Results 71 to 80 of about 153,854 (301)

СURRENT CONCEPTS OF THE ROLE OF ALTERED BLOOD-BRAIN BARRIER RESISTANCE IN THE PATHOGENESIS OF CNS DISORDERS. PART II: FUNCTIONS AND MECHANISMS OF THE BLOOD-BRAIN BARRIER DAMAGE

open access: yesЭпилепсия и пароксизмальные состояния, 2016
: altered permeability of the blood-brain  barrier (BBB) plays a key role in the pathogenesis of epilepsy as well as vascular, demyelinating, neurodegenerative central neural system (CNS) diseases, head injury, hypoxic-ischemic CNS damage in obstetric ...
D. V. Blinov
doaj  

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

PATIENTS WITH NEUROLOGICAL DISEASES: RATIONALE FOR PHARMACOECONOMIC EVALUATION OF COST OPTIMIZATION FOR MANAGEMENT WITH NEURON-SPECIFIC PROTEINS ASSESSMENT AS MARKERS OF INCREASED BLOOD-BRAIN-BARRIER PERMEABILITY

open access: yesФармакоэкономика, 2015
becoming increasingly widespread evaluation of the blood-brain barrier (BBB) resistance to predict severity and outcome of epilepsy, stroke, traumatic brain injury (TBI) and other neurological disorders by assessment of neuron-specific proteins (NSP ...
D. V. Blinov
doaj  

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

open access: yesAdvanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian   +7 more
wiley   +1 more source

Innovations in Breaking Barriers: Liposomes as Near-Perfect Drug Carriers in Ischemic Stroke Therapy

open access: yesInternational Journal of Nanomedicine
Qiankun Zhang,* Songze Huang,* Xiaowen Liu, Wei Wang, Zhihan Zhu, Lukui Chen Department of Neurosurgery, Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine, Southern Medical University, Guangzhou, Guangdong ...
Zhang Q   +5 more
doaj  

THE GENERALITY OF NEUROBIOLOGICAL PROCESSES IN THE CNS DISORDERS

open access: yesЭпилепсия и пароксизмальные состояния, 2016
Generality of neurobiological processes in the most common CNS disorders could be verified. Thus, the acute pathology of the nervous system is accompanied by increased permeability ("breakthrough") of blood-brain barrier (BBB), which is trigger for ...
D. V. Blinov
doaj  

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

open access: yesAdvanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou   +4 more
wiley   +1 more source

EVALUATION OF BRAIN-BLOOD BARRIER PERMEABILITY FOR NEURON-SPECIFIC ENOLASE DURING PERINATAL HYPOXIC-ISCHEMIC LESION OF THE CNS

open access: yesАкушерство, гинекология и репродукция, 2016
There is a non-diminishing interest in the assessment of the blood-brain barrier (BBB) resistance and prediction of the severity and outcomes of the perinatal hypoxic-ischemic lesion of the CNS using the analysis of concentration of neuron-specific ...
D. V. Blinov
doaj  

Latina BBB-2 [PDF]

open access: yes, 1994
Liburu aipatuaren izenburua: Latina BBB-2 Liburuaren egilea(k): Ana Lazkoz ...
Bilbao Telletxea, Gidor
core  

BBB opening in V3.

open access: yes, 2013
A 3D Spoiled Gradient-Echo (SPGR) T1-weighted sequence was applied after intravenous (IV) injection of gadodiamide 1 h after sonication. Gadodiamide presence in the brain parenchyma is induced by BBB opening.
Yao-Sheng Tung (347676)   +4 more
core   +1 more source

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