Results 41 to 50 of about 723,552 (238)

BCG vaccine-induced protection from COVID-19 infection, wishful thinking or a game changer?

open access: yesmedRxiv, 2020
A series of epidemiological explorations have suggested a negative association between national BCG vaccination policy and the prevalence and mortality of COVID-19.
Luis E. Escobar   +2 more
semanticscholar   +1 more source

Evolution of the Bacillus Calmette-Guérin scar Russia and Moreau strains in newborns: A brazilian cohort

open access: yesVaccine: X, 2023
Background: In Brazil, in 1925, the Moreau strain was introduced, and since its implementation, it has been the routine vaccine for health services. Since 2013, many countries, including Brazil, have been experiencing problems with the production of ...
Ramon Andrade de Souza   +9 more
doaj   +1 more source

Future Path Toward TB Vaccine Development: Boosting BCG or Re-educating by a New Subunit Vaccine

open access: yesFrontiers in Immunology, 2018
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (Mtb), kills 5,000 people per day globally. Rapid development and spread of various multi drug-resistant strains of Mtb emphasize that an effective vaccine is still the most ...
Nancy Gupta   +5 more
doaj   +1 more source

Efficacy and Safety of BCG Vaccine for Control of Tuberculosis in Domestic Livestock and Wildlife

open access: yesFrontiers in Veterinary Science, 2018
Bovine tuberculosis (TB) continues to be an intractable problem in many countries, particularly where “test and slaughter” policies cannot be implemented or where wildlife reservoirs of Mycobacterium bovis infection serve as a recurrent source of ...
B. Buddle   +3 more
semanticscholar   +1 more source

BCG vaccine: a hope to control COVID-19 pandemic amid crisis

open access: yesHuman Vaccines & Immunotherapeutics, 2020
COVID-19 caused by the virus SARS-CoV-2 has gripped essentially all countries in the world, and has infected millions and killed hundreds of thousands of people. Several innovative approaches are in development to restrain the spread of SARS-CoV-2.
Y. Malik   +14 more
semanticscholar   +1 more source

NOD2/RIG-I Activating Inarigivir Adjuvant Enhances the Efficacy of BCG Vaccine Against Tuberculosis in Mice

open access: yesFrontiers in Immunology, 2020
Tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB) kills about 1.5 million people each year and the widely used Bacille Calmette-Guérin (BCG) vaccine provides a partial protection against TB in children and adults.
Arshad Khan   +12 more
semanticscholar   +1 more source

Research progress in the off-target effects of Bacille Calmette–Guérin vaccine

open access: yesChinese Medical Journal
. Bacille Calmette–Guérin (BCG) vaccine is designed to provide protection against tuberculosis (TB). However, numerous epidemiological, clinical, and immunological studies have shown that BCG vaccination affects neonatal and infant mortality, which may ...
Yanfei Wu   +7 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Bacille Calmette-Guérin Vaccine Strain Modulates the Ontogeny of Both Mycobacterial-Specific and Heterologous T Cell Immunity to Vaccination in Infants

open access: yesFrontiers in Immunology, 2019
Differences in Bacille Calmette-Guérin (BCG) immunogenicity and efficacy have been reported, but various strains of BCG are administered worldwide. Since BCG immunization may also provide protection against off-target antigens, we sought to identify the ...
Agano Kiravu   +17 more
doaj   +1 more source

Global shortages of BCG vaccine and tuberculous meningitis in children.

open access: yesLancet Global Health, 2019
CITATION: Du Preez, K., et al. 2019. Global shortages of BCG vaccine and tuberculous meningitis in children. Lancet Global Health, 7(1):e28-e29, doi:10.1016/S2214-109X(18)30474-1.
K. du Preez   +7 more
semanticscholar   +1 more source

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