Results 71 to 80 of about 109,902 (263)

Late Pleistocene Volcanic Rocks From Tengchong Volcanic Field at SE Tibetan Plateau: Constraints on Petrogenesis and Mantle and Crustal Processes

Geological Journal, EarlyView.
Early zircon saturation and crystallisation occur in mafic (52–54 wt.% SiO2) lavas at Tengchong volcanic field. These early formed zircons with high δ18O (6.6‰–7.9‰) indicates mantle enrichment by subducted supracrustal materials. ABSTRACT Late Pleistocene (< 0.2 Ma) mafic and evolved volcanic rocks occur in northern Tengchong Volcanic Field, SE ...
Lizhu Wang, Haibo Zou
wiley   +1 more source

High-Level Expression, Purification and Characterization of A Recombinant Plasmodium vivax Apical Membrane Antigen 1: Implication for vivax Malaria Vaccine Development

Cell Journal, 2015
Objective: The apical membrane antigen-1 (AMA-1) is considered as a promising candidate for development of a malaria vaccine against Plasmodium parasites.
Maryam Salavatifar, Sedigheh Zakeri, Nasim Hayati Roodbari, Navid Dinparast Djadid   +3 more
doaj  

A Reassessment of Petrochemistry of ~1.2 Ga Tonalitic Rocks of the Northern Tugela Terrane, Natal Metamorphic Belt, South Africa: Further Constraints on the Evolution of This Belt

Geological Journal, EarlyView.
Our petrochemical studies on ~1.2 Ga granitoids of the Natal Metamorphic Belt, South Africa, do not suggest any property similar to Phanerozoic‐style subduction‐related granitoids. Plot of Kotongweni Tonalite in Y versus Sr diagram (after Moyen 2011), note that most samples have Sr/Y < 50.
Palesa Leuta, Saumitra Misra, Thembiso O. Basupi   +2 more
wiley   +1 more source

The Impact of Market Liberalisation on Bank Performance: Evidence From South and Southeast Asian Countries

International Journal of Finance &Economics, EarlyView.
ABSTRACT Utilising annual data covering 1995–2022, this study examines the effects of market liberalisation on bank performance in 19 South and Southeast Asian countries. Bank performance is assessed using three dimensions: efficiency, profitability, and stability.
Michael Enowbi Batuo, Sridevi Yerrabati, Ashiq Zaman, Helen Solomon   +3 more
wiley   +1 more source

Single‐cell profiling of peripheral blood reveals acute‐phase immune dysregulation in human scrub typhus

iMeta, EarlyView.
Integrated single‐cell RNA sequencing, spectral flow cytometry, immune‐receptor repertoire profiling, and plasma proteomics revealed coordinated peripheral immune remodeling during acute scrub typhus. Patients exhibited expansion of cytotoxic, clonally amplified CD8+ T cells with exhaustion‐associated features, depletion and apoptosis of CD4+ T cells ...
Yijia Guo, Yi Niu, Nihui Zhang, Xiao Han, Liyuan Zhang, Yongguo Du, Lifen Han, Xiuying Tian, Zhao Xu, Gaoyu Wang, Kwok‐Yung Yuen, Jasper Fuk‐Woo Chan, Dahua Xu, Feifei Yin   +13 more
wiley   +1 more source

BCR-ABL1 genomic DNA PCR response kinetics during first-line imatinib treatment of chronic myeloid leukemia

Haematologica, 2018
Accurate quantification of minimal residual disease (MRD) during treatment of chronic myeloid leukemia (CML) guides clinical decisions. The conventional MRD method, RQ-PCR for BCR-ABL1 mRNA, reflects a composite of the number of circulating leukemic ...
Ilaria S. Pagani, Phuong Dang, Ivar O. Kommers, Jarrad M. Goyne, Mario Nicola, Verity A. Saunders, Jodi Braley, Deborah L. White, David T. Yeung, Susan Branford, Timothy P. Hughes, David M. Ross   +11 more
doaj   +1 more source

Suppression of autophagy by BCR ABL

Frontiers in Bioscience, 2012
Imatinib and second generation BCR/ABL tyrosine kinase inhibitors (TKIs) serve now as standard therapies for patients with chronic myelogenous leukemia (CML); however, CML stem cells are intrinsically insensitive to the cell death-inducing effects of TKIs, allowing the persistence of a "reservoir" of BCR/ABL-expressing CML-initiating cells potentially ...
CALABRETTA, Bruno, SALOMONI, Paolo
openaire   +4 more sources

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Metabolic feature profiling and metabolic vulnerability in acute lymphoblastic leukemia

Interdisciplinary Medicine, EarlyView.
For the first time, our study develops a novel metabolic classification and subtyping program, metabolic reprogramming‐based classifier for acute lymphoblastic leukemia, using internal PDT‐ALL‐2016 and external cohorts, which dissects metabolic profiling, clinical outcome, and therapeutic vulnerability for precision metabolic intervention in ALL ...
Xiaojie Liang, Zihong Cai, Bingqing Tang, Zicong Huang, Baiwei Luo, Bingyu Lin, Yunong Yang, Zhihao Jin, Xiaoqing Li, Xiuli Xu, Yeling Deng, Chaoran Lin, Liang Wang, Hongsheng Zhou   +13 more
wiley   +1 more source

An In-house Method for Molecular Monitoring of BCR-ABL

Turkish Journal of Hematology, 2012
OBJECTIVE: At present in Turkey, centers that are able to give reliable RQ-PCR BCR-ABL results are limited in number. We aimed to describe a cost-effective, in-house method for BCR-ABL quantification and to illustrate an example for RQ-PCR validation ...
Hakkı Ogun Sercan, Ilgın Öztürk, Ceyda Çalışkan, Melek Pehlivan, Zeynep Sercan   +4 more
doaj   +1 more source