Results 141 to 150 of about 153,854 (301)

Blood-brain barrier disruption: a culprit of cognitive decline?

open access: yesFluids and Barriers of the CNS
Cognitive decline covers a broad spectrum of disorders, not only resulting from brain diseases but also from systemic diseases, which seriously influence the quality of life and life expectancy of patients. As a highly selective anatomical and functional
Ji Che   +3 more
doaj   +1 more source

Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy

open access: yesAdvanced Science, EarlyView.
A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan   +9 more
wiley   +1 more source

Deformations of $\Bbb Q$-Calabi-Yau 3-Folds and $\Bbb Q$-Fano 3-Folds of Fano Index 1

open access: yes, 1999
In this article, we prove that any $\Bbb Q$-Calabi-Yau 3-fold with only ordinary terminal singularities and any $\Bbb Q$-Fano 3-fold of Fano index 1 with only terminal singularities have $\Bbb Q ...
Minagawa Tatsuhiro
core  

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

open access: yesAdvanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi   +7 more
wiley   +1 more source

Economic Score – BBB centre d’art

open access: yes, 2019
Partition, publicationLa pièce Economic score consiste en la transposition d’une économie culturelle en partition. La version « BBB centre d’art » comprend 3 tables à utiliser conjointement dans la préparation de l’interprétation.
Saladin, Matthieu
core  

Sonoselective Transfection of Glioma Endothelium

open access: yesAdvanced Science, EarlyView.
Delivering non‐viral, gene‐bearing nanoparticles with thiol‐decorated surfaces to gliomas with focused ultrasound yields transfection tropism for endothelial cells. From this platform, “sonoselective” transfection of glioma endothelium is achieved via incorporation of an endothelial cell‐specific promoter.
Anna C. Debski   +8 more
wiley   +1 more source

A fake smooth $\Bbb{CP}^2\#\Bbb{RP}^4$ [PDF]

open access: yesMathematical Research Letters, 1997
Daniel Ruberman, Ronald J. Stern
openaire   +1 more source

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

open access: yesAdvanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu   +7 more
wiley   +1 more source

Tame Galois realizations of $ GL_2(\Bbb F_l)$ over $\Bbb Q$

open access: yes, 2009
This paper concerns the tame inverse Galois problem. For each prime number l, we construct infinitely many semistable elliptic curves over Q with good supersingular reduction at l. The Galois action on the l-torsion points of these elliptic curves provides tame Galois realizations of GL_2(F_l) over Q.
ARIAS DE REYNA DOMINGUEZ, Sara   +1 more
openaire   +1 more source

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