Results 41 to 50 of about 153,854 (301)
OBJECTIVE METHODS FOR DETERMINE THE SEVERITY AND PROGNOSIS OF PERINATAL HYPOXIC-ISCHEMIC CNS
Perinatal hypoxic-ischemic damage of the CNS is a major cause of mortality and neonatal incapacitating. The severity and prognosis is not always possible to accurately determine by clinical and tools methods of examination.
D. V. Blinov
doaj
Blood–brain barrier (BBB) impairment is an early prevalent feature of multiple sclerosis (MS), and remains vital for MS progression. Microglial activation precedes BBB disruption and cellular infiltrates in the brain of MS patients.
Zhongwang Yu +12 more
doaj +1 more source
Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong +10 more
wiley +1 more source
Background Evidence exists pointing out how non-adherence to treatment remains a major hurdle to efficient tuberculosis control in developing countries.
Tadele Teshome Woimo +3 more
doaj +1 more source
Endothelial Cell Proteins as Biomarkers in Susac Syndrome
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin +11 more
wiley +1 more source
Was sehen, hören, spüren wir von der Welt? Wie entschlüsseln wir diese Eindrücke? Warum entreißen wir ihnen ihr Geheimnis? In der Arbeit an der Inszenierung „Einige fühlen den Regen, andere werden nass“ haben Jugendliche ihr Verständnis von ...
core +2 more sources
The integrity of the blood–brain barrier (BBB) is essential for normal central nervous system (CNS) functioning. Considering the significance of BBB in maintaining homeostasis and the neural environment, we aim to provide an overview of significant ...
Hema Kumari Alajangi +9 more
doaj +1 more source
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou +6 more
wiley +1 more source
On solvability of linear differential equations in ${\Bbb R}^{\Bbb N}$
We construct $x^0$ in ${\Bbb R}^{\Bbb N}$ and a row-finite matrix $T=\{T_{i,j}(t)\}_{i,j\in\N}$ of polynomials of one real variable $t$ such that the Cauchy problem $\dot x(t)=T_tx(t)$, $x(0)=x^0$ in the Fr\'echet space $\R^\N$ has no solutions.
Shkarin, Stanislav
core +2 more sources
Let $R$ be a complete discrete valuation ring of equal characteristic $p>0$. In this paper we investigate finite and flat morphisms $f:Y\to X$ between formal $R$-schemes which have the structure of an etale $\Bbb Z/p^n\Bbb Z$-torsor above the generic fiber of $X$, for $n=1,2$, with some extra geometric conditions on $X$ and $Y$.
openaire +2 more sources

