Results 81 to 90 of about 58,969 (272)
Journal of Internal Medicine, Volume 299, Issue 3, Page 328-348, March 2026.Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron +3 more
wiley +1 more source
Vaccines, 2013 Early attempts to improve BCG have focused on increasing the expression of prominent antigens and adding recombinant toxins or cytokines to influence antigen presentation.
Douglas S. Kernodle +8 more
doaj +1 more source
Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy
Cancer Medicine, Volume 15, Issue 2, February 2026.ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li +13 more
wiley +1 more source
Frontiers in Immunology, 2014 BCG (Bacille Calmette-Guérin), an attenuated vaccine derived from Mycobacterium bovis, is the current vaccine of choice against tuberculosis (TB). Despite its protection against active TB in children, BCG has failed to protect adults against TB infection
Adeliane C da Costa +3 more
doaj +1 more source
Pulmonary Tuberculosis: The Great Mimicker of Lung Cancer
Clinical Case Reports, Volume 14, Issue 2, February 2026.Computed tomography (CT) scan of the chest with contrast indicating a soft tissue density in the left upper lobe. ABSTRACT Though tuberculosis (TB) is an ancient pathogen, diagnosis remains challenging. Distinguishing pulmonary tuberculoma, a rare manifestation of TB, from lung cancer is critical.
Laura Corrales‐Diaz Pomatto‐Watson +2 more
wiley +1 more source
KAP Study on Immunization of Children in a City of North India – A 30 Cluster Survey [PDF]
, 2008 Background: To determine the knowledge, attitude and practices about immunization among respondents of children aged 12-23 months.\ud Methods: A total of 510 respondents were interviewed in the urban slums of Lucknow district of India, using 30 cluster ...
Awasthi, Shally +5 more
core
Tuberculosis vaccine: pipeline approaches and future prospective [PDF]
, 2011 Tuberculosis (TB), despite anti-mycobacterial therapies and vaccine, is a deadly infectious disease with about 12 million incident cases worldwide. Existing Bacillus Calmette-Guérin (BCG) vaccine is unquestionably inexpensive, safe and effective ...
Ankita Singh +2 more
core +2 more sources
Chronic Granulomatous Disease: Clinical and Molecular Characterization of Brazilian Patients
The Journal of Gene Medicine, Volume 28, Issue 2, February 2026.Chronic granulomatous disease is a rare inborn error of immunity characterized by the deficient production of reactive oxygen species in phagocytes, which are used in pathogen elimination. Affected individuals become susceptible to severe infections.
Leonardo Martinello da Rosa +4 more
wiley +1 more source
BMC MicrobiologyBackground The Bacille Calmette-Guérin (BCG) vaccine, developed in the early 20th century, remains the only widely approved prophylactic against tuberculosis (TB). It was derived from an attenuated strain of Mycobacterium bovis.
Paloma Rezende Corrêa +4 more
doaj +1 more source
Revista de Saúde Pública, 2007 OBJETIVO: A vacina BCG é utilizada desde 1921, embora ainda apresente controvérsias e aspectos não esclarecidos. O objetivo do artigo foi analisar aspectos relacionados ao efeito protetor da primeira e segunda doses da vacina BCG e as políticas de ...
Susan M Pereira +3 more
doaj +1 more source