Reference genome and comparative genome analysis for the WHO reference strain for Mycobacterium bovis BCG Danish, the present tuberculosis vaccine [PDF]
BMC Genomics, 2019 Background Mycobacterium bovis bacillus Calmette-Guérin (M. bovis BCG) is the only vaccine available against tuberculosis (TB). In an effort to standardize the vaccine production, three substrains, i.e.
Katlyn Borgers +9 more
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Genomic characteristics of two most widely used BCG vaccine strains: Danish 1331 and Pasteur 1173P2 [PDF]
BMC Genomics, 2022 Background Bacillus Calmette–Guérin (BCG) refers to a group of vaccine strains with unique genetic characteristics. BCG is the only available vaccine for preventing tuberculosis (TB).
Mahla Asadian +3 more
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Future Path Toward TB Vaccine Development: Boosting BCG or Re-educating by a New Subunit Vaccine [PDF]
Frontiers in Immunology, 2018 Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (Mtb), kills 5,000 people per day globally. Rapid development and spread of various multi drug-resistant strains of Mtb emphasize that an effective vaccine is still the most ...
Nancy Gupta +5 more
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Development and validation of BCG vaccine-induced novel granulomatous liver injury preclinical animal model. [PDF]
Animal Model Exp MedSharma S +8 more
europepmc +2 more sources
Development of a fast and precise potency test for BCG vaccine viability using flow cytometry compared to MTT and colony-forming unit assays. [PDF]
Sci Rep, 2023 Moghawry HM +4 more
europepmc +3 more sources
Culture filtrate proteins from BCG act as adjuvants for cytotoxic T lymphocyte induction
Frontiers in Immunology, 2023 Mycobacterium bovis bacilli Calmette-Guerin (BCG) is a licensed vaccine against tuberculosis. It requires attenuated live bacteria to be effective, possibly because actively secreted proteins play a critical role in inducing anti-tuberculosis immunity ...
Satoru Mizuno +7 more
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TUBERCULIN RESPONSE AND SCAR FORMATION IN BCG VACCINATED 7-YEARS OLD SCHOOLCHILDREN IN SOFIA, BULGARIA [PDF]
Journal of IMAB, 2015 This study has been designed to evaluate safety and efficacy of BCG vaccine in school-entering children in terms of tuberculin response to PPD and scar formation as indicators for successful vaccination.
Tzvetelina Stefanova
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Differential Adverse Event Profiles Associated with BCG as a Preventive Tuberculosis Vaccine or Therapeutic Bladder Cancer Vaccine Identified by Comparative Ontology-Based VAERS and Literature Meta-Analysis. [PDF]
PLoS ONE, 2016 M. bovis strain Bacillus Calmette-Guérin (BCG) has been the only licensed live attenuated vaccine against tuberculosis (TB) for nearly one century and has also been approved as a therapeutic vaccine for bladder cancer treatment since 1990.
Jiangan Xie +3 more
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Bacillus Calmette-Guérin vaccine-related complications in children in Oman
Annals of Saudi Medicine, 2021 BACKGROUND: Bacillus Calmette-Guérin (BCG) vaccine-related complications are frequently observed in children in Oman. There are a few regional studies on BCG complications, but none from Oman.
Badria Al Waili +4 more
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Frontiers in Immunology, 2022 Tuberculosis (TB) is a major global health problem and the only currently-licensed vaccine, BCG, is inadequate. Many TB vaccine candidates are designed to be given as a boost to BCG; an understanding of the BCG-induced immune response is therefore ...
Julia Bitencourt +19 more
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