Results 151 to 160 of about 159,800 (296)

The Potential Therapeutic Effect of Nanomaterials on Central Nervous System Disorders. [PDF]

Int J Nanomedicine
Shao X, Li Z, Zhu J, Kou Q, Sun K, Xue Y.   +5 more
europepmc   +1 more source

Tame Galois realizations of $ GL_2(\Bbb F_l)$ over $\Bbb Q$

, 2009
This paper concerns the tame inverse Galois problem. For each prime number l, we construct infinitely many semistable elliptic curves over Q with good supersingular reduction at l. The Galois action on the l-torsion points of these elliptic curves provides tame Galois realizations of GL_2(F_l) over Q.
ARIAS DE REYNA DOMINGUEZ, Sara, Vila, Núria   +1 more
openaire   +1 more source

A Chiral Virus‐Like Nanoplatform That Broadly Mediates Antibiotic Delivery to the Brain for Bacterial Meningitis Therapy

Advanced Science, EarlyView.
Chiral virus‐mimicking mesoporous silica nanostructures (CVSNs) efficiently transport diverse antibiotics across the blood–brain barrier (BBB) into brain parenchyma and cerebrospinal fluid. By enhancing delivery to microglia and astrocytes, CVSNs improve antibiotic bioavailability and therapeutic efficacy against both Gram‐negative and Gram‐positive ...
Qianqian Xu, Xuting Zheng, Huinan Tong, Ying Liu, Xiaoxi Fan, Miao Xu, Ziyan Zhang, Li Zhang, Mingyan Liu, Ting Du, Heran Li, Guojun Liu   +11 more
wiley   +1 more source

Blood Brain Barriers (BBB): Its Role & How It Works

BBB is a multicellular semi-permeable membrane that prevents toxic and harmful substances from entering the Central Nervous System. The presence of BBB avoids the brain from damage by keeping a stable environment.
Habiya, Sana
core   +1 more source

miR-21a-5p targets DDX58 to suppress TLR2/NF-κB signaling and protect the blood-brain barrier after injury. [PDF]

Mol Biol Rep
Yang J, Tang N, Dai R, Fu H, Li S, Meng Q.   +5 more
europepmc   +1 more source

BBB building [PDF]

The Journal of Cell Biology, 2008
openaire   +1 more source

Engineered Chiral Probiotics Ameliorate MASH via Gut–Liver Axis

Advanced Science, EarlyView.
A chiral gold nanozyme was coated onto the gut commensal bacterium Faecalibacterium duncaniae (F. duncaniae) to create an engineered probiotic. In mouse models of MASH, this orally administered living therapeutic protected the bacterium against oxidative stress, enhanced its gut colonization, reversed steatosis, inflammation, and fibrosis, and improved
Jing Chen, Shen Zhang, Yuli Zhu, Da Zhou, Chunya Ji, Mingrui Zhu, Sirui Wang, Yuting Shen, Jifeng Yu, Heng Zhang, Yan Fang, Huixiong Xu, Haohao Yin   +12 more
wiley   +1 more source

An Update on Blood-Brain Barrier Penetrating Nanoparticles for the Treatment of Glioblastoma. [PDF]

Int J Nanomedicine
McGranaghan CT, VanKeulen-Miller R, Fenton OS, McErlean EM.   +3 more
europepmc   +1 more source

Cross‐Organ Multi‐Omics Profiling of Systemic Alterations in 5xFAD Mice and Changes Associated with Huanglian Jiedu Decoction Treatment

Advanced Science, EarlyView.
Cross‐organ multi‐omics reveals coordinated inflammatory and metabolic disturbances in 5xFAD mice. Huanglian Jiedu Decoction improves cognition and alleviates brain and liver abnormalities. Complementary hepatocyte–microglia conditioned‐medium experiments suggest PPAR‐γ involvement in treatment‐associated changes in microglial inflammation, providing ...
Wenya Gao, Jing Gao, Xiaohui Su, Xiangying Kong, Xiaolu Wei, Tunan Ding, Tiantian Guo, Shuangrong Gao, Yanyan Zhou, Junyi Zhou, Haiyu Zhao   +10 more
wiley   +1 more source

Therapeutic delivery systems need to focus on cellular precision to target neurodegeneration. [PDF]

PLoS Biol
Gupta L, Agilkaya S, Keller KS, Ercan-Herbst E.   +3 more
europepmc   +1 more source