Results 61 to 70 of about 221,159 (194)

The porin VDAC2 is the mitochondrial platform for Bax retrotranslocation

Scientific Reports, 2016
The pro-apoptotic Bcl-2 protein Bax can permeabilize the outer mitochondrial membrane and therefore commit human cells to apoptosis. Bax is regulated by constant translocation to the mitochondria and retrotranslocation back into the cytosol.
J. Lauterwasser, F. Todt, Ralf M. Zerbes, T. Nguyen, W. Craigen, M. Lazarou, Martin van der Laan, F. Edlich   +7 more
semanticscholar   +1 more source

Gyejibongnyeong-Hwan (Gui Zhi Fu Ling Wan) Ameliorates Human Uterine Myomas via Apoptosis

Frontiers in Pharmacology, 2019
Uterine leiomyomas are the most common benign neoplasms in women of reproductive age. However, non-surgical treatments for uterine myomas have not been fully evaluated.
So Min Lee, Eun Som Choi, Eun Som Choi, Eunyoung Ha, Kon Young Ji, So Jin Shin, Jeeyoun Jung   +6 more
doaj   +1 more source

ATP promotes cell survival via regulation of cytosolic [Ca2+] and Bcl-2/Bax ratio in lung cancer cells.

American Journal of Physiology - Cell Physiology, 2016
Adenosine triphosphate (ATP) is a ubiquitous extracellular messenger elevated in the tumor microenvironment. ATP regulates cell functions by acting on purinergic receptors (P2X and P2Y) and activating a series of intracellular signaling pathways.
Shanshan Song, Krista N. Jacobson, K. McDermott, S. Reddy, A. Cress, Haiyang Tang, S. Dudek, S. Black, Joe G. N. Garcia, A. Makino, J. Yuan   +10 more
semanticscholar   +1 more source

HSPB1 alleviates acute-on-chronic liver failure via the P53/Bax pathway

Open Life Sciences
The mortality rate of acute-on-chronic liver failure (ACLF) remains significantly elevated; hence, this study aimed to investigate the impact of heat shock protein family B (small) member 1 (HSPB1) on ACLF in vivo and in vitro and the underlying ...
Zhang Zhixiang, Guo Jinwei, Zhu Jincan
doaj   +1 more source

Freiheit und Notwendigkeit: Aus einem verlorenen Brief von Friedrich Engels an Ernest Belfort Bax vom Jahre 1886 [PDF]

, 1973
Hans-Josef Steinberg
openalex   +1 more source

Effect of Lutein on Proliferation and Apoptosis of Human Prostate Cancer PC3 Cell Line and Related Mechanism

Zhongliu Fangzhi Yanjiu, 2018
Objective To investigate the mechanism of lutein on the proliferation and apoptosis of human prostate cancer PC3 cells, and to provide a new theoretical basis for the treatment and prevention of prostate cancer.
WANG Liping, FU Lei, YE Shuke, LIU Weihua, WANG Yale, WANG Mingchen   +5 more
doaj   +1 more source

Examination of the apelin signaling pathway in acetaminophen-induced hepatotoxicity in rats

Türk Biyokimya Dergisi
The present study identifies the level changes of markers (Apelin, Elabela, Meteorin, ALT, AST, GGT) in the liver after acute intake of high-dose paracetamol and their role in determining liver damage.
Dolanbay Turgut, Makav Mustafa, Gul Huseyin Fatih, Karakurt Emin, Bektasoglu Fikret   +4 more
doaj   +1 more source

Growth factors prevent changes in Bcl-2 and Bax expression and neuronal apoptosis induced by nitric oxide [PDF]

, 1998
Michio Tamatani, Satoshi Ogawa, Gabriel Núñez, Masaya Tohyama   +3 more
openalex   +1 more source

Bax Homodimerization Is Not Required for Bax to Accelerate Chemotherapy-induced Cell Death [PDF]

, 1996
Philip L. Simonian, DidierA. M. Grillot, David W. Andrews, Brian Leber, Gabriel Núñez   +4 more
openalex   +1 more source

Bax Can Antagonize Bcl-XL during Etoposide and Cisplatin-induced Cell Death Independently of Its Heterodimerization with Bcl-XL [PDF]

, 1996
Philip L. Simonian, Didier Grillot, Ramón Merino, Gabriel Nu ez   +3 more
openalex   +1 more source