Results 31 to 40 of about 420,990 (225)

BCG vaccine reactivation after mRNA immunization against COVID-19: case report

Revista Médica de Minas Gerais, 2023
The Bacillus Calmette-Guérin (BCG) vaccine is a live attenuated pathogen vaccine used to prevent severe types of tuberculosis. A related immunological event is its scar reactivation.
José Paulo Ribeiro Júnior, Maria do Carmo Araújo Palmeira Queiroz, Arnoud de Lucena Flor, Clause Willdys Medeiros Dantas   +3 more
doaj   +1 more source

The influence of prior exposure to environmental mycobacteria on the IFN-(gamma) response to BCG vaccination in southern England and northern Malaw [PDF]

, 2006
We report a large study of the effect of BCG vaccination on the in vitro 6-day whole blood interferon-gamma (IFN-γ) response to antigens from eight species of mycobacteria among schoolchildren in south-eastern England, where bacille Calmette–Guérin (
Donovan, L, Black, G, Nazareth, B, Sichali, L, Chaguluka, S, Weir, R, Stenson, S, Branson, K, Crampin, A, Dockrell, HM, Stanley, C, Floyd, S, Fine, P   +12 more
core   +2 more sources

Time to face the proofs: the BCG Moreau vaccine promotes superior inflammatory cytokine profile in vitro when compared with Russia, Pasteur, and Danish strains

Human Vaccines & Immunotherapeutics, 2022
Tuberculosis (TB) has been a major public health problem worldwide, and the Bacillus Calmette–Guérin (BCG) vaccine is the only available vaccine against this disease. The BCG vaccine is no longer a single organism; it consists of diverse strains.
Andreon Santos Machado da Silva, Lawrence Henrique Paz Albuquerque, Carlos Germano Garrido de Ponte, Matheus Rogério de Almeida, Sandra Elizabete Ribeiro de Faria, Mariana da Silva Ribeiro, Evelyn Nunes Goulart da Silva Pereira, Paulo Renato Zuquim Antas   +7 more
doaj   +1 more source

Listeria-Vectored Multiantigenic Tuberculosis Vaccine Enhances Protective Immunity against Aerosol Challenge with Virulent Mycobacterium tuberculosis in BCG-Immunized C57BL/6 and BALB/c Mice

mBio, 2022
Mycobacterium tuberculosis infects approximately one-third of the world's population, causing active tuberculosis (TB) in ~10 million people and death in ~1.5 million people annually. A potent vaccine is needed to boost the level of immunity conferred by
Qingmei Jia, Saša Masleša-Galić, Susana Nava, Marcus A. Horwitz   +3 more
doaj   +1 more source

Future Path Toward TB Vaccine Development: Boosting BCG or Re-educating by a New Subunit Vaccine

Frontiers in Immunology, 2018
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (Mtb), kills 5,000 people per day globally. Rapid development and spread of various multi drug-resistant strains of Mtb emphasize that an effective vaccine is still the most ...
Nancy Gupta, Saurabh Garg, Satish Vedi, Dennis Y. Kunimoto, Rakesh Kumar, Babita Agrawal   +5 more
doaj   +1 more source

Evolution of the Bacillus Calmette-Guérin scar Russia and Moreau strains in newborns: A brazilian cohort

Vaccine: X, 2023
Background: In Brazil, in 1925, the Moreau strain was introduced, and since its implementation, it has been the routine vaccine for health services. Since 2013, many countries, including Brazil, have been experiencing problems with the production of ...
Ramon Andrade de Souza, Florisneide Rodrigues Barreto, Carlos Antônio de Souza Teles Santos, Joilda Silva Nery, Carla Cristina Oliveira de Jesus Lima, Isabella Soares Castelo, Marcio Natividade, Jacy Amaral Freire de Andrade, Maurício Lima Barreto, Susan Martins Pereira   +9 more
doaj   +1 more source

BCG vaccine in Korea

Clinical and Experimental Vaccine Research, 2013
The anti-tuberculosis Bacille de Calmette et Guérin (BCG) vaccine was developed between 1905 and 1921 at Pasteur Institutes of Lille in France, and was adopted by many countries. BCG strains comprise natural mutants of major virulence factors of Mycobacterium tuberculosis and that BCG sub-strains differ markedly in virulence levels.
Joung, Sun Myung, Ryoo, Sungweon
openaire   +2 more sources

Immunogenicity of Danish-SSI 1331 BCG vaccine in the UK: comparison with Glaxo-Evans 1077 BCG vaccine.

, 2006
The immunogenicity and reactogenicity, in British schoolchildren, of the newly introduced Danish-SSI 1331 BCG vaccine was compared with that of the previously used Glaxo-Evans 1077 BCG vaccine. Interferon-gamma (IFN-gamma) response to M.
Fine, Paul EM, Weir, Rosemary E, Ben-Smith, Anne, Stenson, Sally, Floyd, Sian, Luke, Sarah, Blitz, Rose, Lalor, Maeve K, Dockrell, Hazel M, Gorak-Stolinska, Patricia, Branson, Keith, Nazareth, Bernadette   +11 more
core   +1 more source

Persistence of the immune response induced by BCG vaccination. [PDF]

, 2008
BACKGROUND: Although BCG vaccination is recommended in most countries of the world, little is known of the persistence of BCG-induced immune responses. As novel TB vaccines may be given to boost the immunity induced by neonatal BCG vaccination, evidence ...
Paul EM Fine, Sally Stenson, Branson Keith, Rose Blitz, Stenson, Sally, Dockrell Hazel M, Hazel M Dockrell, Floyd Sian, Maeve K Lalor, Rosemary E Weir, Gorak-Stolinska, Patricia, Sian Floyd, Fine, Paul EM, Ben-Smith Anne, Ben-Smith, Anne, Weir Rosemary E, Floyd, Sian, Blitz, Rose, Lalor Maeve K, Weir, Rosemary E, Fine Paul EM, Keith Branson, Anne Ben-Smith, Stenson Sally, Gorak-Stolinska Patricia, Lalor, Maeve K, Dockrell, Hazel M, Branson, Keith, Patricia Gorak-Stolinska, Blitz Rose   +29 more
core   +1 more source

Safety and immunogenicity of boosting BCG vaccinated subjects with BCG: Comparison with boosting with a new TB vaccine, MVA85A [PDF]

, 2009
Objectives: To investigate the safety and immunogenicity of a booster BCG vaccination delivered intradermally in healthy, BCG vaccinated subjects and to compare with a previous clinical trial where BCG vaccinated subjects were boosted with a new TB ...
Whelan, KT, Pathan, Ansar A, Poulton Ian, Nicola C Alder, Sander Clare R., Whelan, Kathryn T, Kathryn T Whelan, Fletcher, Helen A, Hill, AVS, Alder, NC, Fletcher, HA, Pathan Ansar A., Hill, Adrian VS, Sander, CR, Hill Adrian V. S., McShane Helen, Pathan, AA, Alder, Nicola C, Clare R Sander, Helen McShane, Ansar A Pathan, Ian Poulton, Poulton, Ian, Alder Nicola C., Whelan Kathryn T., Poulton, I, Sander, Clare R, Adrian V S Hill, Helen A Fletcher, Fletcher Helen A., McShane, H, McShane, Helen   +31 more
core   +1 more source