Results 111 to 120 of about 166,673 (273)

Durvalumab: an investigational anti-PD-L1 monoclonal antibody for the treatment of urothelial carcinoma. [PDF]

open access: yes, 2018
Our expanding knowledge of immunotherapy for solid tumors has led to an explosion of clinical trials aimed at urothelial carcinoma. The primary strategy is centered on unleashing the immune system by releasing the inhibitory signals propagated by ...
Chamie, Karim   +5 more
core   +1 more source

What if Adam Smith Debated an AI Economist: A Thought Experiment on Markets, Ethics, and the Invisible Hand

open access: yesBusiness Ethics, the Environment &Responsibility, EarlyView.
ABSTRACT Can AI‐driven capitalism sustain the moral preconditions of market order? We stage a dialogue between Adam Smith and a steel‐manned “EconAI” to test four Moral‐Market‐Fitness criteria: trustworthiness, fairness, non‐domination, and contestability, across 11 dilemmas.
Alexandra‐Codruța Bîzoi   +1 more
wiley   +1 more source

A luminal non‐coding RNA‐based genomic classifier confirms favourable outcomes in patients with clinically organ‐confined bladder cancer treated with radical cystectomy

open access: yesBJU International, Volume 135, Issue 4, Page 648-656, April 2025.
Objective To further evaluate a genomic classifier (GC) in a cohort of patients undergoing radical cystectomy (RC), as long non‐coding RNA (lncRNA)‐based genomic profiling has suggested utility in identifying a distinct tumour subgroup corresponding to a favourable prognosis in patients with bladder cancer.
Joep J. de Jong   +14 more
wiley   +1 more source

Management of Bacille Calmette-Guérin Vaccine Adverse Event: Case Report

open access: yesBagcilar Medical Bulletin
Bacillus Calmette-Guérin (BCG) vaccine is used worldwide as an important preventive vaccine against tuberculosis. It is a safe vaccine with a low incidence of serious side effects. However, some adverse events may be observed.
Gizem Kara Elitok
doaj   +1 more source

QMR: A Quasi-Minimal Residual method for non-Hermitian linear systems [PDF]

open access: yes
The biconjugate gradient (BCG) method is the natural generalization of the classical conjugate gradient algorithm for Hermitian positive definite matrices to general non-Hermitian linear systems.
Freund, Roland W., Nachtigal, Noel M.
core   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Living on the edge – physiological tolerance to frost and drought explains range limits of 35 European tree species

open access: yesEcography, EarlyView.
Species distribution models are key to evaluate how climate change threatens European forests and tree species distributions. However, current models struggle to integrate ecophysiological processes. Mechanistic models are complex and have high parameter requirements.
Anne Baranger   +6 more
wiley   +1 more source

A minor high‐grade component in non‐invasive papillary urothelial carcinoma is not associated with a more indolent behaviour

open access: yesHistopathology, EarlyView.
Non‐invasive papillary urothelial carcinomas with minor high‐grade component are not associated with a more indolent behavior and should likely be regarded as high‐grade carcinomas. Aims The latest WHO edition proposed using a cut‐off of ≥5% high‐grade component (%HGc) as a criterion to label non‐invasive papillary urothelial carcinomas as high‐grade ...
Mina S. Farag   +5 more
wiley   +1 more source

Profitability of private brands of e‐commerce platforms offering competing national brands under agency selling

open access: yesInternational Transactions in Operational Research, EarlyView.
Abstract This paper investigates the impact of a private brand (PB) introduction by an e‐commerce platform. Contrary to previous research, the platform allows competing manufacturers to sell their national brands (NBs) directly to consumers for an agency fee. Our game‐theoretic analysis allows us to derive the following key insights.
Salma Karray, Simon P. Sigué
wiley   +1 more source

A clinical case of disseminated BCG infection with a fatal outcome

open access: yesЖурнал инфектологии
Complications after the introduction of the tuberculosis vaccine develop extremely rarely. They become accidentally vaccinated infants with undiagnosed severe immunodeficiency.
S. M. Kharit   +6 more
doaj   +1 more source

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