Results 121 to 130 of about 56,684 (297)
The Evolution of Sesame Seed Allergy Over Time
Allergy, EarlyView.This study analyzes the natural history of sesame over time and the changes in biomarkers between sesame allergic and sesame sensitised but tolerant children. The period prevalence of sesame allergy increased from 0.5% between 12 and 36 m to 1.5% between 7 and 12 y children in the EAT‐On study with 10 children developing new sesame allergy. Sesame‐sIgE
Ru‐Xin Foong +14 more
wiley +1 more source
Navigating Oral Food Challenges in Clinical Trials to Keep the Science Moving Forward
Allergy, EarlyView.ABSTRACT The oral food challenge (OFC) has long been the reference standard for food allergy diagnosis, as well as to confirm natural development of oral tolerance. The utilization of OFCs has significantly broadened from its role in defining disease to defining participant eligibility, individual allergen reactivity thresholds and treatment outcomes ...
Edwin H. Kim +10 more
wiley +1 more source
Optimising the Diagnosis of Sesame Seed Allergy With the Basophil Activation Test
Allergy, EarlyView.The basophil activation test (using the activation marker CD203c) was the only test able to both exclude and confirm sesame seed allergy with precision. A negative skin prick test to sesame extract or tahini and undetectable IgE to Ses i 1 could not rule out sesame seed allergy.
Ru‐Xin Foong +16 more
wiley +1 more source
Allergy, EarlyView.High‐dose birch‐extract nasal challenge induced synchronous peaks at 4 weeks in serum specific IgE (sIgE) and basophil sensitivity. Mast cell sensitivity via tSPT and sIgG1 and sIgG4 responses peaked later, at 6–8 weeks. Preseasonal allergen exposure attenuated seasonal sIgE increase and prevented further rise in tSPT sensitivity.
N. J. Campion +18 more
wiley +1 more source
Basophils in skin inflammation
Japanese Journal of Clinical Immunology, 2011 Basophils represent less than 1% of peripheral blood leukocytes. Under physiological conditions, basophils principally circulate in peripheral blood, while mast cells reside in peripheral tissues. Like mast cells, they express the high-affinity IgE receptor on their cell surface and release chemical mediators.
openaire +3 more sources
Analysis of basophils activation status.
, 2016 (a) To identify basophils, we used the following gating sequence (shown in the figure by the red arrows): FSC-A/SSC-A (total white blood cells)→ FSС-A/FSC-H (singlets)→ CD41a/live/dead (CD41a—live)→ Dump [CD3, CD66b, HLA-DR]/CD123 (Dump—, CD123++)→ use ...
Gleb A. Kolyagin (2577880) +13 more
core +1 more source
Allergy, EarlyView.HDM‐pSLIT induced IgG, IgG1, and IgG4 specific to major HDM allergens in sensitized non‐allergic preschool children without increasing HDM‐sIgE. It blunted the development of new sensitizations and reduced HDM reactivity in skin and basophils. HDM‐pSLIT treated children displayed a blocking effect on HDM‐induced basophil activation.
Varsha Dwivedi +12 more
wiley +1 more source
, 2013 Background: Receptor Activator of Nuclear Factor kappaB Ligand (RANKL), a member of the TNF superfamily, contributes to the imbalance of bone resorption and immunoregulation in rheumatoid arthritis.
Fux, Michaela +3 more
core
Alcian blue staing of in vitro differentiated basophils and normal blood basophils.
, 2013 Panel A shows Alcian blue stained cells from day 9 of in vitro differentiated basophils originating from umbilical cord blood cultures stimulated with a continuous presence of 10 ng/ml IL-3.
Sofia E. Magnusson (300803) +5 more
core +1 more source
Polymeric α‐Hairpinin Allergens Induce a Functional Response via a Single Antibody
Allergy, EarlyView.
Gage O. Leighton +16 more
wiley +1 more source