Results 31 to 40 of about 197,182 (311)

The effect of morphine upon DNA methylation in ten regions of the rat brain

open access: yesEpigenetics, 2017
Morphine is one of the most effective analgesics in medicine. However, its use is associated with the development of tolerance and dependence. Recent studies demonstrating epigenetic changes in the brain after exposure to opiates have provided insight ...
Timothy M. Barrow   +7 more
doaj   +1 more source

The gut-brain axis, BDNF, NMDA and CNS disorders [PDF]

open access: yes, 2016
Gastro-intestinal (GI) microbiota and the ‘gut-brain axis’ are proving to be increasingly relevant to early brain development and the emergence of psychiatric disorders.
Maqsood, Raeesah, Stone, Trevor W.
core   +1 more source

Gene expression and DNA methylation changes in the hypothalamus and hippocampus of adult rats developmentally exposed to bisphenol A or ethinyl estradiol: a CLARITY-BPA consortium study

open access: yesEpigenetics, 2018
Bisphenol A (BPA), an endocrine disrupting chemical (EDC), is a ubiquitous pollutant. As part of the Consortium Linking Academic and Regulatory Insights on BPA Toxicity (CLARITY-BPA), we sought to determine whether exposure of Sprague-Dawley rats to 2 ...
Ana Cheong   +9 more
doaj   +1 more source

Changes in serum brain derived neurotrophic factor following high intensity interval training among obese undergraduates

open access: yesThe Proceedings of the Nigerian Academy of Science, 2021
The study examined changes in Serum Brain Derived Neurotrophic Factor (BDNF) following High Intensity Interval Training (HIIT) programme among obese undergraduates. The pretest-posttest randomized experimental design was employed for the study.
Karl E. Eimuhi   +2 more
doaj   +1 more source

Enriched environment reduces glioma growth through immune and non-immune mechanisms in mice [PDF]

open access: yes, 2015
Mice exposed to standard (SE) or enriched environment (EE) were transplanted with murine or human glioma cells and differences in tumour development were evaluated.
BENIGNI, GIORGIA   +13 more
core   +1 more source

The BDNF rs6265 variant may interact with overweight and obesity to influence obesity-related physical, metabolic and behavioural traits in Pakistani individuals

open access: yesAnnals of Human Biology, 2018
Background: The association of the variant rs6265 (G>A) in the brain-derived neurotrophic factor (BDNF) gene with obesity and other obesity-related parameters is not known for the Pakistani population.
Sobia Rana, Saad Mirza, Soma Rahmani
doaj   +1 more source

The Effect of Pilates Exercises on BDNF Serum Level, Balance and Quality of Life of Menopausal and Non-Menopausal Women [PDF]

open access: yesرشد و یادگیری حرکتی ورزشی
Introduction: Menopause is the beginning of a new era in a woman's life. This period, like all other stages of life, has positive and negative aspects.
sepide jalali   +2 more
doaj   +1 more source

Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence [PDF]

open access: yes, 2011
Depression is a neuropsychiatric disorder affecting a huge percentage of the active population especially in developed countries. Research has devoted much of its attention to this problematic and many drugs have been developed and are currently ...
Berrocoso Domínguez, Esther María   +4 more
core   +4 more sources

Single prazosin infusion in prelimbic cortex Fosters extinction of amphetamine-induced conditioned place preference [PDF]

open access: yes, 2017
Exposure to drug-associated cues to induce extinction is a useful strategy to contrast cue-induced drug seeking. Norepinephrine (NE) transmission in medial prefrontal cortex has a role in the acquisition and extinction of conditioned place preference ...
Alessandro Rava   +8 more
core   +4 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

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