Results 31 to 40 of about 34,105 (239)

Evolution of the Bacillus Calmette-Guérin scar Russia and Moreau strains in newborns: A brazilian cohort

Vaccine: X, 2023
Background: In Brazil, in 1925, the Moreau strain was introduced, and since its implementation, it has been the routine vaccine for health services. Since 2013, many countries, including Brazil, have been experiencing problems with the production of ...
Ramon Andrade de Souza, Florisneide Rodrigues Barreto, Carlos Antônio de Souza Teles Santos, Joilda Silva Nery, Carla Cristina Oliveira de Jesus Lima, Isabella Soares Castelo, Marcio Natividade, Jacy Amaral Freire de Andrade, Maurício Lima Barreto, Susan Martins Pereira   +9 more
doaj   +1 more source

Persistence of the immune response induced by BCG vaccination. [PDF]

, 2008
BACKGROUND: Although BCG vaccination is recommended in most countries of the world, little is known of the persistence of BCG-induced immune responses. As novel TB vaccines may be given to boost the immunity induced by neonatal BCG vaccination, evidence ...
Paul EM Fine, Sally Stenson, Branson Keith, Rose Blitz, Stenson, Sally, Dockrell Hazel M, Hazel M Dockrell, Floyd Sian, Maeve K Lalor, Rosemary E Weir, Gorak-Stolinska, Patricia, Sian Floyd, Fine, Paul EM, Ben-Smith Anne, Ben-Smith, Anne, Weir Rosemary E, Floyd, Sian, Blitz, Rose, Lalor Maeve K, Weir, Rosemary E, Fine Paul EM, Keith Branson, Anne Ben-Smith, Stenson Sally, Gorak-Stolinska Patricia, Lalor, Maeve K, Dockrell, Hazel M, Branson, Keith, Patricia Gorak-Stolinska, Blitz Rose   +29 more
core   +1 more source

Time to face the proofs: the BCG Moreau vaccine promotes superior inflammatory cytokine profile in vitro when compared with Russia, Pasteur, and Danish strains

Human Vaccines & Immunotherapeutics, 2022
Tuberculosis (TB) has been a major public health problem worldwide, and the Bacillus Calmette–Guérin (BCG) vaccine is the only available vaccine against this disease. The BCG vaccine is no longer a single organism; it consists of diverse strains.
Andreon Santos Machado da Silva, Lawrence Henrique Paz Albuquerque, Carlos Germano Garrido de Ponte, Matheus Rogério de Almeida, Sandra Elizabete Ribeiro de Faria, Mariana da Silva Ribeiro, Evelyn Nunes Goulart da Silva Pereira, Paulo Renato Zuquim Antas   +7 more
doaj   +1 more source

Listeria-Vectored Multiantigenic Tuberculosis Vaccine Enhances Protective Immunity against Aerosol Challenge with Virulent Mycobacterium tuberculosis in BCG-Immunized C57BL/6 and BALB/c Mice

mBio, 2022
Mycobacterium tuberculosis infects approximately one-third of the world's population, causing active tuberculosis (TB) in ~10 million people and death in ~1.5 million people annually. A potent vaccine is needed to boost the level of immunity conferred by
Qingmei Jia, Saša Masleša-Galić, Susana Nava, Marcus A. Horwitz   +3 more
doaj   +1 more source

Future Path Toward TB Vaccine Development: Boosting BCG or Re-educating by a New Subunit Vaccine

Frontiers in Immunology, 2018
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (Mtb), kills 5,000 people per day globally. Rapid development and spread of various multi drug-resistant strains of Mtb emphasize that an effective vaccine is still the most ...
Nancy Gupta, Saurabh Garg, Satish Vedi, Dennis Y. Kunimoto, Rakesh Kumar, Babita Agrawal   +5 more
doaj   +1 more source

Immunogenicity of Danish-SSI 1331 BCG vaccine in the UK: comparison with Glaxo-Evans 1077 BCG vaccine.

, 2006
The immunogenicity and reactogenicity, in British schoolchildren, of the newly introduced Danish-SSI 1331 BCG vaccine was compared with that of the previously used Glaxo-Evans 1077 BCG vaccine. Interferon-gamma (IFN-gamma) response to M.
Fine, Paul EM, Weir, Rosemary E, Ben-Smith, Anne, Stenson, Sally, Floyd, Sian, Luke, Sarah, Blitz, Rose, Lalor, Maeve K, Dockrell, Hazel M, Gorak-Stolinska, Patricia, Branson, Keith, Nazareth, Bernadette   +11 more
core   +1 more source

Research progress in the off-target effects of Bacille Calmette–Guérin vaccine

Chinese Medical Journal
. Bacille Calmette–Guérin (BCG) vaccine is designed to provide protection against tuberculosis (TB). However, numerous epidemiological, clinical, and immunological studies have shown that BCG vaccination affects neonatal and infant mortality, which may ...
Yanfei Wu, Xiaoyin Zhang, Li Zhou, Jiayu Lu, Fengcai Zhu, Jingxin Li, Jing Ni, Xuehong Zhang   +7 more
doaj   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

BCG vaccination: a role for vitamin D? [PDF]

, 2011
BCG vaccination is administered in infancy in most countries with the aim of providing protection against tuberculosis. There is increasing interest in the role of vitamin D in immunity to tuberculosis.
Hazel M. Dockrell, Rose Blitz, Branson Keith, Maeve K. Lalor, Blitz, R, Lalor Maeve K., Fine Paul E., Branson, K, Hazel M Dockrell, Maeve K Lalor, Floyd Sian, Fine, PE, Rosemary E Weir, Weir, RE, Gorak-Stolinska, Patricia, Rosemary E. Weir, Sian Floyd, Fine, Paul E, Lalor, MK, Floyd, Sian, Paul E. Fine, Blitz, Rose, Dockrell Hazel M., Weir, Rosemary E, Keith Branson, Paul E Fine, Weir Rosemary E., Gorak-Stolinska, P, Dockrell, HM, Gorak-Stolinska Patricia, Lalor, Maeve K, Dockrell, Hazel M, Branson, Keith, Patricia Gorak-Stolinska, Floyd, S, Blitz Rose   +35 more
core   +1 more source