Evidence and guidance on vaccine safety and effectiveness in subpopulations [PDF]
This dissertation examines post-licensing vaccine safety and effectiveness against two major respiratory diseases in specific subpopulations, with emphasis on safety.
Mak, Tippi
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BCG vaccination induces different cytokine profiles following infant BCG vaccination in the UK and Malawi [PDF]
BACKGROUND: BCG vaccination of infants is thought to provide good protection in all settings. This study investigated whether Malawian infants made weaker responses across a cytokine panel after BCG vaccination, compared with UK infants.METHODS: Diluted ...
Hazel M. Dockrell +62 more
core +2 more sources
ABSTRACT BCG is the collective name for a family of live attenuated strains of Mycobacterium bovis that are currently used as the only vaccine against tuberculosis (TB). There are two major reasons for studying the genome of these organisms: (i) Because they are attenuated, BCG vaccines provide a window ...
Vanessa, Tran, Jun, Liu, Marcel A, Behr
openaire +2 more sources
Boosting BCG with recombinant modified vaccinia ankara expressing antigen 85A: Different boosting intervals and implications for efficacy trials [PDF]
Objectives. To investigate the safety and immunogenicity of boosting BCG with modified vaccinia Ankara expressing antigen 85A (MVA85A), shortly after BCG vaccination, and to compare this first with the immunogenicity of BCG vaccination alone and second
Whelan, KT +39 more
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Features of General Reactive Potential of the Body in Infants with BCG lymphadenitis
Objective: integrated health assessment of infants with BCG-induced regional lymphadenitis. Material and Methods. The work was carried out on the academic basis of pediatric infectious departments of Donetsk region and Donetsk regional laboratory center ...
A.I. Bobrovitskaia +3 more
doaj +1 more source
BCG vaccination strategies against tuberculosis: updates and perspectives
Bacillus Calmette-Guérin (BCG) is the only licensed vaccine against tuberculosis (TB). However, BCG has variable efficacy and cannot completely prevent TB infection and transmission.
Mengjin Qu, Xiangmei Zhou, Hao Li
doaj +1 more source
BCG vaccine reactivation after mRNA immunization against COVID-19: case report
The Bacillus Calmette-Guérin (BCG) vaccine is a live attenuated pathogen vaccine used to prevent severe types of tuberculosis. A related immunological event is its scar reactivation.
José Paulo Ribeiro Júnior +3 more
doaj +1 more source
Th1/Th17 cell induction and corresponding reduction in ATP consumption following vaccination with the novel Mycobacterium tuberculosis vaccine MVA85A. [PDF]
Vaccination with Bacille Calmette-Guérin (BCG) has traditionally been used for protection against disease caused by the bacterium Mycobacterium tuberculosis (M.tb). The efficacy of BCG, especially against pulmonary tuberculosis (TB) is variable. The best
Minassian, Angela M +43 more
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Polyantigenic Interferon-γ Responses are Associated with Protection from TB Among HIV-Infected Adults with Childhood BCG Immunization. [PDF]
Surrogate immunologic markers for natural and vaccine-mediated protection against tuberculosis (TB) have not been identified. HIV-infected adults with childhood BCG immunization entering the placebo arm of the DarDar TB vaccine trial in Dar es Salaam ...
Horsburgh, C Robert +42 more
core +1 more source
Background Mycobacterium bovis bacillus Calmette-Guérin (M. bovis BCG) is the only vaccine available against tuberculosis (TB). In an effort to standardize the vaccine production, three substrains, i.e.
Katlyn Borgers +9 more
doaj +1 more source

