Results 81 to 90 of about 288,388 (279)
A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application
Advanced Science, EarlyView.This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu +5 more
wiley +1 more source
CellsStem cell-based therapies hold significant potential for cancer treatment due to their unique properties, including migration toward tumor niche, secretion of bioactive molecules, and immunosuppression.
Yasser Basmaeil +5 more
doaj +1 more source
Activation of tyrosine kinases by mutation of the gatekeeper threonine. [PDF]
, 2008 Protein kinases targeted by small-molecule inhibitors develop resistance through mutation of the gatekeeper threonine residue of the active site. Here we show that the gatekeeper mutation in the cellular forms of c-ABL, c-SRC, platelet-derived growth ...
Azam, Mohammad +4 more
core +1 more source
A Scalable Framework for Comprehensive Typing of Polymorphic Immune Genes from Long‐Read Data
Advanced Science, EarlyView.SpecImmune introduces a unified computational framework optimized for long‐read sequencing to resolve over 400 highly polymorphic immune genes. This scalable approach achieves high‐resolution typing, enabling the discovery of cross‐family co‐evolutionary networks and population‐specific diversity.
Shuai Wang +5 more
wiley +1 more source
Jurnal Penyakit Dalam Indonesia, 2018 Introduction. Patients with chronic phase Chronic Myeloid Leukemia (CML) at Hematology-Medical Oncology Clinic Department of Internal Medicine dr. Cipto Mangunkusumo National Hospital who haveperformed cytogenetic and RTPCR BCR-ABL examination showed: Ph
Wulyo Rajabto +3 more
doaj +1 more source
Genetic requirement for Ras in the transformation of fibroblasts and hematopoietic cells by the Bcr-Abl oncogene. [PDF]
, 1995 To determine the functional importance of Ras in transformation by Abl oncogenes, we used a genetic approach to measure the effect of impaired Ras activity on the ability of Bcr-Abl or v-Abl to transform cells.
McLaughlin, J, Sawyers, CL, Witte, ON
core
Advanced Science, EarlyView.A lithium‐bearing slag is investigated with the goal of holistic valorization. The present β‐eucryptite (LiAlSiO4) exhibits a high lithium content and low levels of impurities. The spinel contains most of the chromium and vanadium, representing additional valorization opportunities.
Peter Cornelius Gantz +9 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Age of symptom onset is highly variable in familial frontotemporal lobar degeneration (f‐FTLD). Accurate prediction of onset would inform clinical management and trial enrollment. Prior studies indicate that individualized maps of brain atrophy can predict conversion to dementia in f‐FTLD.
Shubir Dutt +82 more
wiley +1 more source
Influence of statin use on clinicopathological characteristics of localized prostate cancer and outcomes obtained after radical prostatectomy: a single center study [PDF]
, 2015 To assess the impact of statin use on biochemical recurrence (BCR) of prostate cancer after radical prostatectomy (RP)
Cattarino, Susanna +8 more
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Colouring inside what lines?: interference of the urban growth boundary and the political-administrative border of Brussels [PDF]
, 2013 This paper discusses the relationship between the political-administrative border and the urban growth boundary around Brussels, the Belgian capital. Our hypothesis is that the interests of the various regions and language groups in Belgium interfere ...
Allaert, Georges +2 more
core +1 more source