Results 51 to 60 of about 117,524 (267)

The prevalence and factors associated for anti-tuberculosis treatment non-adherence among pulmonary tuberculosis patients in public health care facilities in South Ethiopia: a cross-sectional study

open access: yesBMC Public Health, 2017
Background Evidence exists pointing out how non-adherence to treatment remains a major hurdle to efficient tuberculosis control in developing countries.
Tadele Teshome Woimo   +3 more
doaj   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin   +11 more
wiley   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

open access: yesAdvanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández   +14 more
wiley   +1 more source

On the degeneration of étale $\Bbb Z/p\Bbb Z$ and $\Bbb Z/p^2\Bbb Z$-torsors in equal characteristic $p>0$

open access: yesHiroshima Mathematical Journal, 2007
Let $R$ be a complete discrete valuation ring of equal characteristic $p>0$. In this paper we investigate finite and flat morphisms $f:Y\to X$ between formal $R$-schemes which have the structure of an etale $\Bbb Z/p^n\Bbb Z$-torsor above the generic fiber of $X$, for $n=1,2$, with some extra geometric conditions on $X$ and $Y$.
openaire   +2 more sources

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett   +7 more
wiley   +1 more source

Microglia Regulate Blood–Brain Barrier Integrity via MiR‐126a‐5p/MMP9 Axis during Inflammatory Demyelination

open access: yesAdvanced Science, 2022
Blood–brain barrier (BBB) impairment is an early prevalent feature of multiple sclerosis (MS), and remains vital for MS progression. Microglial activation precedes BBB disruption and cellular infiltrates in the brain of MS patients.
Zhongwang Yu   +12 more
doaj   +1 more source

Binary sequences which contain no $BBb$ [PDF]

open access: yesTransactions of the American Mathematical Society, 1980
A (one-sided) sequence or (two-sided) bisequence is irreducible provided it contains no block of the form BBb, where b is the initial symbol of the block B. Gottschalk and Hedlund [Proc. Amer. Math. Soc. 15 (1964), 70-74] proved that the set of irreducible binary bisequences is the Morse minimal set M. Let M+ denote the one-sided Morse minimal set, i.e.
openaire   +2 more sources

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave   +8 more
wiley   +1 more source

Brain Pericytes — Crucial Regulators of Neuroinflammation in Ischemic Stroke

open access: yesNeuropharmacology and Therapy
Inflammation is a key element in the pathophysiology of ischemic stroke. The current effective treatments for ischemic stroke are almost exclusively based on reperfusion of occluded vessels.
Ziyi Chen   +5 more
doaj   +1 more source

“Build back better” approach to disaster recovery: Research trends since 2006

open access: yesProgress in Disaster Science, 2019
The “build back better” (BBB) approach to disaster recovery was first introduced in 2006 by the United Nations Secretary-General's Special Envoy for Tsunami Recovery, former US President William Clinton.
Glenn Fernandez, Iftekhar Ahmed
doaj   +1 more source

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