Results 11 to 20 of about 43,134 (252)
Liver X Receptor as a Possible Drug Target for Blood-Brain Barrier Integrity [PDF]
Purpose: blood-brain barrier (BBB) is made of specialized cells that are responsible for theselective passage of substances directed to the brain. The integrated BBB is essential for precisecontrolling of the different substances passage as well as ...
Mahsa Eskandari, Ali Awsat Mellati
doaj +1 more source
In this issue of Developmental Cell, Anbalagan et al. demonstrate that pituicytes, a subtype of astroglia, drive endothelial cell permeability in the zebrafish embryo neurohypophysis. This occurs via secretion of Vegfa/Tgfβ3 permeability factors that promote formation of fenestrae and the repression of anti-inflammatory retinoic acid signaling that ...
Thomas, Jean-Léon, Eichmann, Anne
openaire +3 more sources
Effect of Endurance Exercise and Methamphetamine Administration on the Expression of Blood-Brain Barrier Related Factors and BDNF in Hippocampus of Male Sprague-Dawley Rat [PDF]
PURPOSE This study aimed to investigate the effect of short-term endurance exercise and methamphetamine administration on bloodbrain barrier (BBB)-related marker and brain-derived neurotrophic factor (BDNF) in the hippocampus of male Sprague-Dawley (SD ...
Su-Ryun Jung
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Triolein emulsion enhances temozolomide brain delivery: an experimental study in rats
Purpose To evaluate the enhancement of temozolomide (TMZ) delivery in the rat brain using a triolein emulsion. Materials and Methods Rats were divided into the five groups as following: group 1 (negative control), group 2 (treated with triolein emulsion ...
Won-Bae Seung +10 more
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On bornological semi-abelian algebras [PDF]
If $\Bbb T$ is a semi-abelian algebraic theory, we prove that the category ${\rm Born}^{\Bbb T}$ of bornological $\Bbb T$-algebras is homological with semi-direct products.
Francis Borceux, Maria Manuel Clementino
doaj +1 more source
Managing blood cholesterol levels is important for the treatment and prevention of diabetes, cardiovascular disease, and obesity. An easy-to-use, portable cholesterol blood test could accelerate more frequent testing by patients and at-risk populations ...
Kyongsik Yun +3 more
doaj +1 more source
Trans-BBB peptides for targeting brain metastasis
Cancer is a heterogeneous and still not well-understood disease, being one of the most significant health problems worldwide. Among women, the most common cancer type is breast cancer. It accounts for 1 in 4 cancer cases and 1 in 6 cancer deaths.
Cavaco, Marco
core +1 more source
The Blood–Brain Barrier (BBB) Score
The blood–brain barrier (BBB) protects the brain from the toxic side effects of drugs and exogenous molecules. However, it is crucial that medications developed for neurological disorders cross into the brain in therapeutic concentrations.
Hyeok Jun Lee (7543277) +3 more
core +4 more sources
Deciphering the role of MYC Gene Variants in Childhood Cerebral Adrenoleukodystrophy (ccALD) using Integrative Transcriptomic and Variant Analysis [PDF]
Objective: Childhood cerebral adrenoleukodystrophy (ccALD) is a severe neurodegenerative disorder characterized by rapid demyelination and disruption of the blood-brain barrier (BBB).
Jain Chakresh Kumar +3 more
doaj +1 more source
Discrete parabolic groups in ${\rm PSL}(3, \Bbb{C})$ [PDF]
We study and classify the purely parabolic discrete subgroups of $PSL(3,\Bbb{C})$. This includes all discrete subgroups of the Heisenberg group ${\rm Heis}(3,\Bbb{C})$.
Cano, Angel +3 more
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