Results 21 to 30 of about 57,515 (295)

Complete Genome Sequence, Genome Stability and Phylogeny of the Vaccine Strain Mycobacterium bovis BCG SL222 Sofia

Vaccines, 2021
Mycobacterium bovis bacillus Calmette–Guérin (BCG) is the only live attenuated vaccine available against tuberculosis. The first BCG vaccination was done exactly 100 years ago, in 1921.
Stefan Panaiotov, Yordan Hodzhev, Vladimir Tolchkov, Borislava Tsafarova, Alexander Mihailov, Tzvetelina Stefanova   +5 more
doaj   +1 more source

Sleeping Beauty and the Story of the Bacille Calmette-Guérin Vaccine

mBio, 2016
Mycobacterium bovis BCG is the only available vaccine for protection against tuberculosis (TB). While BCG protects children from severe disease, it has little impact on pulmonary disease in adults. A recombinant BCG vaccine BCG ΔureC::hly (strain VPM1002)
Helen A. Fletcher
doaj   +1 more source

BCG vaccine reactivation after mRNA immunization against COVID-19: case report

Revista Médica de Minas Gerais, 2023
The Bacillus Calmette-Guérin (BCG) vaccine is a live attenuated pathogen vaccine used to prevent severe types of tuberculosis. A related immunological event is its scar reactivation.
José Paulo Ribeiro Júnior, Maria do Carmo Araújo Palmeira Queiroz, Arnoud de Lucena Flor, Clause Willdys Medeiros Dantas   +3 more
doaj   +1 more source

BCG vaccination strategies against tuberculosis: updates and perspectives

Human Vaccines & Immunotherapeutics, 2021
Bacillus Calmette-Guérin (BCG) is the only licensed vaccine against tuberculosis (TB). However, BCG has variable efficacy and cannot completely prevent TB infection and transmission.
Mengjin Qu, Xiangmei Zhou, Hao Li
doaj   +1 more source

Evolution of the Bacillus Calmette-Guérin scar Russia and Moreau strains in newborns: A brazilian cohort

Vaccine: X, 2023
Background: In Brazil, in 1925, the Moreau strain was introduced, and since its implementation, it has been the routine vaccine for health services. Since 2013, many countries, including Brazil, have been experiencing problems with the production of ...
Ramon Andrade de Souza, Florisneide Rodrigues Barreto, Carlos Antônio de Souza Teles Santos, Joilda Silva Nery, Carla Cristina Oliveira de Jesus Lima, Isabella Soares Castelo, Marcio Natividade, Jacy Amaral Freire de Andrade, Maurício Lima Barreto, Susan Martins Pereira   +9 more
doaj   +1 more source

A systematic review of the impact of psychosocial factors on immunity: Implications for enhancing BCG response against tuberculosis. [PDF]

, 2019
Background: Tuberculosis (TB) remains an urgent global public health priority, causing 1.5 million deaths worldwide in 2018. There is evidence that psychosocial factors modulate immune function; however, how this may influence TB risk or BCG vaccine ...
Boccia, D, Dowd, JB, Fletcher, H, Hayward, SE, Nellums, LB, Wurie, F   +5 more
core   +2 more sources

Time to face the proofs: the BCG Moreau vaccine promotes superior inflammatory cytokine profile in vitro when compared with Russia, Pasteur, and Danish strains

Human Vaccines & Immunotherapeutics, 2022
Tuberculosis (TB) has been a major public health problem worldwide, and the Bacillus Calmette–Guérin (BCG) vaccine is the only available vaccine against this disease. The BCG vaccine is no longer a single organism; it consists of diverse strains.
Andreon Santos Machado da Silva, Lawrence Henrique Paz Albuquerque, Carlos Germano Garrido de Ponte, Matheus Rogério de Almeida, Sandra Elizabete Ribeiro de Faria, Mariana da Silva Ribeiro, Evelyn Nunes Goulart da Silva Pereira, Paulo Renato Zuquim Antas   +7 more
doaj   +1 more source

Persistence of the immune response induced by BCG vaccination. [PDF]

, 2008
BACKGROUND: Although BCG vaccination is recommended in most countries of the world, little is known of the persistence of BCG-induced immune responses. As novel TB vaccines may be given to boost the immunity induced by neonatal BCG vaccination, evidence ...
Anne Ben-Smith, AR Bennett, B Combadiere, CE Palmer, Department of Health, Department of Health, GA Colditz, GF Black, GF Black, H Igari, H McShane, Hazel M Dockrell, I Sutherland, JA Sterne, Karonga Prevention Trial Group, Keith Branson, L Brandt, Maeve K Lalor, ML Barreto, NE Aronson, P Andersen, P Gorak-Stolinska, Patricia Gorak-Stolinska, Paul EM Fine, RE Weir, RE Weir, Rose Blitz, Rosemary E Weir, S Floyd, Sally Stenson, Sian Floyd   +30 more
core   +3 more sources

Features of General Reactive Potential of the Body in Infants with BCG lymphadenitis

Aktualʹnaâ Infektologiâ, 2014
Objective: integrated health assessment of infants with BCG-induced regional lymphadenitis. Material and Methods. The work was carried out on the academic basis of pediatric infectious departments of Donetsk region and Donetsk regional laboratory center ...
A.I. Bobrovitskaia, T.F. Golubova, V.V. Suhodolskaia, L.A. Zakharova   +3 more
doaj   +1 more source

Listeria-Vectored Multiantigenic Tuberculosis Vaccine Enhances Protective Immunity against Aerosol Challenge with Virulent Mycobacterium tuberculosis in BCG-Immunized C57BL/6 and BALB/c Mice

mBio, 2022
Mycobacterium tuberculosis infects approximately one-third of the world's population, causing active tuberculosis (TB) in ~10 million people and death in ~1.5 million people annually. A potent vaccine is needed to boost the level of immunity conferred by
Qingmei Jia, Saša Masleša-Galić, Susana Nava, Marcus A. Horwitz   +3 more
doaj   +1 more source