Results 111 to 120 of about 43,134 (252)

Sonoselective Transfection of Glioma Endothelium

open access: yesAdvanced Science, EarlyView.
Delivering non‐viral, gene‐bearing nanoparticles with thiol‐decorated surfaces to gliomas with focused ultrasound yields transfection tropism for endothelial cells. From this platform, “sonoselective” transfection of glioma endothelium is achieved via incorporation of an endothelial cell‐specific promoter.
Anna C. Debski   +8 more
wiley   +1 more source

Minimal surfaces in ${\Bbb M}\sp 2\times\Bbb R$

open access: yesIllinois Journal of Mathematics, 2002
We study the geometry and topology of properly embedded minimal surfaces in $M\times\mathbb{R}$, where $M$ is a Riemannian surface. When $M$ is a round sphere, we give examples of all genus and we prove such minimal surfaces have exactly two ends or equal $M\times\{t\}$, for some real $t$.
openaire   +2 more sources

Mechanisms of T-cell migration across the BBB

open access: yes, 2011
Under physiological conditions, the highly specialized BBB strictly limits the entrance of immune cells into the CNS. By contrast, in the course of neuroinflammation such as that observed in multiple sclerosis, circulating T cells readily breach the BBB ...
Ruth Lyck, Roberta Martinelli
core   +1 more source

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

open access: yesAdvanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu   +7 more
wiley   +1 more source

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu   +12 more
wiley   +1 more source

Microstructural and phase evolution of BaTiO3–BaO–B2O3–Bi2O3 glass composites during pressureless and spark plasma sintering

open access: yesMaterials & Design
BaTiO3–BaO–B2O3–Bi2O3 (BBB) glass composites were investigated to clarify how BBB content and sintering route control low-temperature densification, pore evolution, glass-derived phase redistribution, and crystalline phase development.
Alfian Noviyanto   +5 more
doaj   +1 more source

$\Omega_{bbb}\Omega_{bbb}\Omega_{bbb}$ tribaryons

open access: yes
We study the possible existence of bound states of three $\Omega_{bbb}$ baryons. We consider only $S$ wave interactions and we start from recent lattice QCD results which give a strongly attractive potential between two $\Omega_{bbb}$ baryons in the $^1S_0$ channel. We analyze different scenarios.
Garcilazo, H., Valcarce, A.
openaire   +1 more source

Homomorphic images of $\Bbb R$-factorizable groups

open access: yes, 2006
summary:It is well known that every $\Bbb R$-factorizable group is $\omega $-narrow, but not vice versa. One of the main problems regarding $\Bbb R$-factorizable groups is whether this class of groups is closed under taking continuous homomorphic images ...
Tkachenko, M.
core  

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen   +7 more
wiley   +1 more source

Human BBB-on-a-Chip using iPSCs Derived HBMECs

open access: yes, 2019
Blood-Brain Barrier(BBB) is a diffusion barrier protecting our brain and central nervous system (CNS) by blocking the harmful substances crossing from blood to brain. Ironically, the BBB structure becomes a major obstacle for drug delivery to treat brain
Park, Tae-Eun   +4 more
core  

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