2017
Background The basophil activation test (BAT), has been proposed as a possible assay for the diagnosis of immediate-type allergy to beta-lactams (BLs).
Simona Barni, Francesca Mori, Claudia Valleriani, Giusi Mangone, Sergio Testi, Francesca Saretta, Lucrezia Sarti, Neri Pucci, Maurizio de Martino, Chiara Azzari, Elio Novembre   +10 more
doaj   +1 more source

Basophil Activation Test Predicts Cetuximab Anaphylaxis Severity in Alpha-Gal IgE-Positive Patients

Diagnostics
Upon first exposure to cetuximab, hypersensitivity reactions can occur. We aimed to assess the utility of the basophil activation test (BAT) to alpha-gal and cetuximab for predicting severe reactions.
Peter Kopač, Ana Koren, Urška Bidovec-Stojkovič, Mitja Košnik, Luka Dejanović, Tanja Mesti, Primož Strojan, Peter Korošec, Janja Ocvirk   +8 more
doaj   +1 more source

A Case of Immediate Hypersensitivity Reaction to Maltitol

Case Reports in Medicine, 2017
Background. Maltitol is a sugar alcohol that is frequently used as a noncaloric sweetener, although it is also used as an excipient, a plasticizer in gelatin capsules, and an emollient.
Ana Rodríguez Trabado, Carmen Cámara Hijón, José Antonio García-Trujillo, Irene Magriz Trascón, Luis Miguel Fernández Pereira   +4 more
doaj   +1 more source

[A clinical case of occupational allergy to piperacilline. A novel diagnostic method: basophil activation test (BAT)].

La Medicina del lavoro, 2014
Piperacillin, unlike other antibiotics, rarely causes immediate allergic reactions. Only two cases related to occupational exposure are reported in the literature.Adoption of new methods for diagnosis of occupational allergy to drugs.An atopic nurse, aged 30 years, was referred to our hospital for an allergic work-related reaction to piperacillin.
P, Marraccini, G, Digiesi, Patrizia, Pignatti, L, Bordini, M, Previdi   +4 more
openaire   +1 more source

Integrated Diagnostic Approach Using Basophil Activation Test and IgE Assays for Shrimp and Prawn Allergy

Medicina
Background and Objectives: Shellfish allergies are common in Vietnam. The basophil activation test (BAT) is a powerful tool in the diagnosis of food allergies.
Nhu N. Q. Nguyen, Thao H. Nguyen, Minh K. Le, Tram B. Duong, Duy L. Pham, Tai T. Tran, Tu H. K. Trinh   +6 more
doaj   +1 more source

Consideration of the EXiLE test for predicting anaphylaxis after diclofenac etalhyaluronate administration

Journal of Immunotoxicology
Diclofenac etalhyaluronate, an active pharmaceutical ingredient in JOYCLU® (JCL), serves as a joint function improvement agent in knee and hip osteoarthritis patients.
Haruyo Akiyama, Chisato Kurisaka, Dai Muramatsu, Shuhei Takada, Kei Toyama, Keiji Yoshioka, Ryosuke Nakamura   +6 more
doaj   +1 more source