Results 61 to 70 of about 159,800 (296)

In vivo approaches to assessing the blood-brain barrier

open access: yes, 2014
Methods for in vivo assessment of blood-brain barrier (BBB) transport are presented, with their advantages and disadvantages. The methods described are brain uptake index, the i.v.
Hammarlund-Udenaes, Margareta,
core   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou   +6 more
wiley   +1 more source

Einige fühlen den Regen, andere werden nass (UA): von BBB Johannes Deimling, Theaterakademie, Kleine Bühne : 12+

open access: yes
Was sehen, hören, spüren wir von der Welt? Wie entschlüsseln wir diese Eindrücke? Warum entreißen wir ihnen ihr Geheimnis? In der Arbeit an der Inszenierung „Einige fühlen den Regen, andere werden nass“ haben Jugendliche ihr Verständnis von ...

core   +2 more sources

Mechanisms of Astrocyte Action in the Blood Brain Barrier: From Structural Support to Dynamic Regulation

open access: yesJournal of Integrative Neuroscience
The blood-brain barrier (BBB) consists of endothelial cells enmeshed by brain microvessels, surrounding basement membrane, pericytes and astrocyte pedicles.
Di Feng   +3 more
doaj   +1 more source

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

open access: yesAdvanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou   +4 more
wiley   +1 more source

“Build back better” approach to disaster recovery: Research trends since 2006

open access: yesProgress in Disaster Science, 2019
The “build back better” (BBB) approach to disaster recovery was first introduced in 2006 by the United Nations Secretary-General's Special Envoy for Tsunami Recovery, former US President William Clinton.
Glenn Fernandez, Iftekhar Ahmed
doaj   +1 more source

Binary sequences which contain no $BBb$ [PDF]

open access: yesTransactions of the American Mathematical Society, 1980
A (one-sided) sequence or (two-sided) bisequence is irreducible provided it contains no block of the form BBb, where b is the initial symbol of the block B. Gottschalk and Hedlund [Proc. Amer. Math. Soc. 15 (1964), 70-74] proved that the set of irreducible binary bisequences is the Morse minimal set M. Let M+ denote the one-sided Morse minimal set, i.e.
openaire   +2 more sources

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

open access: yesAdvanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang   +5 more
wiley   +1 more source

BBB pathophysiology–independent delivery of siRNA in traumatic brain injury

open access: yes, 2021
Copyright © 2021 The Authors, some rights reserved. Small interfering RNA (siRNA)–based therapeutics can mitigate the long-term sequelae of traumatic brain injury (TBI) but suffer from poor permeability across the blood-brain barrier (BBB).
Zhang, Jingdong   +25 more
core   +1 more source

Cell‐Based Biohybrid Micro/Nanorobots for Biotherapy

open access: yesAdvanced Robotics Research, EarlyView.
This review systematically evaluates cell‐based biohybrid micro/nanorobots (CB‐BMRs), highlighting their cell selection criteria, fabrication strategies, and diverse actuation modes. Furthermore, it surveys the promising therapeutic applications of CB‐BMRs in targeted cancer, thrombosis, and inflammation treatments, while comprehensively discussing ...
Lin Wang   +11 more
wiley   +1 more source

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