Results 221 to 230 of about 45,247 (265)

Bcl-xL Blocks Transforming Growth Factor-β1-induced Apoptosis by Inhibiting Cytochrome c Release and Not by Directly Antagonizing Apaf-1-dependent Caspase Activation in Prostate Epithelial Cells [PDF]

, 2001
Jerry E. Chipuk, Manjunatha B. Bhat, Andrew Y. Hsing, Jianjie Ma, David Danielpour   +4 more
openalex   +1 more source

Emerging Links Between Ferroptosis and Neurodegeneration: Implications for Disease Mechanisms and Nutraceutical Interventions

Food Science &Nutrition, Volume 13, Issue 6, June 2025.
Ferroptosis, a controlled cell death, is driven by iron and characterized by reactive oxygen species and lipid peroxidation. The impact of lipid peroxides, GSH/GPX4, and iron metabolism–targeting small molecule inhibitors is discussed. Nucleic acids, proteins, and phytochemicals are implicated as inhibitors of ferroptosis.
Anwar Ali, Quratulain Babar, Ayesha Saeed, Domenico Sergi, Nenad Naumovski, Isam A. Mohamed Ahmed, Ghalia Shamlan, Halah Abdulrahman Hafiz, Muhammad Faisal Manzoor, Joanna Trafialek, Felix Kwashie Madilo   +10 more
wiley   +1 more source

Contribution of Bcl-2, but Not Bcl-xL and Bax, to Antiapoptotic Actions of Hepatocyte Growth Factor in Hypoxia-Conditioned Human Endothelial Cells [PDF]

, 2001
Kei Yamamoto, Ryuichi Morishita, Shinichiro Hayashi, Hidetsugu Matsushita, Hironori Nakagami, Atsushi Moriguchi, Kunio Matsumoto, Toshikazu Nakamura, Yasufumi Kaneda, Toshio Ogihara   +9 more
openalex   +1 more source

Prolongation of murine hybridoma cell survival in stationary batch culture by Bcl-xL expression.

, 2000
Joel R. Charbonneau, Eric R. Gauthier
openalex   +2 more sources

Bcl-xL Expression Correlates with Primary Macrophage Differentiation, Activation of Functional Competence, and Survival and Results from Synergistic Transcriptional Activation by Ets2 and PU.1 [PDF]

, 2001
Lídia Sevilla, Arnaud Zaldumbide, Françoise Carlotti, Manal Abdel Dayem, Philippe Pognonec, Kim E. Boulukos   +5 more
openalex   +1 more source

Inhibition of LPS-induced Cytokines by Bcl-xL in a Murine Macrophage Cell Line

, 2000
Viktor Lakics, Andrei E. Medvedev, Seiji Okada, Stefanie N. Vogel   +3 more
openalex   +1 more source

Geranylgeraniol, an Intermediate Product in Mevalonate Pathway, Induces Apoptotic Cell Death in Human Hepatoma Cells: Death Receptor‐independent Activation of Caspase‐8 with Down‐regulation of Bcl‐xL Expression [PDF]

, 2001
Yoshio Takeda, Kazuhiko Nakao, Keisuke Nakata, Atsushi Kawakami, Hiroaki Ida, Tatsuki Ichikawa, Masaya Shigeno, Yuji Kajiya, Keisuke Hamasaki, Yuji Kato, Katsumi Eguchi   +10 more
openalex   +1 more source

Pleiotropic Effects of Metformin on the Chemotherapy Response of HPV‐Positive Cancer Cells

Journal of Medical Virology, Volume 97, Issue 6, June 2025.
ABSTRACT Improved treatment strategies for HPV‐positive cancers are urgently required. The viral E6/E7 oncoproteins are essential for the proliferation of HPV‐positive cancer cells and considered attractive therapeutic targets. Metformin is proposed to be repurposed for cancer therapy, but this is under controversial debate.
Alicia Avenhaus, Bianca J. Kuhn, Milica Velimirović, Tobias D. Strobel, Julia Bulkescher, Claudia Lohrey, Jeroen Krijgsveld, Felix Hoppe‐Seyler, Karin Hoppe‐Seyler   +8 more
wiley   +1 more source

Akt and Bcl-xL Promote Growth Factor-independent Survival through Distinct Effects on Mitochondrial Physiology [PDF]

, 2001
David R. Plas, Sunit Talapatra, Aimee L. Edinger, Jeffrey C. Rathmell, Craig B. Thompson   +4 more
openalex   +1 more source

Ferulic acid: extraction, estimation, bioactivity and applications for human health and food

Journal of the Science of Food and Agriculture, Volume 105, Issue 8, Page 4168-4177, June 2025.
Abstract Ferulic acid ((E)‐3‐(4‐hydroxy‐3‐methoxy‐phenyl) prop‐2‐enoic acid) is a derivative of caffeic acid found in most plants. This abundant phenolic compound exhibits significant antioxidant capacity and a broad spectrum of therapeutic effects, including anti‐inflammatory, antimicrobial, anticancer, antidiabetic, cardiovascular and neuroprotective
Mukul Kumar, Deepika Kaushik, Shubham Shubham, Ashwani Kumar, Vishal Kumar, Emel Oz, Charles Brennan, Maomao Zeng, Charalampos Proestos, Kenan Çadırcı, Muharrem Bayrak, Tahra Elobeid, Sercan Karav, Fatih Oz   +13 more
wiley   +1 more source