Results 141 to 150 of about 141,528 (311)
Hydrogel-based microfluidic model of the blood-brain barrier: progress and future perspectives
Fluids and Barriers of the CNSThe development of brain-targeted delivery systems is significantly hindered by the blood-brain barrier (BBB), which prevents drugs from effectively reaching therapeutic regions in the brain.
Fangyuan Guo +7 more
doaj +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Angewandte Chemie, EarlyView.In ein vollständig auf Proteinen basierendes Hydrogel wurden zwei orthogonale Photorezeptoren integriert, um die reversible Manipulation der Steifigkeit durch rotes/fernrotes Licht und den irreversiblen Gel‐Sol‐Übergang durch grünes Licht zu ermöglichen.
Saskia Frank, Seraphine V. Wegner
wiley +1 more source
OCA and towers in $\Cal P(\Bbb N)/fin$
, 1996 summary:We shall show that Open Coloring Axiom has different influence on the algebra $\Cal P(\Bbb N)/fin$ than on $\Bbb N^\Bbb N/fin$.
Farah, Ilijas
core
Angewandte Chemie International Edition, EarlyView.A fully protein‐based hydrogel integrated two orthogonal photoreceptors to enable reversible manipulation of stiffness with red/far‐red light and irreversible gel‐sol transitions with green light. Unexpectedly, high‐intensity red light results in attenuated stiffening and dark‐adaptation, arising from increased crosslinking dynamics in the ...
Saskia Frank, Seraphine V. Wegner
wiley +1 more source
Blood-brain barrier disruption: a culprit of cognitive decline?
Fluids and Barriers of the CNSCognitive decline covers a broad spectrum of disorders, not only resulting from brain diseases but also from systemic diseases, which seriously influence the quality of life and life expectancy of patients. As a highly selective anatomical and functional
Ji Che +3 more
doaj +1 more source
Journal of the American Oil Chemists' Society, EarlyView.ABSTRACT Plants are important sources of bioactive compounds that contribute to nutrition, health maintenance, and disease prevention. In this study, the chemical composition and antioxidant potential of essential oils obtained from Lavandula angustifolia “Sevtopolis” and Lavandula × intermedia cultivated in the Silivri region of Istanbul were ...
Bilge Bicak +4 more
wiley +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum +5 more
wiley +1 more source
Proceedings of the National Academy of Sciences, 2022 Pearson, Caroline A. +1 more
openaire +2 more sources