Results 31 to 40 of about 723,552 (238)

Complete Genome Sequence, Genome Stability and Phylogeny of the Vaccine Strain Mycobacterium bovis BCG SL222 Sofia

Vaccines, 2021
Mycobacterium bovis bacillus Calmette–Guérin (BCG) is the only live attenuated vaccine available against tuberculosis. The first BCG vaccination was done exactly 100 years ago, in 1921.
Stefan Panaiotov, Yordan Hodzhev, Vladimir Tolchkov, Borislava Tsafarova, Alexander Mihailov, Tzvetelina Stefanova   +5 more
doaj   +1 more source

BCG Vaccines

Microbiology Spectrum, 2014
ABSTRACT BCG is the collective name for a family of live attenuated strains of Mycobacterium bovis that are currently used as the only vaccine against tuberculosis (TB). There are two major reasons for studying the genome of these organisms: (i) Because they are attenuated, BCG vaccines provide a window ...
Vanessa, Tran, Jun, Liu, Marcel A, Behr
openaire   +2 more sources

BCG Vaccine Derived Peptides Induce SARS-CoV-2 T Cell Cross-Reactivity

Frontiers in Immunology, 2020
Epidemiological studies and clinical trials suggest Bacillus Calmette-Guérin (BCG) vaccine has protective effects against coronavirus disease 2019 (COVID-19).
P. Eggenhuizen, B. H. Ng, Janet Chang, Ashleigh L. Fell, W. Wong, P. Gan, S. Holdsworth, J. Ooi   +7 more
semanticscholar   +1 more source

Features of General Reactive Potential of the Body in Infants with BCG lymphadenitis

Aktualʹnaâ Infektologiâ, 2014
Objective: integrated health assessment of infants with BCG-induced regional lymphadenitis. Material and Methods. The work was carried out on the academic basis of pediatric infectious departments of Donetsk region and Donetsk regional laboratory center ...
A.I. Bobrovitskaia, T.F. Golubova, V.V. Suhodolskaia, L.A. Zakharova   +3 more
doaj   +1 more source

BCG vaccine may generate cross-reactive T cells against SARS-CoV-2: In silico analyses and a hypothesis

Vaccine, 2020
Highlights • BCG contains similar 9-amino acid sequences with SARS-CoV-2.• The peptides have moderate to high binding affinity to common HLA class I molecules.• Cross-reactive T cells against SARS-CoV-2 could be generated by BCG vaccination.
Y. Tomita, R. Sato, T. Ikeda, T. Sakagami   +3 more
semanticscholar   +1 more source

BCG vaccination strategies against tuberculosis: updates and perspectives

Human Vaccines & Immunotherapeutics, 2021
Bacillus Calmette-Guérin (BCG) is the only licensed vaccine against tuberculosis (TB). However, BCG has variable efficacy and cannot completely prevent TB infection and transmission.
Mengjin Qu, Xiangmei Zhou, Hao Li
doaj   +1 more source

BCG vaccine reactivation after mRNA immunization against COVID-19: case report

Revista Médica de Minas Gerais, 2023
The Bacillus Calmette-Guérin (BCG) vaccine is a live attenuated pathogen vaccine used to prevent severe types of tuberculosis. A related immunological event is its scar reactivation.
José Paulo Ribeiro Júnior, Maria do Carmo Araújo Palmeira Queiroz, Arnoud de Lucena Flor, Clause Willdys Medeiros Dantas   +3 more
doaj   +1 more source

Reference genome and comparative genome analysis for the WHO reference strain for Mycobacterium bovis BCG Danish, the present tuberculosis vaccine

BMC Genomics, 2019
Background Mycobacterium bovis bacillus Calmette-Guérin (M. bovis BCG) is the only vaccine available against tuberculosis (TB). In an effort to standardize the vaccine production, three substrains, i.e.
Katlyn Borgers, Jheng-Yang Ou, Po-Xing Zheng, Petra Tiels, Annelies Van Hecke, Evelyn Plets, Gitte Michielsen, Nele Festjens, Nico Callewaert, Yao-Cheng Lin   +9 more
doaj   +1 more source

Time to face the proofs: the BCG Moreau vaccine promotes superior inflammatory cytokine profile in vitro when compared with Russia, Pasteur, and Danish strains

Human Vaccines & Immunotherapeutics, 2022
Tuberculosis (TB) has been a major public health problem worldwide, and the Bacillus Calmette–Guérin (BCG) vaccine is the only available vaccine against this disease. The BCG vaccine is no longer a single organism; it consists of diverse strains.
Andreon Santos Machado da Silva, Lawrence Henrique Paz Albuquerque, Carlos Germano Garrido de Ponte, Matheus Rogério de Almeida, Sandra Elizabete Ribeiro de Faria, Mariana da Silva Ribeiro, Evelyn Nunes Goulart da Silva Pereira, Paulo Renato Zuquim Antas   +7 more
doaj   +1 more source

Listeria-Vectored Multiantigenic Tuberculosis Vaccine Enhances Protective Immunity against Aerosol Challenge with Virulent Mycobacterium tuberculosis in BCG-Immunized C57BL/6 and BALB/c Mice

mBio, 2022
Mycobacterium tuberculosis infects approximately one-third of the world's population, causing active tuberculosis (TB) in ~10 million people and death in ~1.5 million people annually. A potent vaccine is needed to boost the level of immunity conferred by
Qingmei Jia, Saša Masleša-Galić, Susana Nava, Marcus A. Horwitz   +3 more
doaj   +1 more source