Genomic characteristics of two most widely used BCG vaccine strains: Danish 1331 and Pasteur 1173P2 [PDF]
BMC Genomics, 2022 Background Bacillus Calmette–Guérin (BCG) refers to a group of vaccine strains with unique genetic characteristics. BCG is the only available vaccine for preventing tuberculosis (TB).
Mahla Asadian +3 more
doaj +2 more sources
Culture filtrate proteins from BCG act as adjuvants for cytotoxic T lymphocyte induction
Frontiers in Immunology, 2023 Mycobacterium bovis bacilli Calmette-Guerin (BCG) is a licensed vaccine against tuberculosis. It requires attenuated live bacteria to be effective, possibly because actively secreted proteins play a critical role in inducing anti-tuberculosis immunity ...
Satoru Mizuno +7 more
doaj +1 more source
TUBERCULIN RESPONSE AND SCAR FORMATION IN BCG VACCINATED 7-YEARS OLD SCHOOLCHILDREN IN SOFIA, BULGARIA [PDF]
Journal of IMAB, 2015 This study has been designed to evaluate safety and efficacy of BCG vaccine in school-entering children in terms of tuberculin response to PPD and scar formation as indicators for successful vaccination.
Tzvetelina Stefanova
doaj +1 more source
Differential Adverse Event Profiles Associated with BCG as a Preventive Tuberculosis Vaccine or Therapeutic Bladder Cancer Vaccine Identified by Comparative Ontology-Based VAERS and Literature Meta-Analysis. [PDF]
PLoS ONE, 2016 M. bovis strain Bacillus Calmette-Guérin (BCG) has been the only licensed live attenuated vaccine against tuberculosis (TB) for nearly one century and has also been approved as a therapeutic vaccine for bladder cancer treatment since 1990.
Jiangan Xie +3 more
doaj +1 more source
Bacillus Calmette-Guérin vaccine-related complications in children in Oman
Annals of Saudi Medicine, 2021 BACKGROUND: Bacillus Calmette-Guérin (BCG) vaccine-related complications are frequently observed in children in Oman. There are a few regional studies on BCG complications, but none from Oman.
Badria Al Waili +4 more
doaj +1 more source
Frontiers in Immunology, 2022 Tuberculosis (TB) is a major global health problem and the only currently-licensed vaccine, BCG, is inadequate. Many TB vaccine candidates are designed to be given as a boost to BCG; an understanding of the BCG-induced immune response is therefore ...
Julia Bitencourt +19 more
doaj +1 more source
Non-Tuberculous Mycobacteria Interference with BCG-Current Controversies and Future Directions
Vaccines, 2020 The global tuberculosis (TB) epidemic caused by the bacterial pathogen Mycobacterium tuberculosis (M.tb) continues unabated. The Mycobacterium bovis bacillus Calmette–Guérin (BCG) vaccination is widely utilized worldwide to protect against infection with
Deepshikha Verma +2 more
doaj +1 more source
Past, Present and Future of Bacillus Calmette-Guérin Vaccine Use in China
Vaccines, 2022 The BCG vaccine is prepared from a weakened strain of Mycobacterium bovis (M. bovis), a bacterium closely related to Mycobacterium tuberculosis (MTB), which causes tuberculosis (TB).
Junli Li +4 more
doaj +1 more source
BCG: a vaccine with multiple faces
Human Vaccines & Immunotherapeutics, 2020 BCG has been recommended because of its efficacy against disseminated and meningeal tuberculosis. The BCG vaccine has other mechanisms of action besides tuberculosis protection, with immunomodulatory properties that are now being discovered. Reports have
Marco Antonio Yamazaki-Nakashimada +4 more
doaj +1 more source
Биопрепараты: Профилактика, диагностика, лечение, 2022 To date, the Bacillus Calmette–Guérin (BCG) vaccine has been the only medicinal product for active mass childhood immunisation against tuberculosis in the Russian Federation.
D. T. Levi +5 more
doaj +1 more source