Results 31 to 40 of about 55,251 (223)
Screening vaccine formulations for biological activity using fresh human whole blood. [PDF]
, 2014 Understanding the relevant biological activity of any pharmaceutical formulation destined for human use is crucial. For vaccine-based formulations, activity must reflect the expected immune response, while for non-vaccine therapeutic agents, such as ...
Aboutorabian, Sepideh +9 more
core +1 more source
A systematic review of the impact of psychosocial factors on immunity: Implications for enhancing BCG response against tuberculosis. [PDF]
, 2019 Background: Tuberculosis (TB) remains an urgent global public health priority, causing 1.5 million deaths worldwide in 2018. There is evidence that psychosocial factors modulate immune function; however, how this may influence TB risk or BCG vaccine ...
Boccia, D +5 more
core +2 more sources
Features of General Reactive Potential of the Body in Infants with BCG lymphadenitis
Aktualʹnaâ Infektologiâ, 2014 Objective: integrated health assessment of infants with BCG-induced regional lymphadenitis. Material and Methods. The work was carried out on the academic basis of pediatric infectious departments of Donetsk region and Donetsk regional laboratory center ...
A.I. Bobrovitskaia +3 more
doaj +1 more source
BCG vaccination strategies against tuberculosis: updates and perspectives
Human Vaccines & Immunotherapeutics, 2021 Bacillus Calmette-Guérin (BCG) is the only licensed vaccine against tuberculosis (TB). However, BCG has variable efficacy and cannot completely prevent TB infection and transmission.
Mengjin Qu, Xiangmei Zhou, Hao Li
doaj +1 more source
BCG vaccine reactivation after mRNA immunization against COVID-19: case report
Revista Médica de Minas Gerais, 2023 The Bacillus Calmette-Guérin (BCG) vaccine is a live attenuated pathogen vaccine used to prevent severe types of tuberculosis. A related immunological event is its scar reactivation.
José Paulo Ribeiro Júnior +3 more
doaj +1 more source
Vaccine coverage and determinants of incomplete vaccination in children aged 12-23 months in dschang, west region, cameroon: a cross-sectional survey during a polio outbreak [PDF]
, 2015 Inadequate immunization coverage with increased risk of vaccine preventable diseases outbreaksremains a problem in Africa. Moreover, different factors contribute to incomplete vaccination status. This study wasperformed in Dschang (West Region, Cameroon),
Biguioh, Rodrigue Mabvouna +8 more
core +2 more sources
mBio, 2022 Mycobacterium tuberculosis infects approximately one-third of the world's population, causing active tuberculosis (TB) in ~10 million people and death in ~1.5 million people annually. A potent vaccine is needed to boost the level of immunity conferred by
Qingmei Jia +3 more
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2022 Tuberculosis (TB) has been a major public health problem worldwide, and the Bacillus Calmette–Guérin (BCG) vaccine is the only available vaccine against this disease. The BCG vaccine is no longer a single organism; it consists of diverse strains.
Andreon Santos Machado da Silva +7 more
doaj +1 more source
Vaccine: X, 2023 Background: In Brazil, in 1925, the Moreau strain was introduced, and since its implementation, it has been the routine vaccine for health services. Since 2013, many countries, including Brazil, have been experiencing problems with the production of ...
Ramon Andrade de Souza +9 more
doaj +1 more source
Future Path Toward TB Vaccine Development: Boosting BCG or Re-educating by a New Subunit Vaccine
Frontiers in Immunology, 2018 Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (Mtb), kills 5,000 people per day globally. Rapid development and spread of various multi drug-resistant strains of Mtb emphasize that an effective vaccine is still the most ...
Nancy Gupta +5 more
doaj +1 more source