Results 221 to 230 of about 369,993 (297)

Dephosphorylation Targets Bcl-2 for Ubiquitin-dependent Degradation: A Link between the Apoptosome and the Proteasome Pathway [PDF]

, 1999
Stefanie Dimmeler, Kristin Breitschopf, Judith Haendeler, Andreas M. Zeiher   +3 more
openalex   +1 more source

Sacubitril/valsartan preserves regional cardiac function following myocardial infarction in rats

ESC Heart Failure, Volume 12, Issue 2, Page 1304-1315, April 2025.
Parts of the figure were drawn by using pictures from Servier Medical Art. Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by/3.0/). Abstract Aims Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction
Einar Sjaastad Nordén, Bård Andre Bendiksen, Kaja Knudsen Bergo, Emil Knut Stenersen Espe, Gary McGinley, Almira Hasic, Ida Marie Hauge‐Iversen, Hege Katrin Ugland, Xin Shen, Michael Frisk, Nishani S. Mabotuwana, William E. Louch, Rizwan I. Hussain, Lili Zhang, Ivar Sjaastad, Alessandro Cataliotti, Geir Christensen   +16 more
wiley   +1 more source

Oral Combined Probiotics Clostridium butyricum and Akkermansia muciniphila Inhibits the Progression of 4T1 Breast Cancer by Activating Bcl-2/Bax Pathway. [PDF]

Cancer Med
Li X, Hua D, Wu D, Hong W, Kang Y, Tang L, Yang Q, Wang X, Li B, Li R, Chen Z, Cui G.   +11 more
europepmc   +1 more source

Targeted reactivation of the novel tumor suppressor DAPK1, an upstream regulator of p53, in high‐grade serous ovarian cancer by mRNA liposomes reduces viability and enhances drug sensitivity in preclinical models

Cancer Communications, EarlyView.
Monika Raab, Balázs Győrffy, Samuel Peña‐Llopis, Daniela Fietz, Monika Kressin, Margareta Kolaric, Matthias Ebert, Khayal Gasimli, Sven Becker, Mourad Sanhaji, Klaus Strebhardt   +10 more
wiley   +1 more source

Mitochondria‐Nuclear Crosstalk: Orchestrating mtDNA Maintenance

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The mitochondria (mt) and nucleus engage in a dynamic bidirectional communication to maintain cellular homeostasis, regulating energy production, stress response, and cell fate. Anterograde signaling directs mt function, while retrograde signaling conveys metabolic and stress‐related changes from mt to the nucleus. Central to this crosstalk is
Ghazal Darfarin, Janice Pluth
wiley   +1 more source

BCL-2 inhibitors in hematological malignancies: biomarkers that predict response and management strategies. [PDF]

Front Oncol
Markouli M, Pagoni MN, Diamantopoulos P.
europepmc   +1 more source

The Chicken Egg Genotoxicity Assay (CEGA): Assessing Target Tissue Exposure and Metabolism in the Embryo‐Fetal Chicken Livers

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The Chicken Egg Genotoxicity Assay (CEGA) is an avian egg‐based model that utilizes the livers of developing chicken embryo‐fetuses to assess the ability of chemicals to produce direct DNA damage. The main goal of the study was to evaluate target tissue exposure and metabolism in the CEGA to assess its suitability as a biologically relevant ...
Yax Thakkar, T. Kobets, Anne Marie Api, J. D. Duan, G. M. Williams   +4 more
wiley   +1 more source

Bcl-2 and Bcl-xL in Diabetes: Contributions to Endocrine Pancreas Viability and Function. [PDF]

Biomedicines
Perez-Serna AA, Guzman-Llorens D, Dos Santos RS, Marroqui L.   +3 more
europepmc   +1 more source

Cell proliferation, cell loss and expression of bcl-2 and p53 in human pulmonary neoplasms

, 1997
M. Kennedy, D Lamb, George King, K.M. Kerr   +3 more
openalex   +2 more sources

Cumulative prognostic value ofp53 mutations and bcl-2 protein expression in head-and-neck cancer treated by radiotherapy [PDF]

, 1999
Oreste Gallo, Ilaria Chiarelli, Vieri Boddi, Corso Bocciolini, Luca Bruschini, Berardino Porfirio   +5 more
openalex   +1 more source