Results 21 to 30 of about 420,990 (225)

A review of the tolerability of the candidate TB vaccine, MVA85A compared with BCG and Yellow Fever vaccines, and correlation between MVA85A vaccine reactogenicity and cellular immunogenicity [PDF]

, 2012
© 2012 Elsevier Ltd. All rights reservedBackground: The development of a new, more effective vaccine against tuberculosis (TB) for use in healthy and HIV-infected adults, children and infants, remains a global health priority.
Sander, C, Angela M Minassian, Nicola Williams, Lawrie, AM, Alison M Lawrie, Rowland, R, Poulton, ID, Rosalind Rowland, Brittain, N, Pathan, AA, David W Porter, Minassian, AM, Helen McShane, Iman Satti, Ansar A Pathan, Ian D Poulton, Nathaniel Brittain, Williams, N, Clare Sander, Porter, DW, Satti, I, McShane, H   +21 more
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Lack of immune responses to Mycobacterium tuberculosis DosR regulon proteins following Mycobacterium bovis BCG vaccination. [PDF]

, 2007
Mycobacterium bovis BCG is widely used as a vaccine against tuberculosis (TB), despite its variable protective efficacy. Relatively little is known about the immune response profiles following BCG vaccination in relation to protection against TB. Here we
Klein, Michèl R, Friggen, Annemieke H, Geluk, Annemieke, Lin, May Young, Verduyn, Marleen JC, Voskuil, Martin I, Huygen, Kris, Franken, Kees LMC, Smith, Steven G, van Meijgaarden, Krista E, Dockrell, Hazel M, Stewart, Amanda L, Ottenhoff, Tom HM   +12 more
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BCG Vaccines

Microbiology Spectrum, 2014
ABSTRACT BCG is the collective name for a family of live attenuated strains of Mycobacterium bovis that are currently used as the only vaccine against tuberculosis (TB). There are two major reasons for studying the genome of these organisms: (i) Because they are attenuated, BCG vaccines provide a window ...
Vanessa, Tran, Jun, Liu, Marcel A, Behr
openaire   +2 more sources

Evidence and guidance on vaccine safety and effectiveness in subpopulations [PDF]

, 2011
This dissertation examines post-licensing vaccine safety and effectiveness against two major respiratory diseases in specific subpopulations, with emphasis on safety.
Mak, Tippi
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Features of General Reactive Potential of the Body in Infants with BCG lymphadenitis

Aktualʹnaâ Infektologiâ, 2014
Objective: integrated health assessment of infants with BCG-induced regional lymphadenitis. Material and Methods. The work was carried out on the academic basis of pediatric infectious departments of Donetsk region and Donetsk regional laboratory center ...
A.I. Bobrovitskaia, T.F. Golubova, V.V. Suhodolskaia, L.A. Zakharova   +3 more
doaj   +1 more source

BCG vaccination strategies against tuberculosis: updates and perspectives

Human Vaccines & Immunotherapeutics, 2021
Bacillus Calmette-Guérin (BCG) is the only licensed vaccine against tuberculosis (TB). However, BCG has variable efficacy and cannot completely prevent TB infection and transmission.
Mengjin Qu, Xiangmei Zhou, Hao Li
doaj   +1 more source

Th1/Th17 cell induction and corresponding reduction in ATP consumption following vaccination with the novel Mycobacterium tuberculosis vaccine MVA85A. [PDF]

, 2011
Vaccination with Bacille Calmette-Guérin (BCG) has traditionally been used for protection against disease caused by the bacterium Mycobacterium tuberculosis (M.tb). The efficacy of BCG, especially against pulmonary tuberculosis (TB) is variable. The best
Minassian, Angela M, Pathan, Ansar A, Sander Clare R., Helen A. Fletcher, Fletcher, Helen A, Natalie E R Beveridge, Hill, AVS, Minassian Angela M., Angela M Minassian, Fletcher, HA, Kristin L. Griffiths, Pathan Ansar A., Kristin L Griffiths, Hill, Adrian VS, Griffiths Kristin L., Sander, CR, Hill Adrian V. S., McShane Helen, Beveridge Natalie E. R., Pathan, AA, Minassian, AM, Clare R. Sander, Ansar A. Pathan, Griffiths, KL, Beveridge, NER, Clare R Sander, Helen McShane, Ansar A Pathan, Natalie E. R. Beveridge, Griffiths, Kristin L, Sander, Clare R, Adrian V S Hill, Adrian V. S. Hill, Helen A Fletcher, Fletcher Helen A., Beveridge, Natalie ER, McShane, H, Angela M. Minassian, McShane, Helen   +38 more
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Boosting BCG with recombinant modified vaccinia ankara expressing antigen 85A: Different boosting intervals and implications for efficacy trials [PDF]

, 2007
Objectives. To investigate the safety and immunogenicity of boosting BCG with modified vaccinia Ankara expressing antigen 85A (MVA85A), shortly after BCG vaccination, and to compare this first with the immunogenicity of BCG vaccination alone and second
Whelan, KT, Pathan, Ansar A, Poulton Ian, Nicola C Alder, Sander Clare R., Whelan, Kathryn T, Kathryn T Whelan, Fletcher, Helen A, Natalie E R Beveridge, Hill, AVS, Alder, NC, Fletcher, HA, Pathan Ansar A., Hill, Adrian VS, Sander, CR, Hill Adrian V. S., McShane Helen, Beveridge Natalie E. R., Pathan, AA, Beveridge, NER, Alder, Nicola C, Clare R Sander, Helen McShane, Ansar A Pathan, Ian Poulton, Poulton, Ian, Alder Nicola C., Whelan Kathryn T., Poulton, I, Sander, Clare R, Adrian V S Hill, Helen A Fletcher, Fletcher Helen A., McShane, H, Beveridge, Natalie ER, McShane, Helen   +35 more
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The effect of birth weight and gestational age on BCG-induced immune responses in infants following BCG vaccination [PDF]

, 2010
Includes bibliographical references (leaves 102-114).Bacillus Calmette?Gu?rin (BCG), the only currently licensed tuberculosis (TB) vaccine, provides variable efficacy. Despite the use of BCG, TB remains a global health problem.
Dube, Frederick
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Reference genome and comparative genome analysis for the WHO reference strain for Mycobacterium bovis BCG Danish, the present tuberculosis vaccine

BMC Genomics, 2019
Background Mycobacterium bovis bacillus Calmette-Guérin (M. bovis BCG) is the only vaccine available against tuberculosis (TB). In an effort to standardize the vaccine production, three substrains, i.e.
Katlyn Borgers, Jheng-Yang Ou, Po-Xing Zheng, Petra Tiels, Annelies Van Hecke, Evelyn Plets, Gitte Michielsen, Nele Festjens, Nico Callewaert, Yao-Cheng Lin   +9 more
doaj   +1 more source