Results 191 to 200 of about 45,247 (265)
Summary Dendrobium devonianum, a species of the Orchidaceae family, is notable for its unique floral characteristics, which include two yellow spots and purple tips on its labellum, as well as fringed edges. However, the molecular mechanisms underlying flower pattern formation in D.
Jing Wang+10 more
wiley +1 more source
Activated ras Prevents Downregulation of Bcl-XL Triggered by Detachment from the Extracellular Matrix [PDF]
Kirill V. Rosen+5 more
openalex +1 more source
ABSTRACT Objective To determine if superficial corneal ulcers related to corneal endothelial degeneration (CED) or other concurrent ophthalmic disease (COD) had significantly different healing outcomes and incidences of complications post‐diamond burr debridement (DBD) compared to spontaneous chronic corneal epithelial defects (SCCEDs) undergoing DBD ...
Samantha Dacanay‐DeFebo+4 more
wiley +1 more source
Epigenetic Determinants of Resistance to Etoposide Regulation of Bcl-xL and Bax by Tumor Microenvironmental Factors [PDF]
Sian Taylor+2 more
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14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley +1 more source
Bcl-xL promotes metastasis of breast cancer cells by induction of cytokines resistance [PDF]
Yolanda Fernández+4 more
openalex +1 more source
TP53‐Mutated Acute Myeloid Leukemia: Unanswered Questions
ABSTRACT TP53‐mutated acute myeloid leukemia (AML) remains one of the most treatment‐resistant hematologic malignancies, with poor overall survival despite advancements in therapeutic strategies. The loss of functional p53 compromises DNA repair, apoptosis, and genomic stability, rendering both conventional and novel therapies largely ineffective. This
Antonella Bruzzese+11 more
wiley +1 more source
THE INTRAGRAFT GENE EXPRESSION OF BCL-XL AND BAX COULD PREDICT THE OUTCOME OF THE KIDNEY ALLOGRAFT.
D-W Chae+9 more
openalex +1 more source
ABSTRACT Background Venetoclax is a potent, oral BCL‐2 inhibitor approved as combination therapy for the treatment of adults with newly diagnosed acute myeloid leukaemia (AML) who are ineligible for intensive chemotherapy. This study evaluated the safety and preliminary efficacy of venetoclax alone or combined with chemotherapy in paediatric and ...
Seth E. Karol+29 more
wiley +1 more source