Results 41 to 50 of about 806,785 (277)

Correlation between universal BCG vaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study

medRxiv, 2020
COVID-19 has spread to most countries in the world. Puzzlingly, the impact of the disease is different in different countries. These differences are attributed to differences in cultural norms, mitigation efforts, and health infrastructure.
Aaron Miller, Mac Josh Reandelar, K. Fasciglione, Violeta Roumenova, Yan Li, Gonzalo H. Otazu   +5 more
semanticscholar   +1 more source

Effects of BCG vaccination on donor unrestricted T cells in two prospective cohort studies

EBioMedicine, 2022
Summary Background Non-protein antigen classes can be presented to T cells by near-monomorphic antigen-presenting molecules such as CD1, MR1, and butyrophilin 3A1.
A. Gela, Melissa Murphy, Miguel J. Rodo, K. Hadley, W. Hanekom, W. Boom, J. E. Johnson, D. Hoft, S. Joosten, T. Ottenhoff, Sara Suliman, D. Moody, D. Lewinsohn, M. Hatherill, C. Seshadri, E. Nemes, T. Scriba, Libby Briel, Hellen Veldtsman, N. Khomba, Bernadette Pienaar, Hadn Africa, Marcia Steyn   +22 more
semanticscholar   +1 more source

BCG vaccination strategies against tuberculosis: updates and perspectives

Human Vaccines & Immunotherapeutics, 2021
Bacillus Calmette-Guérin (BCG) is the only licensed vaccine against tuberculosis (TB). However, BCG has variable efficacy and cannot completely prevent TB infection and transmission.
Meng-Jin Qu, Xiang-Mei Zhou, Hao Li
semanticscholar   +1 more source

Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with BCG: a Retrospective Cohort Study

Cell Reports Medicine, 2020
Summary: Bacille Calmette-Guérin (BCG) induces long-term boosting of innate immunity, termed trained immunity, and decreases susceptibility to respiratory tract infections.
Simone J.C.F.M. Moorlag, Rosanne C. van Deuren, Cornelis H. van Werkhoven, Martin Jaeger, Priya Debisarun, Esther Taks, Vera P. Mourits, Valerie A.C.M. Koeken, L. Charlotte J. de Bree, Thijs ten Doesschate, Maartje C. Cleophas, Sanne Smeekens, Marije Oosting, Frank L. van de Veerdonk, Leo A.B. Joosten, Jaap ten Oever, Jos W.M. van der Meer, Nigel Curtis, Peter Aaby, Christine Stabell-Benn, Evangelos J. Giamarellos-Bourboulis, Marc Bonten, Reinout van Crevel, Mihai G. Netea   +23 more
doaj   +1 more source

Exploring spatial variation in BCG vaccination among children 0–35 months in Ethiopia: spatial analysis of Ethiopian Demographic and Health Survey 2016

BMJ Open, 2021
Objective Tuberculosis is a major public health problem and is the second leading cause of death worldwide. BCG vaccination is a life-saving and important part of standard tuberculosis control measures, particularly in Ethiopia where tuberculosis is ...
Chilot Desta Agegnehu, Adugnaw Zeleke Alem   +1 more
doaj   +1 more source

Effect of BCG vaccination on proinflammatory responses in elderly individuals

Science Advances, 2021
BCG vaccination significantly diminished proinflammatory responses in elderly individuals in COVID-19 hot spots. We investigated the influence of Bacillus Calmette-Guérin (BCG) vaccination on the unstimulated plasma levels of a wide panel of cytokines ...
Nathella Pavankumar, C. Padmapriyadarsini, Anuradha Rajamanickam, Shrinivasa B. Marinaik, A. Nancy, S. Padmanaban, N. Akbar, M. Murhekar, S. Babu   +8 more
semanticscholar   +1 more source

BCG vaccination induces different cytokine profiles following infant BCG vaccination in the UK and Malawi [PDF]

, 2011
BACKGROUND: BCG vaccination of infants is thought to provide good protection in all settings. This study investigated whether Malawian infants made weaker responses across a cytokine panel after BCG vaccination, compared with UK infants.METHODS: Diluted ...
Hazel M. Dockrell, Newport, Melanie J, Mvula, Hazzie, Weir, Rosemary E., Rose Blitz, Fine, P.E., Steven G. Smith, Nuala McGrath (230042), Crampin, Amelia C, Keith Branson (239422), Hazel M Dockrell (10414616), Sian Floyd, Fine, Paul E, Crampin, Amelia C., Weir, R.E., McGrath, N., Floyd, Sian, Rose Blitz (356877), Newport, M.J., Anne Ben-Smith (244056), Melanie Newport (4461202), Lalor, Maeve K., Hazzie Mvula, Lalor, M.K., Maeve K Lalor (16181825), Sian Floyd (239400), Weir, Rosemary E, Lalor, Maeve K, Gorak-Stolinska, P., Fine, Paul E., Nuala McGrath, Crampin, A.C., Ben-Smith, A., Steven G Smith (16181831), Maeve K. Lalor, Hazzie Mvula (271278), Smith, S.G., Mvula, H., Smith, Steven G., Smith, Steven G, Patricia Gorak-Stolinska (356875), Floyd, S., Blitz, R., McGrath, Nuala, Amelia C. Crampin, Gorak-Stolinska, Patricia, Rosemary E. Weir, Branson, K., Amelia C Crampin (10281422), Ben-Smith, Anne, Dockrell, Hazel M., Paul E. Fine, Paul E Fine (16181834), Blitz, Rose, Dockrell, H.M., Rosemary E Weir (16181828), Keith Branson, Anne Ben-Smith, Dockrell, Hazel M, Newport, Melanie J., Branson, Keith, Patricia Gorak-Stolinska, Melanie J. Newport   +62 more
core   +1 more source

Influence of Aerosol Delivered BCG Vaccination on Immunological and Disease Parameters Following SARS-CoV-2 Challenge in Rhesus Macaques

Frontiers in Immunology, 2022
The tuberculosis vaccine, Bacille Calmette-Guerin (BCG), also affords protection against non-tuberculous diseases attributable to heterologous immune mechanisms such as trained innate immunity, activation of non-conventional T-cells, and cross-reactive ...
A. White, L. Sibley, C. Sarfas, Alexandra L. Morrison, K. Bewley, C. Churchward, S. Fotheringham, Konstantinos Gkolfinos, K. Gooch, Alastair Handley, H. Humphries, L. Hunter, Chelsea L. Kennard, S. Longet, Adam Mabbutt, M. Moffatt, E. Rayner, T. Tipton, Robert J. Watson, Y. Hall, M. Bodman-Smith, F. Gleeson, M. Dennis, F. Salguero, M. Carroll, H. McShane, W. Cookson, J. Hopkin, S. Sharpe   +28 more
semanticscholar   +1 more source

Persistence of the immune response induced by BCG vaccination. [PDF]

, 2008
BACKGROUND: Although BCG vaccination is recommended in most countries of the world, little is known of the persistence of BCG-induced immune responses. As novel TB vaccines may be given to boost the immunity induced by neonatal BCG vaccination, evidence ...
Paul EM Fine, Sally Stenson, Branson Keith, Rose Blitz, Stenson, Sally, Dockrell Hazel M, Hazel M Dockrell, Floyd Sian, Maeve K Lalor, Rosemary E Weir, Gorak-Stolinska, Patricia, Sian Floyd, Fine, Paul EM, Ben-Smith Anne, Ben-Smith, Anne, Weir Rosemary E, Floyd, Sian, Blitz, Rose, Lalor Maeve K, Weir, Rosemary E, Fine Paul EM, Keith Branson, Anne Ben-Smith, Stenson Sally, Gorak-Stolinska Patricia, Lalor, Maeve K, Dockrell, Hazel M, Branson, Keith, Patricia Gorak-Stolinska, Blitz Rose   +29 more
core   +1 more source

The association of Coronavirus Disease-19 mortality and prior bacille Calmette-Guerin vaccination: a robust ecological analysis using unsupervised machine learning

Scientific Reports, 2021
Population-level data have suggested that bacille Calmette-Guerin (BCG) vaccination may lessen the severity of Coronavirus Disease-19 (COVID-19) prompting clinical trials in this area. Some reports have demonstrated conflicting results.
Nathan A. Brooks, Ankur Puri, Sanya Garg, Swapnika Nag, Jacomo Corbo, Anas El Turabi, Noshir Kaka, Rodney W. Zemmel, Paul K. Hegarty, Ashish M. Kamat   +9 more
doaj   +1 more source