Bcl-xL overexpression in T cells preserves muscle mitochondrial structure and function and prevents frailty in old mice. [PDF]
Mas-Bargues C +8 more
europepmc +1 more source
A novel regimen for pancreatic ductal adenocarcinoma targeting MEK, BCL-xL, and EGFR. [PDF]
Han S +10 more
europepmc +1 more source
Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis. [PDF]
Zhang T +19 more
europepmc +1 more source
Efficacy of a novel BCL-xL degrader, DT2216, in preclinical models of JAK2-mutated post-MPN AML.
Wang Z +23 more
europepmc +1 more source
Discovery of PZ671, a highly potent and <i>in vivo</i> active CRBN-recruiting Bcl-xL degrader. [PDF]
Zhang P +9 more
europepmc +1 more source
Tumorigenicity decrease in Bcl-xL deficient MDCK cells ensuring the safety for influenza vaccine production. [PDF]
Zheng J +11 more
europepmc +1 more source
Targeted Penetrating Motif Engineering of BH3 Mimetic: Harnessing Non-Canonical Amino Acids for Coinhibition of MCL-1 and BCL-xL in Acute Myeloid Leukemia. [PDF]
Wang Z +11 more
europepmc +1 more source
A combination of Dihydroartemisinin and Venetoclax enhances antitumor effect in AML via C-MYC/BCL-XL/MCL-1 triple targeting. [PDF]
Li F +9 more
europepmc +1 more source
A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice. [PDF]
Yang Y +15 more
europepmc +1 more source
WWOX Induction Promotes Bcl-X<sub>L</sub> and Mcl-1 Degradation Through a Lysosomal Pathway upon Stress Responses. [PDF]
Su YH +8 more
europepmc +1 more source

