Results 211 to 220 of about 154,979 (298)

T Cell‐Mediated Targeting of Interneurons in Mice Shapes Hippocampal Remodeling and Epilepsy

Annals of Neurology, EarlyView.
Objective Autoimmune encephalitis (AE) is associated with autoantibodies targeting distinct neuronal populations. In AE, antibodies against glutamate decarboxylase 65 (GAD65), expressed in GABAergic interneurons, are frequently detected. In GAD65‐AE, hippocampal biopsies often show infiltrates of CD8+ cytotoxic T cells (CTLs), suggesting a prominent T ...
Daniel S. Galvis‐Montes, Lukas Henning, Karen M. J. van Loo, Rainer Surges, Susanne Schoch, Albert J. Becker, Julika Pitsch   +6 more
wiley   +1 more source

Multiple Sclerosis and Viruses: « Liaisons Dangereuses ». [PDF]

Rev Med Virol
Plavina S, Malakovska D, Kalnina J, Trapina I, Leonova E, Habib M, Schifmann S, Paramonovs J, Sjakste N, Vassetzky Y, Drouet E, Paramonova N.   +11 more
europepmc   +1 more source

Functional Polymer‐Engineered Magnetic Nanoparticles as Dual‐Modal Theragnostic Probes for Early Alzheimer's Disease Detection and Therapy

Advanced NanoBiomed Research, EarlyView.
The nanoparticle consists of a 3 nm iron oxide core functionalized with an amphiphilic polymer coating containing Aβ‐targeting DSA moieties and biocompatible PEG chains. This design supports measurable transport in a BBB‐related model and specific interaction with Aβ species, while providing MRI contrast enhancement for diagnosis and therapeutic ...
Ao Shen, Liwen Zhang, Helen Forgham, Jiayuan Zhu, Xumin Huang, Changkui Fu, Ibrahim Javed, Thomas P. Davis, Ruirui Qiao   +8 more
wiley   +1 more source

Mitochondrial control of blood-brain barrier homeostasis in neuroinflammatory psychiatric disorders. [PDF]

Front Mol Neurosci
Pérez-López LM, Camacho-Morales A, Howland-Álvarez I, Pérez-Maya AA.   +3 more
europepmc   +1 more source

Microbial phenolic metabolites at the neurovascular interface: a precision-nutrition framework for brain aging. [PDF]

Front Nutr
Das SK, K M, Nerune SM, Parveen A, Karak P.   +4 more
europepmc   +1 more source

Biohybrid M13 phage backpacks for active blood-brain barrier traversal and precision central nervous system leukemia treatment. [PDF]

Biomark Res
Wu W, Zhang CL, Yang YL, Chen X, Zhang X, Dong X.   +5 more
europepmc   +1 more source

Therapeutic Potential of Berberine in Obesity-Associated Neuroinflammation Through Shared Molecular Pathways: TLR4/NF-κB/MAPK, ROS/NRF2 and NLRP3. [PDF]

Nutrients
Moyetón-Hernández MDR, Bandala C, Guadarrama-Castillo M, Medina-Santillán R, Lara-Padilla E.   +4 more
europepmc   +1 more source