Results 201 to 210 of about 116,953 (266)

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Overcoming the blood-brain barrier in Alzheimer's disease: translational perspectives on advanced drug delivery platforms. [PDF]

Front Neurosci
Roamcharern N, Yubolphan R.
europepmc   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

Nitric Oxide-S-Nitrosylation and Its Role in Neuroinflammation Associated with Neuropsychiatric Conditions. [PDF]

Int J Mol Sci
Sánchez F, Koning T.
europepmc   +1 more source

Adult‐onset CD8‐predominant hemispheric inflammatory epilepsy: Expanding the spectrum of post‐infectious and Rasmussen‐like encephalitis

Epileptic Disorders, EarlyView.
Ramya Raghupathi
wiley   +1 more source

Plant‐Derived Extracts Disrupt Biofilm Formation and Quorum Sensing in Yersinia enterocolitica: Insights From GC‐MS and Molecular Docking

Food Chemistry International, EarlyView.
The graphical abstract represents how natural plant products that preferentially target the specific receptors of quorum sensing could be developed to combat biofilms linked to Yersinia enterocolitica using the potent abilities of protein–ligand complexes with high docking scores.
Rajendran Thomas, Songeeta Singha, Devarshi Bharadwaj, Abinash Kumar, Dolly Sharma, Sadhana Ojha, Hirakjyoti Das, Vivek Kumar Gupta   +7 more
wiley   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Endothelial KLF4 depletion drives age-related neurovascular dysfunction and neuropsychiatric impairment. [PDF]

Proc Natl Acad Sci U S A
Dhar M, Vázquez-Rosa E, Chaubey K, Miller E, Corella SG, Chakraborty S, Tripathi SJ, Das T, Liao X, Alosman MA, Fang H, Koh Y, Sridharan PS, Franke K, Cintrón-Pérez CJ, Cintrón-Pérez AA, Tomco T, Indrakumar V, Rubin PJ, Pieper JG, Ashiku LA, Shin MK, Tang X, Padmanabhan R, Haragopal H, Flanagan ME, Jain R, Winters BD, Wilson BM, Paul BD, Jain MK, Pieper AA.   +31 more
europepmc   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Occludin-mediated barrier dysfunction and its role in cardiovascular and cerebrovascular pathogenesis. [PDF]

Front Cardiovasc Med
Xu W, Xu T, Long H, Jiang Q, Liao W.
europepmc   +1 more source