Results 51 to 60 of about 389,087 (235)

New tuberculosis vaccines in India: modelling the potential health and economic impacts of adolescent/adult vaccination with M72/AS01E and BCG-revaccination

BMC Medicine, 2023
Background India had an estimated 2.9 million tuberculosis cases and 506 thousand deaths in 2021. Novel vaccines effective in adolescents and adults could reduce this burden.
Rebecca A. Clark, Chathika K. Weerasuriya, Allison Portnoy, Christinah Mukandavire, Matthew Quaife, Roel Bakker, Danny Scarponi, Rebecca C. Harris, Kirankumar Rade, Sanjay Kumar Mattoo, Dheeraj Tumu, Nicolas A. Menzies, Richard G. White   +12 more
doaj   +1 more source

Vaccination in pediatric transplantation—General recommendations. A position paper by the European Reference Network TransplantChild

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Infectious diseases remain a leading cause of morbidity and mortality among pediatric transplant recipients, despite significant advances in transplantation management. Vaccination is the most effective strategy to prevent infections; however, its efficacy is hindered in solid organ transplant (SOT) and hematopoietic stem cell transplant (HSCT)
Valeria Casotti, Francesco Saglio, Adriana Balduzzi, Peter Barany, Vibeke Brix Christensen, Simona Buelli, Daniele Donà, Maja Klaudel‐Dreszler, Sara Mosca, Andrea Pietrobattista, Michele Pinon, Giusy Ranucci, Lars Wennberg, Lorenzo D'Antiga, ERN TransplantChild Working Group, Claudia Vittori, Manuela Tumino, B. Ruben Brandsema, Lisa Swartling, Silvia Garazzino, Carlo Pace Napoleone, Kai Lehmberg, Isabella Guzzo, Charlotte Roy, Nicola Pradegan, Silvia Simo Nebot, Maria Herthelius, Angelo Mazza, Enrico Aidala, Oleg Godik, Victoria Bordon Cueto De Braem, Marco Busutti, Emily Claire Argento, Marc Garcia Lorenzo, Timo Jahnukainen, Zoryana Ivanyuk   +35 more
wiley   +1 more source

Association between BCG-induced immunity and risk of TB disease [PDF]

, 2011
We tested the hypothesis that a lower frequency and profile of specific T cells induced by BCG vaccination at birth is associated with subsequent risk of developing ...
Kagina, Benjamin Mugo
core   +1 more source

Use of BCG vaccine for enhancement the immune response of sheep to Rev.1 Vaccination [PDF]

Journal of Veterinary Medical Research, 2008
This study was conducted to evaluate the protective effect of Brucella melitensis Rev.1 and the use of BCG vaccine as immunostimulant by subcutaneous injection in Guinea pigs. Lab.
S. M. S. El-Ayouby, O. R. Salib, H. K. El-Deen   +2 more
doaj   +1 more source

Investigating Tuberculosis Dynamics Under Various Control Strategies: A Comprehensive Analysis Using Real Statistical Data

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In the present investigation, a mathematical model with vaccination, treatment, and environmental impact under real data is presented. Initially, we present the model without any interventions, followed by an examination of its equilibrium points.
Bashir Al‐Hdaibat, Mahmoud H. DarAssi, Irfan Ahmad, Muhammad Altaf Khan, Reem Algethamie   +4 more
wiley   +1 more source

Immunogenicity of mannan derived from Mycobacterium bovis as a promising adjuvant in vaccine BCG

Iranian Journal of Microbiology
Background and Objectives: Lipoarabinomannan is one of the components of the significant structural cell surfaces of mycobacteria and serves as an immunostimulatory factor.
Rajab Mardani, Ariana Alavi, Seyed Dawood Mousavi Nasab, Nayebali Ahmadi, Mohammad Javad Hossein Tehrani, Maryam Shahali, Delaram Doroud   +6 more
doaj   +1 more source

The double-sided effects of Mycobacterium Bovis bacillus Calmette–Guérin vaccine

npj Vaccines, 2021
Bacillus Calmette–Guérin (BCG), the only vaccine proven to be effective against tuberculosis (TB), is the most commonly used vaccine globally. In addition to its effects on mycobacterial diseases, an increasing amount of epidemiological and experimental ...
Junli Li, Lingjun Zhan, Chuan Qin
doaj   +1 more source

The BCG Vaccine for COVID-19: First Verdict and Future Directions

Frontiers in Immunology, 2021
Despite of the rapid development of the vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it will take several months to have enough doses and the proper infrastructure to vaccinate a good proportion of the world ...
Maria Gonzalez-Perez, Rodrigo Sanchez-Tarjuelo, Boris Shor, Estanislao Nistal-Villan, Estanislao Nistal-Villan, Jordi Ochando, Jordi Ochando   +6 more
doaj   +1 more source

Advances in γδ T Cells: Cutaneous Biology and Therapeutic Potential for Skin Neoplasms

The Journal of Dermatology, EarlyView.
ABSTRACT γδ T cells represent an increasingly important subset of T lymphocytes in the immune response to cancer and as a platform for novel immunotherapies. The aim of this review is to synthesize recent insights into the biology and advances in therapeutic applications of γδ T cells in cutaneous malignancies, especially melanoma, within a framework ...
Simo Du, Anika Jallorina, Toru Yoshino, Lingyu Bao, Han Bao, Victor Chang, Henry K. Wong, Derek V. Chan, Stephen K. Richardson, Mary F. Lee‐Wong   +9 more
wiley   +1 more source

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source