Results 141 to 150 of about 59,389 (246)
Anticancer Molecular Mechanisms of Phytosterols: An Updated Review on Clinical Trials
Phytosterols, a form of naturally occurring substance structurally related to cholesterol, have been getting considerable interest due to their possible anticancer properties. Phytosterols induce apoptosis, block the cell cycle, and abrogate the invasion and metastasis of cancer cells, offering a multi‐manifestation treatment of cancer.
Muhammad Shahbaz +14 more
wiley +1 more source
c-Myb Promotes the Survival of CD4+CD8+ Double-Positive Thymocytes through Upregulation of Bcl-xL
Joan Yuan +2 more
openalex +2 more sources
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) is a malignancy with poor prognosis and survival. While epidermal growth factor receptor (EGFR) is a known driver of HNSCC, EGFR inhibitors show limited efficacy as monotherapies, suggesting that effective combination therapies are needed.
Jiayu Wang +13 more
wiley +1 more source
Quiescent memory B cells in human peripheral blood co-express bcl-2 and bcl-xL anti-apoptotic proteins at high levels [PDF]
Fabrice Bovia +5 more
openalex +1 more source
New cell lines expanding the diversity of Ewing sarcoma models
What's new? A chromosomal translocation between the EWSR1 and ETS genes is the key oncogenic driver in Ewing sarcoma. EWSR1::FLI1, the most frequent fusion, is subdivided into different fusion types with unclear prognostic relevance. Here, the authors describe the establishment and characterization of four new, intrinsically immortal, patient‐derived ...
Maximilian Kerkhoff +13 more
wiley +1 more source
148 EPIDERMAL GROWTH FACTOR INDUCES BCL-XL GENE EXPRESSION AND REDUCES APOPTOSIS IN PORCINE PARTHENOTES DEVELOPING IN VITRO [PDF]
Xiaopeng Cui +3 more
openalex +1 more source
Crystal Structure of Rat Bcl-xL [PDF]
Masaharu Aritomi +5 more
openaire +1 more source
Early low‐dose IL‐2 administration after haploidentical HSCT promotes the reconstitution of NK cells and regulatory T cells (Tregs), enhances their activation (CD122+, DNAM‐1+, NKG2D+, CD62L+), and increases plasma cytokines (IFN‐γ, TNF‐α, IL‐10, IL‐2).
Zheng‐Li Xu +13 more
wiley +1 more source
Paeonol Inhibits Cell Growth by Inducing Ferroptosis in Human Glioma Cells
ABSTRACT Paeonol (PAE), a phenolic phytochemical derived from traditional Chinese medicinal plants, exhibits multifaceted pharmacological properties including demonstrated antitumor efficacy against hepatic, gastric, and breast carcinomas. However, its therapeutic potential in glioma remains unexplored.
Xin Li +8 more
wiley +1 more source

