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Differential Adverse Event Profiles Associated with BCG as a Preventive Tuberculosis Vaccine or Therapeutic Bladder Cancer Vaccine Identified by Comparative Ontology-Based VAERS and Literature Meta-Analysis. [PDF]
PLoS ONE, 2016 M. bovis strain Bacillus Calmette-Guérin (BCG) has been the only licensed live attenuated vaccine against tuberculosis (TB) for nearly one century and has also been approved as a therapeutic vaccine for bladder cancer treatment since 1990.
Jiangan Xie +3 more
doaj +1 more source
Bacillus Calmette-Guérin vaccine-related complications in children in Oman
Annals of Saudi Medicine, 2021 BACKGROUND: Bacillus Calmette-Guérin (BCG) vaccine-related complications are frequently observed in children in Oman. There are a few regional studies on BCG complications, but none from Oman.
Badria Al Waili +4 more
doaj +1 more source
BCG vaccine protection from severe coronavirus disease 2019 (COVID-19)
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance The COVID-19 pandemic is one of the most devastating in recent history. The bacillus Calmette−Guérin (BCG) vaccine against tuberculosis also confers broad protection against other infectious diseases, and it has been proposed that it could ...
L. Escobar +2 more
semanticscholar +1 more source
Journal of Internal Medicine, 2022 The Bacillus Calmette–Guérin (BCG) vaccine may confer cross‐protection against viral diseases in adults. This study evaluated BCG vaccine cross‐protection in adults with convalescent coronavirus disease 2019 (COVID‐19).
M. Jalalizadeh +13 more
semanticscholar +1 more source
Frontiers in Immunology, 2022 Tuberculosis (TB) is a major global health problem and the only currently-licensed vaccine, BCG, is inadequate. Many TB vaccine candidates are designed to be given as a boost to BCG; an understanding of the BCG-induced immune response is therefore ...
Julia Bitencourt +19 more
doaj +1 more source
A review of the BCG vaccine and other approaches toward tuberculosis eradication
Human Vaccines & Immunotherapeutics, 2021 Despite aggressive eradication efforts, Tuberculosis (TB) remains a global health burden, one that disproportionally affects poorer, less developed nations.
Thomas Cho +5 more
semanticscholar +1 more source
Reconcile the debate over protective effects of BCG vaccine against COVID-19
Scientific Reports, 2021 While awaiting the COVID-19 vaccines, researchers have been actively exploring the effectiveness of existing vaccines against the new virus, among which the BCG vaccine (Bacillus Calmette-Guérin) receives the most attention.
W. Fu +7 more
semanticscholar +1 more source
Non-Tuberculous Mycobacteria Interference with BCG-Current Controversies and Future Directions
Vaccines, 2020 The global tuberculosis (TB) epidemic caused by the bacterial pathogen Mycobacterium tuberculosis (M.tb) continues unabated. The Mycobacterium bovis bacillus Calmette–Guérin (BCG) vaccination is widely utilized worldwide to protect against infection with
Deepshikha Verma +2 more
doaj +1 more source
Past, Present and Future of Bacillus Calmette-Guérin Vaccine Use in China
Vaccines, 2022 The BCG vaccine is prepared from a weakened strain of Mycobacterium bovis (M. bovis), a bacterium closely related to Mycobacterium tuberculosis (MTB), which causes tuberculosis (TB).
Junli Li +4 more
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BCG: a vaccine with multiple faces
Human Vaccines & Immunotherapeutics, 2020 BCG has been recommended because of its efficacy against disseminated and meningeal tuberculosis. The BCG vaccine has other mechanisms of action besides tuberculosis protection, with immunomodulatory properties that are now being discovered. Reports have
Marco Antonio Yamazaki-Nakashimada +4 more
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