Results 31 to 40 of about 389,087 (235)

Persistence of the immune response induced by BCG vaccination. [PDF]

, 2008
BACKGROUND: Although BCG vaccination is recommended in most countries of the world, little is known of the persistence of BCG-induced immune responses. As novel TB vaccines may be given to boost the immunity induced by neonatal BCG vaccination, evidence ...
Paul EM Fine, Sally Stenson, Branson Keith, Rose Blitz, Stenson, Sally, Dockrell Hazel M, Hazel M Dockrell, Floyd Sian, Maeve K Lalor, Rosemary E Weir, Gorak-Stolinska, Patricia, Sian Floyd, Fine, Paul EM, Ben-Smith Anne, Ben-Smith, Anne, Weir Rosemary E, Floyd, Sian, Blitz, Rose, Lalor Maeve K, Weir, Rosemary E, Fine Paul EM, Keith Branson, Anne Ben-Smith, Stenson Sally, Gorak-Stolinska Patricia, Lalor, Maeve K, Dockrell, Hazel M, Branson, Keith, Patricia Gorak-Stolinska, Blitz Rose   +29 more
core   +1 more source

The effect of birth weight and gestational age on BCG-induced immune responses in infants following BCG vaccination [PDF]

, 2010
Includes bibliographical references (leaves 102-114).Bacillus Calmette?Gu?rin (BCG), the only currently licensed tuberculosis (TB) vaccine, provides variable efficacy. Despite the use of BCG, TB remains a global health problem.
Dube, Frederick
core   +1 more source

Listeria-Vectored Multiantigenic Tuberculosis Vaccine Enhances Protective Immunity against Aerosol Challenge with Virulent Mycobacterium tuberculosis in BCG-Immunized C57BL/6 and BALB/c Mice

mBio, 2022
Mycobacterium tuberculosis infects approximately one-third of the world's population, causing active tuberculosis (TB) in ~10 million people and death in ~1.5 million people annually. A potent vaccine is needed to boost the level of immunity conferred by
Qingmei Jia, Saša Masleša-Galić, Susana Nava, Marcus A. Horwitz   +3 more
doaj   +1 more source

Polyantigenic Interferon-γ Responses are Associated with Protection from TB Among HIV-Infected Adults with Childhood BCG Immunization. [PDF]

, 2011
Surrogate immunologic markers for natural and vaccine-mediated protection against tuberculosis (TB) have not been identified. HIV-infected adults with childhood BCG immunization entering the placebo arm of the DarDar TB vaccine trial in Dar es Salaam ...
Horsburgh, C Robert, Jenni M. Vuola, Mtei, L., Bakari, M, Pallangyo, K., Mitchell, B.K., Arbeit, R.D., C. Robert Horsburgh, Bakari, Muhammad, Matee, Mecky, C. Fordham von Reyn, Lillian Mtei, Sheth, S., Robert D Arbeit, Arbeit, Robert D, Mtei, Lillian, Mitchell, Brian K, C. Robert Horsburgh5, Muhammad Bakari, MacKenzie, T, Lahey, Timothy, Robert D. Arbeit, Todd MacKenzie, C. Fordham von Reyn1, Matee, M., Sheth, Siddharth, Brian K. Mitchell, Horsburgh, C.R., Vuola, Jenni M, Siddharth Sheth, Mecky Matee, Timothy Lahey, Pallangyo, Kisali, Jenni M Vuola, Kisali Pallangyo, C Fordham von Reyn, von Reyn, C.F., MacKenzie, Todd, Lahey, T., Vuola, J.M., von Reyn, C Fordham, C Robert Horsburgh, Brian K Mitchell   +42 more
core   +2 more sources

Future Path Toward TB Vaccine Development: Boosting BCG or Re-educating by a New Subunit Vaccine

Frontiers in Immunology, 2018
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (Mtb), kills 5,000 people per day globally. Rapid development and spread of various multi drug-resistant strains of Mtb emphasize that an effective vaccine is still the most ...
Nancy Gupta, Saurabh Garg, Satish Vedi, Dennis Y. Kunimoto, Rakesh Kumar, Babita Agrawal   +5 more
doaj   +1 more source

Evolution of the Bacillus Calmette-Guérin scar Russia and Moreau strains in newborns: A brazilian cohort

Vaccine: X, 2023
Background: In Brazil, in 1925, the Moreau strain was introduced, and since its implementation, it has been the routine vaccine for health services. Since 2013, many countries, including Brazil, have been experiencing problems with the production of ...
Ramon Andrade de Souza, Florisneide Rodrigues Barreto, Carlos Antônio de Souza Teles Santos, Joilda Silva Nery, Carla Cristina Oliveira de Jesus Lima, Isabella Soares Castelo, Marcio Natividade, Jacy Amaral Freire de Andrade, Maurício Lima Barreto, Susan Martins Pereira   +9 more
doaj   +1 more source

BCG vaccine in Korea

Clinical and Experimental Vaccine Research, 2013
The anti-tuberculosis Bacille de Calmette et Guérin (BCG) vaccine was developed between 1905 and 1921 at Pasteur Institutes of Lille in France, and was adopted by many countries. BCG strains comprise natural mutants of major virulence factors of Mycobacterium tuberculosis and that BCG sub-strains differ markedly in virulence levels.
Joung, Sun Myung, Ryoo, Sungweon
openaire   +2 more sources

Immunogenicity of Danish-SSI 1331 BCG vaccine in the UK: comparison with Glaxo-Evans 1077 BCG vaccine.

, 2006
The immunogenicity and reactogenicity, in British schoolchildren, of the newly introduced Danish-SSI 1331 BCG vaccine was compared with that of the previously used Glaxo-Evans 1077 BCG vaccine. Interferon-gamma (IFN-gamma) response to M.
Fine, Paul EM, Weir, Rosemary E, Ben-Smith, Anne, Stenson, Sally, Floyd, Sian, Luke, Sarah, Blitz, Rose, Lalor, Maeve K, Dockrell, Hazel M, Gorak-Stolinska, Patricia, Branson, Keith, Nazareth, Bernadette   +11 more
core   +1 more source

BCG vaccination induces different cytokine profiles following infant BCG vaccination in the UK and Malawi [PDF]

, 2011
BACKGROUND: BCG vaccination of infants is thought to provide good protection in all settings. This study investigated whether Malawian infants made weaker responses across a cytokine panel after BCG vaccination, compared with UK infants.METHODS: Diluted ...
Hazel M. Dockrell, Newport, Melanie J, Mvula, Hazzie, Weir, Rosemary E., Rose Blitz, Fine, P.E., Steven G. Smith, Nuala McGrath (230042), Crampin, Amelia C, Keith Branson (239422), Hazel M Dockrell (10414616), Sian Floyd, Fine, Paul E, Crampin, Amelia C., Weir, R.E., McGrath, N., Floyd, Sian, Rose Blitz (356877), Newport, M.J., Anne Ben-Smith (244056), Melanie Newport (4461202), Lalor, Maeve K., Hazzie Mvula, Lalor, M.K., Maeve K Lalor (16181825), Sian Floyd (239400), Weir, Rosemary E, Lalor, Maeve K, Gorak-Stolinska, P., Fine, Paul E., Nuala McGrath, Crampin, A.C., Ben-Smith, A., Steven G Smith (16181831), Maeve K. Lalor, Hazzie Mvula (271278), Smith, S.G., Mvula, H., Smith, Steven G., Smith, Steven G, Patricia Gorak-Stolinska (356875), Floyd, S., Blitz, R., McGrath, Nuala, Amelia C. Crampin, Gorak-Stolinska, Patricia, Rosemary E. Weir, Branson, K., Amelia C Crampin (10281422), Ben-Smith, Anne, Dockrell, Hazel M., Paul E. Fine, Paul E Fine (16181834), Blitz, Rose, Dockrell, H.M., Rosemary E Weir (16181828), Keith Branson, Anne Ben-Smith, Dockrell, Hazel M, Newport, Melanie J., Branson, Keith, Patricia Gorak-Stolinska, Melanie J. Newport   +62 more
core   +1 more source

Research progress in the off-target effects of Bacille Calmette–Guérin vaccine

Chinese Medical Journal
. Bacille Calmette–Guérin (BCG) vaccine is designed to provide protection against tuberculosis (TB). However, numerous epidemiological, clinical, and immunological studies have shown that BCG vaccination affects neonatal and infant mortality, which may ...
Yanfei Wu, Xiaoyin Zhang, Li Zhou, Jiayu Lu, Fengcai Zhu, Jingxin Li, Jing Ni, Xuehong Zhang   +7 more
doaj   +1 more source