Results 31 to 40 of about 220,963 (383)
Target-derived neurotrophic factors regulate the death of developing forebrain neurons after a change in their trophic requirements [PDF]
, 2001 Many neurons die as the normal brain develops. How this is regulated and whether the mechanism involves neurotrophic molecules from target cells are unknown.
Asavaritikrai, P +3 more
core +1 more source
Tristetraprolin is a novel regulator of BDNF [PDF]
SpringerPlus, 2014 AbstractBrain-derived neurotrophic factor (BDNF) regulates multiple biological processes ranging from central nervous system development and function to neuroinflammation and myogenic differentiation and repair. While coordination of BDNF levels is central in determining the biological outcome, mechanisms involved in controlling BDNF levels are not ...
Kumar, Anmol +3 more
openaire +4 more sources
Science, 2018 Adult neurogenesis and Alzheimer's disease Alzheimer's disease (AD) pathology destroys neurons and synapses in the brain, leading to dementia. The brain generates new neurons throughout life in the hippocampus, a process called adult hippocampal ...
Se Hoon Choi +19 more
semanticscholar +1 more source
Journal of Neuroscience, 2020 BDNF signaling via its transmembrane receptor TrkB has an important role in neuronal survival, differentiation, and synaptic plasticity. Remarkably, BDNF is capable of modulating its own expression levels in neurons, forming a transcriptional positive ...
Eli-Eelika Esvald +5 more
semanticscholar +1 more source
Activation of adenosine A2A receptors induces TrkB translocation and increases BDNF-mediated phospho-TrkB localization in lipid rafts : implications for neuromodulation [PDF]
, 2010 Copyright © 2010 the authorsBrain-derived neurotrophic factor (BDNF) signaling is critical for neuronal development and transmission. Recruitment of TrkB receptors to lipid rafts has been hown to be necessary for the activation of specific signaling ...
Assaife-Lopes, Natália +5 more
core +1 more source
Neuropsychiatric Disease and Treatment, 2021 Galen Chan,1 Tea Rosic,2,3 Stanislav Pasyk,2 Mahshid Dehghan,4 Zainab Samaan2,3 1Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada; 2Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton,
Chan G +4 more
doaj
Pharmaceutical Biology, 2020 Context White tea [Camellia sinensis (L) O.Ktze. (Theaceae)] is popular in Asia, but its benefits on olfactory injury are unknown. Objective The present study explores the effects of white tea on the olfactory injury caused by chronic unpredictable mild ...
Wenhao Hu +7 more
doaj +1 more source
BDNF: A Key Factor with Multipotent Impact on Brain Signaling and Synaptic Plasticity
Cellular and molecular neurobiology, 2017 Brain-derived neurotrophic factor (BDNF) is one of the most widely distributed and extensively studied neurotrophins in the mammalian brain. Among its prominent functions, one can mention control of neuronal and glial development, neuroprotection, and ...
P. Kowiański +5 more
semanticscholar +1 more source
Progress in Neurobiology, 2008 At least some neurotrophins may be powerful modulators of synapses, thereby influencing short- and long-term synaptic efficiency. BDNF acts at central synapses in pain pathways both at spinal and supraspinal levels. Neuronal synthesis, subcellular storage/co-storage and release of BDNF at these synapses have been characterized on anatomical and ...
MERIGHI, Adalberto +6 more
openaire +5 more sources
Journal of Neuroscience, 2019 Exercise promotes learning and memory formation. These effects depend on increases in hippocampal BDNF, a growth factor associated with cognitive improvement and the alleviation of depression symptoms.
Lauretta El Hayek +15 more
semanticscholar +1 more source