Results 61 to 70 of about 219,884 (241)
Evaluating the effects of hypoxia and taper on expression of Pulmonary Bax and Bcl2 apoptotic proteins [PDF]
Journal of Advanced Biomedical Sciences, 2018 Background & Objective: Due to The limitation of research literature, related to the effect of exercise training with different intensity, Along with Hypoxia Stress on Pulmonary Apoptosis, The purpose of this study was to investigate the effects of ...
Mehdi Yadegari +5 more
doaj
The great migration of Bax and Bak [PDF]
Molecular & Cellular Oncology, 2015 The Bcl-2 proteins Bcl-2-associated X protein (Bax) and Bcl-2 antagonist killer 1 (Bak) can commit cells to apoptosis. Retrotranslocation of Bax from the mitochondria into the cytosol is essential for cell survival. Recently, we reported that Bak is also present in the cytosol of healthy cells and that Bax and Bak are regulated by the same ...
openaire +3 more sources
Small Molecule Allosteric Inhibitors of BAX
Nature Chemical Biology, 2018 BAX is a critical effector of the mitochondrial cell death pathway in response to a diverse range of stimuli in physiological and disease contexts. Upon binding by BH3-only proteins, cytosolic BAX undergoes conformational activation and translocation ...
Thomas P. Garner +5 more
semanticscholar +1 more source
Frontiers in Pharmacology, 2023 Background: Herbs originating from the Aconitum L. (Ranunculaceae), such as Aconitum carmichaelii Debeaux. (Wutou), Aconitum pendulum Busch. (Tiebangchui), and Aconitum kusnezoffii Reichb. (Caowu), etc.
Gelin Xiang +7 more
doaj +1 more source
Journal of the Society for Musicology in Ireland, 2013 Scholars of Arnold Bax have long acknowledged the influence of the Irish Literary Revival on the composer’s compositional output up to about 1920, of Sibelius from the late 1920s onwards, and of the continuity of styles between these two periods. In this article I argue that this continuity relies on what Bax draws from early Yeats, which is less ...
openaire +2 more sources
Bax mitochondrial residency is more critical than Bax oligomerization for apoptosis [PDF]
, 2019 AbstractThe Bax protein plays an important effector role in apoptosis by forming pores in the mitochondrial outer membrane. While doing so, Bax forms higher-order oligomers in the membrane, but it remains unclear whether this oligomer formation is essential for pore formation. Using cell-free and cellular experimental systems, we investigated two Bax C-
Kuwana, Tomomi +6 more
openaire +2 more sources
Терапевтический архив, 2011 Aim. To determine unbalance in the system of programmed cell death in the cells CD34+ of the bone marrow (BM) and peripheral blood (PB) before and after cytostatic impact in acute leukemia (AL). Material and methods.
Elena Evgen'evna Khodunova +11 more
doaj
The Induction of Apoptosis by Resveratrol Through Regulatory Effect of miR-21 on the Gene Expression of Bcl2 and Bax in HCT-116 Cells [PDF]
Avicenna Journal of Medical Biochemistry, 2019 Background: Resveratrol (RezV) which is found in several plants including grapes and types of berries has a vital role in inducing apoptosis and suppressing cell proliferation.
Nooshin Shabab +2 more
doaj +1 more source
The Bax pore in liposomes, Biophysics [PDF]
Cell Death & Differentiation, 2006 The protein BAX of the Bcl-2-family is felt to be one of the two Bcl-2-family proteins that directly participate in the mitochondrial cytochrome c-translocating pore. We have studied the kinetics, stoichiometry and size of the pore formed by BAX in planar lipid bilayers and synthetic liposomes.
Mitsuyoshi Saito, Paul H. Schlesinger
openaire +3 more sources
bioRxiv, 2018 During apoptosis, Bcl-2 proteins such as Bax and Bak mediate the release of pro-apoptotic proteins from the mitochondria by clustering on the outer mitochondrial membrane and thereby permeabilizing it.
Nicholas R. Ader +6 more
semanticscholar +1 more source